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Form 8.5 (EPT/NON-RI)

19 Dec 2018 14:36

RNS Number : 0146L

Citigroup Derivatives Markets Inc

19 December 2018

FORM 8.5 (EPT/NON-RI)

PUBLIC OPENING POSITION DISCLOSURE/DEALING DISCLOSURE BY AN

EXEMPT PRINCIPAL TRADER WITHOUT RECOGNISED INTERMEDIARY ("RI") STATUS (OR WHERE RI STATUS IS NOT APPLICABLE)

Rule 8.5 of the Takeover Code (the "Code")

1. KEY INFORMATION

(a) Name of exempt principal trader:	Citigroup Derivatives Markets Inc.
(b) Name of offeror/offeree in relation to whose relevant securities this form relates: Use a separate form for each offeror/offeree	Shire Plc
(c) Name of the party to the offer with which exempt principal trader is connected:	Shire Plc
(d) Date position held/dealing undertaken: For an opening position disclosure, state the latest practicable date prior to the disclosure	18 December 2018
(e) In addition to the company in 1(b) above, is the exempt principal trader making disclosures in respect of any other party to the offer? If it is a cash offer or possible cash offer, state "N/A"	NO

2. POSITIONS OF THE EXEMPT PRINCIPAL TRADER

If there are positions or rights to subscribe to disclose in more than one class of relevant securities of the offeror or offeree named in 1(b), copy table 2(a) or (b) (as appropriate) for each additional class of relevant security.

(a) Interests and short positions in the relevant securities of the offeror or offeree to which the disclosure relates following the dealing (if any)

Class of relevant security:	5p Ordinary
	Interests		Short positions
	Number	%	Number	%
(1) Relevant securities owned and/or controlled:	44,127	(0.00%)	59,794	(0.01%)
(2) Cash-settled derivatives:
(3) Stock-settled derivatives (including options) and agreements to purchase/sell:	1,011,600	(0.11%)	1,007,500	(0.10%)
TOTAL:	1,055,727	(0.11%)	1,067,294	(0.11%)

All interests and all short positions should be disclosed.

Details of any open stock-settled derivative positions (including traded options), or agreements to purchase or sell relevant securities, should be given on a Supplemental Form 8 (Open Positions).

(b) Rights to subscribe for new securities (including directors' and other employee options)

Class of relevant security in relation to which subscription right exists:
Details, including nature of the rights concerned and relevant percentages:

3. DEALINGS (IF ANY) BY THE EXEMPT PRINCIPAL TRADER

Where there have been dealings in more than one class of relevant securities of the offeror or offeree named in 1(b), copy table 3(a), (b), (c) or (d) (as appropriate) for each additional class of relevant security dealt in.

The currency of all prices and other monetary amounts should be stated.

(a) Purchases and sales

Class of relevant security

Purchases/ sales

Total number of securities

Highest price per unit paid/received (USD)

Lowest price per unit paid/received (USD)

5p Ordinary

Purchase

2,500

167.1433

166.2389

5p Ordinary

Sale

2,000

165.4169

(b) Cash-settled derivative transactions

Class of relevant security

Product description

e.g. CFD

Nature of dealing

e.g. opening/closing a long/short position, increasing/reducing a long/short position

