Shire leapt into the top spot, rebounding after a heavy sell-off the day before on the back of generic competition issues surrounding its ADHD drug, Adderall XR. The firm was given a lift by Panmure Gordon, Berenberg and Societe Generale, who all upgraded their ratings on the stock. Speciality chemicals group Croda International was another high riser after JP Morgan Cazenove upgraded the stock to 'overweight', lifting its target price from 2,220p to 2,600p. Meanwhile, banks were heavily out of favour this morning. RBS fell on the back of technical issues at Natwest over the last few days, while lenders Barclays and Lloyds were also down, tracking their European counterparts lower. International outsourcing firm Serco also fell after saying it expects revenues in the first half to take a hit from tough conditions in America. FTSE 100 - RisersShire Plc (SHP) 1,793.00p +2.87%British Sky Broadcasting Group (BSY) 673.50p +2.67%Croda International (CRDA) 2,179.00p +2.54%Kazakhmys (KAZ) 691.00p +2.52%Anglo American (AAL) 2,046.50p +1.84%Tate & Lyle (TATE) 645.50p +1.65%Admiral Group (ADM) 1,167.00p +1.57%Eurasian Natural Resources Corp. (ENRC) 405.70p +1.43%Rio Tinto (RIO) 2,913.50p +1.43%CRH (CRH) 1,093.00p +1.39%FTSE 100 - FallersRoyal Bank of Scotland Group (RBS) 228.00p -3.72%Serco Group (SRP) 526.00p -2.59%Smiths Group (SMIN) 983.00p -1.90%Old Mutual (OML) 151.10p -1.69%IMI (IMI) 808.00p -1.58%Glencore International (GLEN) 303.55p -1.49%ARM Holdings (ARM) 492.80p -1.38%Lloyds Banking Group (LLOY) 30.01p -1.32%Amec (AMEC) 937.50p -0.95%Experian (EXPN) 899.00p -0.83%NR