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Director/PDMR Shareholding

27 Nov 2006 10:56

SR Pharma plc

Grant of Options

London 27 November 2006 - SR Pharma plc (the Company) announces the grant on Friday 24 November of options over SR Pharma Ordinary Shares of 1p each under the Company's unapproved share option scheme to directors and staff as follows:

Number of Exercise Earliest Latest exercise date options price exercise date Iain Ross 400,000 43p Immediate 24 November 2016 Melvyn Davies 200,000 43p Immediate 24 November 2016

In addition, 600,000 options have been granted on the same terms to management of SR Pharma's subsidiary, Atugen AG.

The exercise price is the market price at close of business on Friday 24November. - Ends - SR Pharma (www.srpharma.com)

SR Pharma plc is a European biopharmaceutical company, listed on AIM. The Company has two operating subsidiaries Atugen AG (www.atugen.com) based in Berlin, Germany and Stanford Rook Ltd based in London, UK.

Atugen is a leader in RNAi therapeutics. This Company has developed novel, chemically modified proprietary siRNA molecules ("AtuRNAi") and a proprietary delivery system ("AtuPLEX") both of which have advantages over conventional siRNA molecules and their delivery systems. Currently Atugen and its collaboration partners have lead molecules in pre-clinical development for a variety of therapeutic indications. Clinical development of AtuRNAi therapeutic molecules for systemic applications in Atugen's oncology programs are targeted to start in 2007. Other clinical AtuRNAi therapeutic programs of Atugen's collaborators are scheduled to commence in 2H 2006.

Stanford Rook Ltd owns a proprietary Mycobacterium vaccae-based technology and related products, and a number of other proprietary immunotherapeutic compounds and related intellectual property. Currently the Company is in discussions with third parties regarding the co-development and out-licensing of M. vaccae and related products.

Forward-Looking Statements

This press release includes forward-looking statements that are subject to risks, uncertainties and other factors. These risks and uncertainties could cause actual results to differ materially from those referred to in the forward-looking statements. All forward--looking statements are based on information currently available to SR Pharma and SR Pharma assumes no obligation to update any such forward-looking statements.

Enquiries:

For further information, please contact the following:

SR Pharma plc Atugen AG +44(0)20 7307 1620 +49(0)30 9489 2800 Iain Ross, Chairman Thomas Christĩly, Chief Executive Officer

Melvyn Davies, Finance Director Dr. Klaus Giese, Chief Scientific

Officer Northbank Communication +44(0)20 7886 8150 Sue Charles, Justine Lamond

srpharma@northbankcommunications.com

SR PHARMA PLC
Date   Source Headline
3rd Apr 20079:41 amPRNDirector/PDMR Shareholding
30th Mar 20077:10 amPRNNotice of EGM
30th Mar 20077:00 amPRNPreliminary Final Results
16th Mar 20077:00 amPRNResearch Update
28th Feb 20074:23 pmPRNHolding(s) in Company
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21st Feb 20077:30 amPRNHolding(s) in Company
21st Feb 20077:00 amPRNResearch Update
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5th Feb 20077:00 amPRNResearch Update
30th Jan 20077:00 amPRNResearch Update
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3rd Jan 20077:30 amPRNResearch Update
15th Dec 200611:10 amPRNTotal Voting Rights
11th Dec 20067:02 amRNSNobel Prize Congratulations
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23rd Nov 200610:15 amPRNIssue of Equity
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27th Sep 20063:55 pmPRNHolding(s) in Company
26th Sep 200610:00 amPRNRe Agreement
13th Sep 20068:30 amPRNResearch Update
1st Sep 200612:53 pmPRNHolding(s) in Company
24th Aug 20067:00 amPRNHolding(s) in Company
23rd Jun 20063:15 pmPRNResearch Update
23rd Jun 20067:30 amPRNFinal Results
15th Jun 200612:00 pmPRNResearch Update
6th Jun 20067:00 amPRNResearch Update
3rd May 20065:05 pmPRNIssue of Equity
24th Apr 200611:15 amPRNResearch Update
28th Mar 200612:40 pmPRNLicence agreement signed
20th Dec 200511:36 amPRNIssue of Equity
28th Sep 20056:30 amPRNInterim Results
27th Sep 200510:10 amPRNNotice of Results
21st Sep 20052:30 pmPRNIssue of Equity
1st Aug 200511:01 amPRNAdditional Listing
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28th Jul 20056:30 amPRNResult of Equity Issue
12th Jul 20053:06 pmPRNHolding(s) in Company
11th Jul 200512:12 pmPRNResult of EGM
30th Jun 20059:43 amPRNAGM Statement
24th Jun 20054:41 pmRNSSchedule 1 - SR Pharma PLC
24th Jun 20052:30 pmRNSRestoration - SR Pharma PLC
24th Jun 20051:30 pmPRNPublication of Circular to Shareholders
21st Jun 20057:45 amRNSSuspension - SR Pharma PLC
21st Jun 20056:45 amPRNAcquisition(s)
9th Jun 20054:45 pmPRNNotice of AGM

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