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Algy7... that is absolutely accurate, and very well explained.
Astra also sadly pulled out BEFORE they knew that considerable efficacy was shown in the patients with a viral infection. But testing has moved on a whole lot since then... so this would no longer be an issue in future trials.
But Dumbpunter knows all this, we've covered it many times over the last few years.... he is deliberately misleading on this and other boards.
Dumbpunter......
Asthma trial was run by Astra, not Synairgen........and their choice of patients were not careful enough. It was found later that many of the patients had a bacterial infection ( which needs antibiotics) not a viral infection ( which would have responded to antivirals, such as SNG001). When the results were revamped by Synairgen later to include only the viral infections, they showed considerable efficacy.
COPD......this trial was stopped when the covid pandemic was announced. This is normal and very ethical, because many of those on the trial were highly vulnerable to Covid and were not to be encouraged to attend appointments in hospital or continue their stays in hospital and unfortunately many did still catch covid and die/became very sick. This would clearly have distorted the future results. Additionally, when on a trial, the patients are denied further , possibly life saving , drugs.
I think we are going to the moon.
As I posted back in June, and August and November....
Dumbpunter you are either stupid or a liar.....
Gunto, What do you mean 'pandering to the likes of Dumbpunter' what you say makes no sense whatsoever.
I have provided a correct link to back up BeContrarians comment which explains that the COPD/asthma trials DID NOT fail.
Takes a big man to just say I got it wrong and apologise, so I politely invite you to do so. If you don't, then for both our sakes, please just filter me as you said you had before !!!
You may enjoy these mud slinging games. I just can't be bothered with the nonsense.
I’ve reported Dumbs post, you can’t post blatant falsehoods. It’s not cricket old boy.
Harvesting multiple accounts is a really sad state to be in.
I thought you had left for the 17th time a few weeks ago, but here we are again, pandering to the likes of Dumbpunter.
Sad man.
Gunto, why have you included my name in that list???
It's like you take delight in unfounded personal vendetta's.
Really sad state to be in.
All the best lies need somebody to believe them and here is the return of Robert (Winit / Org / Seb / Dan) to meet that requirement.
Don't despair BC, my child insists there's a man in the moon. And you know, there's just dust and some weird lunar tumbleweed on the moon, what can I say? I let it ride, he'll learn eventually...
BeContrarian, the link you posted didn't work for me. I think try:
https://www.synairgen.com/programmes/ifn-%CE%B2-sng001-in-copd/
Dumpunter why did you say it failed on efficacy ??
Gingerish....note above and good luck.
No it wasn’t. The trial was paused due the pandemic. Hell it even says so on the website. Jeez…
https://www.synairgen.com/programmes/ifn-ß-sng001-in-copd/
While most of the interest in SNG is around Covid mine is around COPD and Asthma;
I am not just interested, I am really excited.
I am 65 , very fit, and co-exist, usually peacefully, with chronic mild asthma ( daily inhaled steroid , well managed, antibiotics 2 or 3 times a year for fully fledged lower chest infections including pneumonia ). For those that do not have asthma it might be difficult to grasp the trepidation that comes with the coughing and slow burn in the upper respiratory tract that inexorably drops down into the lower chest and the subsequent long wheeze! I have long had an image of what the future might well hold for me. That is , departing the mortal coil gasping for air following a respiratory infection that I am no longer to fight off.
My observations have been attenuated by the experience of a 92 yr old acquaintance , fit as a fiddle and bright as a button, who recently developed a chest infection and two weeks later succumbed in hospital gasping like a fish stranded on the side of a river bank . The older one gets the more frequent and worse these infections become.
So I was uplifted to see the matter being discussed, when I looked at a link posted on this site on 16 (? ) November.
From: American Journal of Respiratory Medicine on 15 Nov. “ Balancing benefits and risks : Do Inhaled Corticosteroids modify the lung biome”.
https://bit.ly/3chf2gy
The gist being that while steroid inhalers are fantastic for healthy lung maintenance in asthmatics, they actually suppress interferon production at the point of greatest need once a lower respiratory tract infection gets started. Yet… in my own experience… I am currently advised by my GP to increase my twice daily inhaled doses to 3 or even 4 times when being treated for infection. Is it possible that THIS is one reason why my recoveries seem to be so prolonged?
So maybe, in the future, treatments for Lower respiratory tract infections will routinely include SNG supplied interferon , as opposed to doubling up on asthma inhalers?