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Cheers, was hoping to enjoy it and not kill myself before all the SAR money gone lol!!
PHILBORO - has to be the 5L!
I owned one back in 2014 - takes your breath away!!! I’m a speed freak and got it up to speed and warning lights started flashing saying the tyre pressure was too low for that speed!
Epic car, but steering is way too light on the motorway, it’s as if the power steering doesn’t go off so you’re almost fighting with it on bends!
Sometimes you do the work. Sometimes you just get lucky. I give it a week to sink in. But we are ****ting in the lucky pot i think.
Wow that was unexpected on Filgotinib, toxicity again, 200mg too much - 1st class inhibitors legacy problems not suitable for this new world. Nimbus and Jeb should also be worried by this. Nov 5th be interesting, Sareum rockets on order.
SDC1801 target indication shortly and it'll be rapid recruitment if RA or Psoriasis, quick PI with 30 people, but this should be licensed before CTA, can't see how it won't be.
Thanks Thoth,
Would certainly be spiffing if so...
Same indications. Psoriasis arthrititis. Theirs is jak1. Ours is tyk2 and jak1. Ours probably has less tox. And they now have a pipeline hole that we can fill
Top of the evening everyone!
It's a combination of it being a long day and me not being the sharpest tool in the box, but how is the Gilead news relatable to SAR?
I am correct understanding that it's assumed that now that this trial has failed, Gilead will be approaching SAR? If so, is this a speculation/educated speculation/knowledge?
Sorry if it's a daft question,
Best regards,
LR
Ok Dave, was thinking of 5l supercharged but might rethink
I made an error. The gilead galapagos deal was only 725m upfront. 1.3bn further milestones. And a 20% royalty.
https://www.gilead.com/news-and-press/press-room/press-releases/2015/12/galapagos-and-gilead-announce-global-partnership-to-develop-filgotinib-for-the-treatment-of-rheumatoid-arthritis-and-other-inflammatory-diseases
3.0s, you don't need 5.0 the performance isn't that much better.
Will upgrade to a new one if / when we hit 10p but after ten years I'm excited but not holding my breath
Nice one, which one you got mate
A minority of at least two, I bought a five year old f type earlier this year, it's a real head turner and the "asbo" button produces a great sound, for me it was this or Aston I think I chose right and a weekend in the Cairngorms made me sure.
Maybe I’m in minority but I prefer the Ftype coupe
I test drove an Ftype 5 ltr gorgeous sound and so quick. But the Aston is very tempting.
Dont get too carried away I was in GKP from 14p & it went to £4 with rumours of double digit takeover. There was a get together party & then the slide. Hopefully, differing outcome here.
DBX deposit c £16k - full spec c £200k - I’ve checked!!
Was looking at a second hand Ftype for new year but think I’ll just use the pocket change from SAR for a new one now in April, or maybe Aston if it explodes before then, I’ll drive down to the party in it :)
Filgotinib Sales Forecast - $4.3bn (£3.3bn) by 2026 and now they have toxicity issues......
Filgotinib Sales Forecast - $4.3bn (£3.3bn) by 2026 and now they have toxicity issues......
Its a confident ten bag once the market digests. Gla. Ill be ****ed for a week xxx