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Pin to quick picksAngle Share News (AGL)

Share Price Information for Angle (AGL)

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Angle Reports Positive Study Results For Parsortix System

Wed, 04th Sep 2019 14:09

(Alliance News) - Angle PLC on Wednesday noted positive results from a study of its Parsortix system in small cell lung cancer.

Parsortix is Angle's liquid biopsy technology, meaning it harvests circulating tumour cells from the blood rather than from the tumour directly.

The study, which was conducted by the Medical University of Vienna, looked at neuroendocrine markers on circulating tumour cells harvested using Parsortix and found that they correlated "with patients' poor overall survival".

Small cell lung cancer is an aggressive cancer, with the majority of patients presenting with a metastatic disease when they are first diagnosed - meaning the cancer has already spread to another part of the body.

Using Parsortix could allow faster diagnosis and allow for repeated biopsies during treatment. It is not usually possible to conduct multiple biopsies on lung cancer patients given the "invasive injury to the patient" and high costs.

Analysis of the harvested cells can also be used to choose drugs and determine the potential effectiveness of new targeted treatments.

Angle Chief Executive Andrew Newland said: "Lung cancer is a major opportunity for Angle to pursue once we have concluded our current [US Food & Drug Administration] and verification studies in breast cancer and ovarian cancer. We are encouraged by the work of Vienna, and others, in this area. There is a clear benefit to lung cancer patients in faster diagnosis, longitudinal monitoring and reducing invasive procedures as well as a strong health economic argument to reduce healthcare costs."

Shares in Angle were up 0.25 at 68.33 pence in London on Wednesday afternoon.

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(Correcting company name in headline)

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3 May 2024 11:50

Angle shares up on assay development deal with AstraZenaca

(Alliance News) - Shares in Angle PLC jumped on Friday, after the company said it has been chosen to develop a prostate cancer assay using its Parsortix technology, opening the door for future clinical study-supporting contracts.

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Angle strikes supplier deal with AstraZeneca

(Sharecast News) - Liquid biopsy technology firm Angle has struck a supplier deal with pharmaceutical giant AstraZeneca to develop an androgen receptor detection assay to enhance prostate cancer studies.

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LONDON BRIEFING: InterContinental Hotels makes first-quarter progress

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24 Apr 2024 17:06

CORRECT: No record close for FTSE 100; mixed trade in US

(Correcting day of the week in the opening sentence.)

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24 Apr 2024 17:00

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(Alliance News) - Stock prices in London closed lower on Thursday, with the FTSE 100's recent rally taking a pause for breath, but not after hitting another record high.

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24 Apr 2024 10:32

Angle shares jump on supplier agreement with with AstraZeneca

(Alliance News) - Angle PLC shares rose on Wednesday, after it signed a contract with AstraZeneca PLC.

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22 Apr 2024 16:52

IN BRIEF: Angle granted patents in US and Europe for Cellkeep slide

Angle PLC - Surrey-based medical diagnostics provider - Says it has been granted a European and US patent for its CellKeep slide. "We are delighted to have secured intellectual property rights for our proprietary CellKeep slide in two major jurisdictions....This is a significant technology advancement for the [circulating tumor cell] liquid biopsy field and another step towards enabling biomarker-guided precision medicine for people with cancer," says Chief Executive Officer Andrew Newland. The CellKeep slide was developed by Angle to reduce cell loss during the transfer of CTCs to the microscope slide and to protect the morphology of the harvested cells.

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22 Apr 2024 06:59

Angle granted European patent for CellKeep, US patent imminent

(Sharecast News) - Liquid biopsy specialist Angle announced on Monday that it has received a European patent for its 'CellKeep' slide, as it anticipated the imminent grant of an equivalent US patent application.

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22 Jan 2024 18:03

IN BRIEF: Angle highlights supportive data for DNA analysis tool

Angle PLC - Surrey-based medical diagnostics provider - Announces publication of a peer-reviewed paper in a special issue of the journal - "Current Issues in Molecular Biology" Special Issue: Advanced Solutions for Cancer Therapy. Article brings together supporting evidence for the additional and complementary information that can be obtained from circulating tumour cells, demonstrating the value of a dual analyte approach for both CTCs and ctDNA (fragments of DNA released mainly by dying cells). Angle recently announced breakthrough data for real-time parallel next generation sequencing DNA analysis of both ctDNA and CTCs from a single tube of patient blood, using a pan-cancer panel run on an Illumina NGS system.

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4 Jan 2024 16:54

LONDON MARKET CLOSE: Stocks up ahead of US nonfarm payrolls

(Alliance News) - Stock prices in London closed higher on Thursday, as investors eye the latest US non-farms data.

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4 Jan 2024 12:19

Angle shares soar following "breakthrough" cancer diagnostics results

(Alliance News) - Angle PLC on Thursday said that "breakthrough results" from its latest blood sample cancer trials would allow it to expand its product sales and pharma services.

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