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well looks like we are starting to sink, day by day. I think Shire or Xbio need to release more information or positive news to try keep us afloat! or, does Shire really care?
No idea what good it'll do but I've raised a complaint against II with the FOS. Having had numerous emails with Rico Portaro at Empire Stock Transfer Inc. and Jim Parslow at XBIO it's my final throw of the dice to see if I can get the process moving.
Nice one, Ace. I can almost guarantee you'll get the same brush-off email I got from the PR/IR woman, but at least we've let them know there are people watching. Radio silence from Maguire at this point.
Hi Care to share the strategy moving forward? All long-standing shareholders are no doubt disappointed as the shire end points were not met despite being reassured by the mgmt that the science was in tact. Years of disappointment on all fronts is intolerable now not to mention the loss of investment opportunities. Kindly update and post the company position. Message sent to Jeanine hope the rest of us will follow up on snooties recommendation to elicit a response. Cheers
Hi Care to share the strategy moving forward? All long-standing shareholders are no doubt disappointed as the shire end points were not met despite being reassured by the mgmt that the science was in tact. Years of disappointment on all fronts is intolerable now not to mention the loss of investment opportunities. Kindly update and post the company position. Message sent to Jeanine hope the rest of us will follow up on snooties recommendation to elicit a resoonse. Cheers
At the moment we are defying gravity. Whether it's because low free float allows the SP to be propped up cheaply, or whether it's because someone knows something we don't, is not clear. I suggest we all pester the Company and their PR/IR for some answers - that is what I have been doing. I doubt we will receive individual replies, but perhaps it will make the Company aware how appalling it is that two weeks after a wholly optimistic conference call, we are now left without any guidance as to the future, after the failure of SHP656 to achieve a key metric.
Sigh! Many of us long term sufferers hung in by accepting the unnecessary delays caused by mgmt to reach Nasdaq. Accepted dilution all because of Scott's quote "the science is working". Now, that too has raised a question mark. No follow up communication to shareholders post shire phase 1/2 study announcement. Share price behaviour uncannily resembles an insiders trading pattern, defying all logical conclusions deliverable from recent announcement and short term pipeline expectations of xbio. Anyone care to share a thought on recent trading pattern of xbio or insights.
Agree, gentlemen, this has been a shabby deal at every level right from the beginning: marooned on some rubbish market for three years through some bright spark's idea to fast track to NASDAQ turned into a slow track to nowhere; then when we finally achieve a NASDAQ listing, the IPO's at a fraction of what we paid. Then EPO doesn't come up to scratch in the Oz trials; now the same has happened with SHP656. Meanwhile directors pay themselves lavish salaries and award each other stock options. I am at about ⅓ the price I bought at more than five years ago.
I have sent an email to Rico @ Empire Stock Transfer detailing the issues I am having with II and waiting to see if he can suggest anything. Having spoken to II again they have said that I cannot get a paper copy of my share certificate as it is 'being held in residuals'. I know that this share may never materialise any profit however it's the principle of being told that I cannot do anything and being given no timescale as to whether anything will ever be done.
Had mine through HL when on AIM. they do not support OTCBB so transferred into certificate form for me (it had a purple border IIRC). I opened a Stocktrade account, and bought some more on the last few days of AIM. I then had a holidng with them plus a certificate I transferred in. there was a looooooooong delay but finally my shares all appeared in the account after many followups. I believe there was a delay with Empire stock transfer as well as their US Custodian. It also helped that another holder is a friend and I knew his shares had gone through earlier so I could turn the screw with stocktrade, and they could turn the screw with their US counterparty. Stocktrade was bought out by Alliance trust and the move from OTCBB to NASDAQ as well as the consolidation of shares etc was seamless. One caveat - I have not tried to trade the shares on NASDAQ but I have contacted them and they say they would be OK to trade and were surprised I was asking. I would say that if you are still holding OTCBB certificate that we all got when it came off AIM, it would be a bit complex to convert into NASDAQ now which might be a cause of your troubles
Clem - as I said before, I use iWeb share dealing, part of Halifax. IG too.
