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Share Price Information for Angle (AGL)

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Share Price: 19.00
Bid: 18.50
Ask: 19.50
Change: 0.25 (1.33%)
Spread: 1.00 (5.405%)
Open: 18.75
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Angle Shares Jump As Parsortix System Used In New Cancer Treatment

Thu, 10th Jan 2019 17:05

LONDON (Alliance News) - Angle PLC shares spiked late Thursday afternoon after the company said its Partsortix system will be used in "ground-breaking" new cancer research.

Shares in Angle closed up 77% Thursday at 73.50 pence each.

The research, carried out at the University of Basel in Switzerland, could lead to a new way of treating cancer through the suppression of cancer metastasis.

Angle said the research carried out, using Parsortix, isolated circulating tumor cell clusters, allowing US Food & Drug Administration approved drugs to "dissociate highly metastatic circulating tumor cell clusters resulting in a near total elimination of metastasis in animal models".

Circulating tumor cell clusters is a group of cancer and other cells tethered together as a single mass.

"The ground-breaking circulating tumor cell cluster work undertaken over the last three years by the University of Basel, one of Angle's leading customers, highlights completely new clinical uses for the Parsortix system with the potential to play a central role in dramatically improving patient outcomes," said Founder & Chief Executive Officer Andrew Newland.

"This is a key potential application for Parsortix liquid biopsy once we receive FDA clearance. Our ultimate aim is for the Parsortix system to be routinely used for all cancer patients in the future."

The University of Basel is planning to commence a clinical trial in breast cancer in 2019 using the Parsortix system as a companion diagnostic to identify which patients have circulating tumor cell clusters and may respond to the identified drugs.

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Angle launches tumour cell assay to "unlock" customised cancer care

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31 Aug 2023 15:52

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5 Jun 2023 12:26

IN BRIEF: Angle hires Swansiger as new COO and Miller as new CSO

Angle PLC - Guildford, England-based liquid biopsy company - Hires Brett Swansiger as chief commercial officer and Karen Miller as chief scientific officer. Says Swansiger has over 20 years of experience within the molecular diagnostic and pharmaceutical industries. Most recently, he was COO at DxTerity Diagnostics, a biotechnology company based in the US. Says Miller brings a strong network of relationships within the pharmaceutical and companion diagnostic industries, having over 30 years of experience. She was most recently the CSO at Ixaka, a cell & gene therapy company. Start dates for both roles are undisclosed.

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25 May 2023 14:34

IN BRIEF: Angle customer to use biopsy products in clinical trial

Angle PLC - Guildford, England-based liquid biopsy company - Announces new contract with clinical-stage biotechnology company Artios Pharma for use of two DNA damage response assays in a Phase 1 clinical trial. Artios was Angle's first bespoke assay development customer, selecting it to develop immunofluorescence assays to detect biomarkers on tumour cells. The Phase 1 trial will begin "shortly" with completion expected around the end of 2024. Angle says the assays could later be used in larger and later-stage clinical trials.

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22 May 2023 13:53

IN BRIEF: Angle promotes Jan Groen to chair, replacing Garth Selvey

Angle PLC - Guildford, England-based liquid biopsy company - Chair Garth Selvey plans to retire from the board after interim results are released in September. Selvey has been chair since 2007. he will hand over the position of chair with immediate effect to Jan Groen, who is currently an independent non-executive director. Groen is also currently the chief executive officer and chair of Intravacc BV.

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Angle losses widen in 'breakthrough year'

(Sharecast News) - Liquid biopsy specialist Angle described a "breakthrough year" in its 2022 results on Friday, with both FDA clearance and positive results from the ovarian cancer study being achieved.

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21 Apr 2023 10:43

Angle loss widens in 2022 despite being "breakthrough" year

(Alliance News) - Angle PLC on Friday said it had a "breakthrough" year, despite reporting an annual widened loss.

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19 Apr 2023 17:37

TRADING UPDATES: Angle partners with BioView; First Class hails nickel

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Tougher market conditions impacting Angle clients

(Sharecast News) - Liquid biopsy specialist Angle said in an update on Thursday that actions taken to control its cost base, and the closure of its Canadian operations, left it on track to deliver expected cost savings of £2.6m in 2023 and £4m per annum after that.

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Angle expects 2023 growth to fall short of market expectations

(Alliance News) - Angle PLC on Thursday reported that it expects "growth" in 2023, albeit significantly lower than market estimates, as it anticipates its operating loss to widen.

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