Number of reference securities

Price per unit

(i) Writing, selling, purchasing or varying

Class of relevant security	Product description e.g. call option	Writing, purchasing, selling, varying etc.	Number of securities to which option relates	Exercise price per unit	Type	Expiry date	Option money paid/ received per unit
5p Ordinary	Call	Purchasing	100	170	American	15/01/2021	10
5p Ordinary	Call	Purchasing	100	170	American	15/01/2021	10
5p Ordinary	Call	Purchasing	100	170	American	15/01/2021	10
5p Ordinary	Call	Writing	100	170	American	15/01/2021	10.1
5p Ordinary	Call	Writing	100	170	American	15/01/2021	10.1
5p Ordinary	Call	Writing	200	170	American	15/01/2021	10.1
5p Ordinary	Call	Writing	1000	170	American	15/01/2021	10.2
5p Ordinary	Put	Writing	100	160	American	18/01/2019	2.48
5p Ordinary	Put	Writing	100	160	American	18/01/2019	2.49
5p Ordinary	Put	Writing	500	160	American	18/01/2019	2.48
5p Ordinary	Put	Purchasing	500	115	American	17/01/2020	0.3
5p Ordinary	Put	Purchasing	100	145	American	18/01/2019	0.83
5p Ordinary	Put	Purchasing	100	145	American	18/01/2019	0.84
5p Ordinary	Put	Purchasing	500	145	American	18/01/2019	0.83
5p Ordinary	Call	Purchasing	100	185	American	18/01/2019	0.6
5p Ordinary	Call	Purchasing	400	185	American	18/01/2019	0.5
5p Ordinary	Call	Purchasing	400	185	American	18/01/2019	0.6
5p Ordinary	Call	Purchasing	700	185	American	18/01/2019	0.6
5p Ordinary	Call	Purchasing	800	185	American	18/01/2019	0.6
5p Ordinary	Call	Purchasing	800	185	American	18/01/2019	0.6
5p Ordinary	Call	Writing	100	170	American	18/01/2019	3.5
5p Ordinary	Call	Writing	100	170	American	18/01/2019	3.5
5p Ordinary	Call	Writing	100	170	American	15/01/2021	10.1
5p Ordinary	Call	Writing	100	170	American	15/01/2021	10.3
5p Ordinary	Call	Writing	100	170	American	15/01/2021	10.6
5p Ordinary	Call	Writing	100	175	American	18/01/2019	2
5p Ordinary	Call	Writing	400	175	American	18/01/2019	1.8
5p Ordinary	Call	Writing	400	175	American	18/01/2019	2.05
5p Ordinary	Call	Writing	700	175	American	18/01/2019	2.25
5p Ordinary	Call	Writing	800	175	American	18/01/2019	2
5p Ordinary	Call	Writing	800	175	American	18/01/2019	2.1
5p Ordinary	Call	Writing	500	170	American	15/01/2021	10.1
5p Ordinary	Call	Writing	500	170	American	15/01/2021	10.1
5p Ordinary	Call	Writing	100	170	American	15/01/2021	10.1
5p Ordinary	Call	Writing	400	170	American	15/01/2021	10.1
5p Ordinary	Call	Writing	100	170	American	15/01/2021	10.1
5p Ordinary	Call	Writing	100	170	American	15/01/2021	10.1
5p Ordinary	Call	Writing	100	170	American	15/01/2021	10.1
5p Ordinary	Call	Writing	100	170	American	15/01/2021	10.1
5p Ordinary	Call	Writing	100	170	American	15/01/2021	10.1
5p Ordinary	Call	Writing	100	170	American	15/01/2021	10.1
5p Ordinary	Call	Writing	100	170	American	15/01/2021	10.1
5p Ordinary	Call	Writing	100	170	American	15/01/2021	10.1
5p Ordinary	Call	Writing	400	170	American	15/01/2021	10.4
5p Ordinary	Call	Writing	100	170	American	15/01/2021	10.5
5p Ordinary	Call	Writing	100	170	American	15/01/2021	10.5
5p Ordinary	Call	Writing	100	170	American	15/01/2021	10.3
5p Ordinary	Call	Writing	100	170	American	15/01/2021	10.6
5p Ordinary	Put	Purchasing	500	120	American	18/04/2019	0.35
5p Ordinary	Put	Writing	200	160	American	18/01/2019	2.45
5p Ordinary	Put	Purchasing	200	145	American	18/01/2019	0.85
5p Ordinary	Put	Writing	200	160	American	18/01/2019	2.35
5p Ordinary	Put	Purchasing	200	145	American	18/01/2019	0.75
5p Ordinary	Call	Writing	600	175	American	21/12/2018	0.2
5p Ordinary	Call	Writing	100	175	American	21/12/2018	0.2
5p Ordinary	Call	Writing	100	175	American	21/12/2018	0.2
5p Ordinary	Call	Writing	100	175	American	21/12/2018	0.2
5p Ordinary	Call	Writing	100	175	American	21/12/2018	0.2
5p Ordinary	Call	Writing	100	175	American	21/12/2018	0.2
5p Ordinary	Call	Writing	100	175	American	21/12/2018	0.2
5p Ordinary	Call	Writing	100	175	American	21/12/2018	0.25
5p Ordinary	Call	Writing	100	175	American	21/12/2018	0.25
5p Ordinary	Call	Writing	100	175	American	21/12/2018	0.25
5p Ordinary	Call	Writing	100	170	American	18/01/2019	3.7
5p Ordinary	Call	Writing	400	170	American	15/01/2021	10.4
5p Ordinary	Call	Writing	400	170	American	15/01/2021	10.4