I'm perplexed, as we all are, by the terse announcement Monday. I have no idea what's going on but am glad we haven't dropped further - yet.
No problem trading with Halifax...
No problem trading with Halifax...
Can you clarify when you bought your shares and with what broker and also that you can now trade them on Nasdaq if you wish so I can start to put more pressure on II . They are regulated by FCA so I will be getting in touch with them to start. Cheers Clem
no more opinions on yesterday's (or even this morning's) weirdness? what say you m'lord?
Hi Road Im in the same boat as you Im going to contact the financial services Ombudsman to see what the position is. I will keep you updated. Cheers Clem
maybe we will end Up for the day?! who knows with this share
26% down - oh dear. to the person looking for their certificate - perhaps the gold edged paper will be worth more
big shock to Scott no doubt- and me
LEXINGTON, Mass.--(BUSINESS WIRE)-- Xenetic Biosciences, Inc. (NASDAQ:XBIO) (“Xenetic” or the “Company”), a clinical-stage biopharmaceutical company focused on the discovery, research and development of next-generation biologic drugs and novel orphan oncology therapeutics, announced today that it has received an update on the Phase 1/2 clinical study conducted by its partner Shire, evaluating SHP656 (“PSA-recombinant Factor VIII”, “PSA-rFVIII”), which is being developed as a long-acting therapeutic for the treatment of hemophilia A utilizing Xenetic's PolyXen™ platform technology to conjugate polysialic acid to therapeutic blood-clotting factors. The Phase 1/2 study demonstrated SHP656’s efficacy and pharmacokinetic data commensurate with the profile of an extended half-life rFVIII product. Additionally, there were no drug-related adverse events, serious adverse events, or rFVIII inhibitors reported. However, in this study, a pre-defined once-weekly dosing criterion was not met. "Despite not achieving the principal objective of once-weekly dosing in this Phase 1/2 study, our PolyXen technology clearly works as a platform to successfully extend the circulating half-life of rFVIII with no drug-related serious adverse events,” stated M. Scott Maguire, Xenetic’s Chief Executive Officer. “Including our own studies with a polysialylated erythropoietin (“PSA-EPO”, “ErepoXen®”) candidate, this is the second instance in which PolyXen has been demonstrated, in a human clinical trial setting, to confer extended half-life to a biotherapeutic, while maintaining pharmacological activity and a favorable safety and tolerability profile. Moving forward, we believe data from Shire’s SHP656 program continues to support the broad utility of our proprietary PolyXen technology platform, and we remain focused on building a growing pipeline of partnerships utilizing this proven platform. We truly value our continuing relationship with Shire and look forward to exploring other potential applications of PolyXen within the Shire portfolio,” added Mr. Maguire. “While Shire is disappointed by this outcome, the company is encouraged by the knowledge gained through this research and remains committed to transforming the treatment landscape for patients with bleeding disorders. Given the potential application of polysialic acid technology, the companies will explore future collaborations,” stated Philip Vickers, Ph.D., Global Head of Research & Development at Shire.
Are we screwed? will investors be spooked and we become a takeover target? or merely a temporary blip - hopefully
Don't fret, the shares won't be worth the paper they were printed on after market opens
Just to add, this would all be very well if I had a copy of my share certificate however I don't and II cannot provide me with one!!
So I had an email from XBio's CFO, James Parslow.... In order to trade on Nasdaq, you will need to dematerialize your shares. To do so, you will need to complete a DRS Account Application attached with this e-mail, have it notarized and send it to our transfer agent. You will need to include your original share certificate, a cover letter, a copy of your government issued ID and $55 in fees. The transfer agent contact information is as follows: Rico Portaro Empire Stock Transfer, Inc. 1859 Whitney Mesa Dr. Henderson, NV 89014 rico@empirestock.com P: 702-818-5898 F: 702-974-1444 www.empirestock.com The form must be notarized. There are companies who provide online notary services. www.notarycam.com I have absolutely no idea what this means although the implication is that II will never allow me to trade through them.