Issue of Equity

ValiRx Plc

("ValiRx" or the "Company")

Issue of Equity

ValiRx announces that, on 13 August 2010, the Company issued 7,407,333 new ordinary shares of 0.1p each ("Ordinary Shares") to Cancer Research Technology Limited ("CRT") at an issue price of 0.45p per share, being the mid-market price of the Ordinary Shares on 13 August 2010. The share issue was in respect of the payment of milestones and other payments due to CRT according to the terms and conditions of the option agreement entered into in 2008 with CRT and the subsequent licensing agreement with CRT signed on 11 August 2010.

Application has been made for the new Ordinary Shares to be admitted to trading on AIM and dealings are expected to commence on 19 August 2010. Following the issue of the new Ordinary Shares, the total number of Ordinary Shares now in issue is 343,923,790.

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