Issue of Equity

THIS ANNOUNCEMENT IS NOT FOR RELEASE, PUBLICATION OR DISTRIBUTION, DIRECTLY OR INDIRECTLY, IN WHOLE OR IN PART, IN, INTO OR FROM JAPAN, CANADA OR AUSTRALIA OR ANY OTHER JURISDICTION WHERE TO DO SO WOULD CONSTITUTE A BREACH OF THE RELEVANT SECURITIES LAWS OF SUCH JURISDICTION.

TYRATECH, INC.

("TyraTech" or the "Company")

Issue of Equity

TyraTech, Inc. (AIM: TYR), a natural life sciences company, announces that it has issued 600,000 new common shares of $0.001 each in the capital of the Company (the "New Common Shares") at 5 pence per share to First Columbus LLP ("First Columbus") in consideration of services provided under the Company's corporate broking agreement with First Columbus.

Application has been made to the London Stock Exchange for the New Common Shares to be admitted to trading on AIM ("Admission"). It is expected that Admission and the commencement of dealings will take place on 12 March 2012.

Following Admission, the Company will have 105,057,678 common shares of $0.001 each in issue. The number of restricted common shares trading under TIDM 'TYR' following Admission will be 93,265,356 and the number of unrestricted common shares trading under TIDM 'TYRU' following Admission will be 11,792,322.

For further information please contact:

TyraTech Inc.

Alan Reade, Executive Chairman

Tel: +1 919 415 4310

Peter Jerome, Chief Financial Officer

Tel: +1 919 415 4280

N+1 Brewin, Nominated Adviser and Joint Broker

Aubrey Powell/ Robert Beenstock

Tel: +44 20 3201 3170

First Columbus LLP, Joint Broker

Chris Crawford

Tel: 020 3002 2070