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Pin to quick picksSynairgen Share News (SNG)

Share Price Information for Synairgen (SNG)

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Share Price: 6.20
Bid: 5.52
Ask: 7.00
Change: 0.00 (0.00%)
Spread: 1.48 (26.812%)
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Synairgen shares drop as AstraZeneca stops asthma drug study

Wed, 12th Oct 2016 09:52

(ShareCast News) - Synairgen's, the respiratory drug discovery and development company, hit the skids after its partner Astrazeneca announced that it has dropped its clinical trial for asthma drug AZD9412.AZD9412, which is a form of inhaled interferon beta, was investigated in an INEXAS trial in patients with asthma upon onset of common cold symptoms. Previous studies showed that infection with the common cold can lead to severe exacerbations in asthma patients and dosing with interferon can boost antiviral defences, with the potential for a reduction in severe exacerbations.The Phase IIa trial however found a very low number of reported severe exacerbations making it difficult to determine the effectiveness of the drug.Analyst at N+1 Singer Jamie constable commented on the result saying it was "disappointing".AstraZeneca will review the data and study design before deciding on the best way forward for the programme.Co-founder of Synairgen Professor Stephen Holgate said: "New treatments to prevent severe exacerbations are needed and most exacerbations are caused by the common cold and flu. Unexpectedly, colds did not cause as many asthma exacerbations as were predicted in this clinical trial population. We hope to learn from the results of this trial which population within severe asthma, or other respiratory diseases, will most benefit from AZD9412 and should be included in future trials."Chief Executive Richard Marsden said: "Although the exacerbation rate in the entire population to date has been lower than we expected based on the assumptions behind the trial design, we look forward to reviewing the other clinically important qualitative and quantitative measures of the potential effectiveness of AZD9412, building on the experience of our previous trial outcomes in this section of the asthmatic population."Synairgen's shares dropped 32.35% to 23p at 1624 BST on Wednesday.
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14 Mar 2019 14:47

Synairgen broadens SNG001 trial after committee review

(Sharecast News) - Respiratory drug discovery and development company Synairgen announced on Thursday that its data safety monitoring committee had completed its planned safety review of the second part of the phase 2 clinical trial of its inhaled interferon-beta (IFN-beta) therapeutic candidate, SNG001, in patients with chronic obstructive pulmonary disease (COPD).

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14 Mar 2019 11:37

Synairgen Gets Positive Safety Review Of SNG001 Candidate

LONDON (Alliance News) - Synairgen PLC on Thursday said the Data Safety Monitoring Committee has completed its planned safety review of a clinical trial of therapeutic candidate, SNG001.The

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25 Feb 2019 11:41

Synairgen Swings To Annual Loss As Costs Rise And Revenue Drops

LONDON (Alliance News) - Synairgen PLC on Monday said it swung to an annual loss due to higher research costs and the lack of a non-recurring GBP5 million payment from Pharmaxis received in 2018,

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22 Oct 2018 11:53

Synairgen Begins Dosing For Next Stage Of SNG001 Clinical Trial

LONDON (Alliance News) - Synairgen PLC said Monday it has begun dosing for the next part of its SNG001 chronic obstructive pulmonary disease treatment trial.The respiratory drug discovery a

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22 Oct 2018 09:20

Synairgen begins second part of SNG001 Phase II trial

(Sharecast News) - Respiratory drug discovery and development company Synairgen has started the second part of its Phase II clinical trial for its wholly-owned inhaled interferon-beta (IFN-beta) therapeutic candidate, SNG001, in patients with chronic obstructive pulmonary disease (COPD), it announced on Monday.

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25 Sep 2018 13:48

Synairgen Fundraises To Progress Clinical Tests As Interim Loss Widens (ALLISS)

LONDON (Alliance News) - Synairgen PLC on Tuesday announced fundraising to cover the clinical trials of its wholly-owned antiviral therapy SNG001 after its loss widened in the first half of drug a

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15 Mar 2018 12:57

Synairgen Swings To Profit On Lump Sum Payment As Pipeline Progresses

LONDON (Alliance News) - Respiratory drug development firm Synairgen PLC swung to a full year profit Thursday after a lump sum payment from a collaboration partner offset and

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22 Mar 2016 11:07

Synairgen Swings To Loss But Gets Good LOXL2 Trial Results

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21 Mar 2016 16:06

Earnings, Trading Statements Calendar - Week Ahead

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12 Nov 2015 11:35

DIRECTOR DEALINGS: Synairgen Directors Snap Up 163,000 Shares

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16 Sep 2015 13:03

Synairgen's profit dips, R and D expenditure reduced

(ShareCast News) - Synairgen has posted an after tax loss of £0.91m for the six months to 30 June, down from a profit of £1.90m in the same period last year. The respiratory drug discovery and development company announced its unaudited interim results for the six months ended 30 June 2015. Researc

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16 Sep 2015 09:50

Synairgen Swings To Loss As AstraZeneca Revenue Bump Doesn't Repeat

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5 Aug 2015 10:21

Synairgen shares surge on research collaboration deal

(ShareCast News) - Synairgen surged after announcing that it has entered into a research collaboration deal with Australian pharmaceutical company Pharmaxis. The respiratory drug discovery and development company said they will develop a selective inhibitor to the lysyl oxidase type 2 enzyme to trea

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5 Aug 2015 07:42

Synairgen Signs Research Collaboration Deal With Australia's Pharmaxis

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