5p Ordinary	Put	Purchasing	200	165	American	21/12/2018	1.54
5p Ordinary	Put	Purchasing	200	165	American	18/01/2019	4.03
5p Ordinary	Call	Writing	10000	175	American	21/12/2018	0.25
5p Ordinary	Call	Writing	400	170	American	15/01/2021	10.5
5p Ordinary	Call	Writing	500	170	American	15/01/2021	10.1
5p Ordinary	Call	Writing	500	170	American	15/01/2021	10.2
5p Ordinary	Call	Writing	500	170	American	15/01/2021	10.2
5p Ordinary	Call	Writing	700	170	American	15/01/2021	10.5
5p Ordinary	Call	Writing	700	170	American	15/01/2021	10.5
5p Ordinary	Call	Writing	700	170	American	15/01/2021	10.5
5p Ordinary	Call	Writing	900	170	American	18/01/2019	3.1
5p Ordinary	Call	Writing	1000	170	American	15/01/2021	10.1
5p Ordinary	Call	Writing	1000	170	American	15/01/2021	10.1
5p Ordinary	Call	Writing	1000	170	American	15/01/2021	10.2
5p Ordinary	Call	Writing	1000	170	American	15/01/2021	10.2
5p Ordinary	Call	Writing	1000	170	American	15/01/2021	10.2
5p Ordinary	Call	Writing	1400	170	American	18/01/2019	3.1
5p Ordinary	Call	Writing	1500	170	American	18/01/2019	3.4
5p Ordinary	Call	Writing	2500	170	American	15/01/2021	10.5
5p Ordinary	Put	Writing	4000	165	American	21/12/2018	1.58
5p Ordinary	Put	Writing	5000	165	American	21/12/2018	1.7
5p Ordinary	Put	Writing	100	155	American	18/01/2019	1.95
5p Ordinary	Put	Writing	200	155	American	18/01/2019	2
5p Ordinary	Put	Writing	500	155	American	18/01/2019	1.9
5p Ordinary	Put	Writing	500	155	American	18/01/2019	1.9
5p Ordinary	Put	Writing	600	155	American	18/01/2019	2.05
5p Ordinary	Put	Writing	900	155	American	18/01/2019	1.85
5p Ordinary	Put	Writing	900	155	American	18/01/2019	1.9
5p Ordinary	Put	Writing	900	155	American	18/01/2019	1.9
5p Ordinary	Put	Writing	900	155	American	18/01/2019	2
5p Ordinary	Put	Writing	900	155	American	18/01/2019	2.1
5p Ordinary	Put	Writing	1000	155	American	18/01/2019	1.9
5p Ordinary	Put	Writing	1000	155	American	18/01/2019	1.9
5p Ordinary	Put	Writing	1000	155	American	18/01/2019	1.9
5p Ordinary	Put	Writing	1000	155	American	18/01/2019	1.9
5p Ordinary	Put	Writing	1300	155	American	18/01/2019	1.8
5p Ordinary	Put	Writing	100	160	American	18/01/2019	2.48
5p Ordinary	Put	Purchasing	2300	160	American	18/04/2019	5.3
5p Ordinary	Put	Purchasing	100	160	American	21/12/2018	0.55
5p Ordinary	Put	Purchasing	4000	160	American	21/12/2018	0.58
5p Ordinary	Put	Purchasing	5000	160	American	21/12/2018	0.65
5p Ordinary	Put	Purchasing	1100	162.5	American	21/12/2018	1
5p Ordinary	Put	Purchasing	1000	105	American	17/01/2020	0.1
5p Ordinary	Put	Purchasing	100	145	American	18/01/2019	0.83
5p Ordinary	Call	Writing	100	170	American	15/01/2021	10.3
5p Ordinary	Call	Writing	100	170	American	15/01/2021	10.5

(ii) Exercise

Class of relevant security	Product description	Exercising/ exercised against	Number of securities	Exercise price per unit

(d) Other dealings (including subscribing for new securities)

Class of relevant security

Nature of dealing

e.g. subscription, conversion

Details

Price per unit (if applicable)

4. OTHER INFORMATION

(a) Indemnity and other dealing arrangements

Details of any indemnity or option arrangement, or any agreement or understanding, formal or informal, relating to relevant securities which may be an inducement to deal or refrain from dealing entered into by the exempt principal trader making the disclosure and any party to the offer or any person acting in concert with a party to the offer:

Irrevocable commitments and letters of intent should not be included. If there are no such agreements, arrangements or understandings, state "none"

N/A

(b) Agreements, arrangements or understandings relating to options or derivatives

Details of any agreement, arrangement or understanding, formal or informal, between the exempt principal trader making the disclosure and any other person relating to:

(i) the voting rights of any relevant securities under any option; or

(ii) the voting rights or future acquisition or disposal of any relevant securities to which any derivative is referenced:

If there are no such agreements, arrangements or understandings, state "none"

N/A

Is a Supplemental Form 8 (Open Positions) attached?

YES

Date of disclosure:	18 December 2018
Contact name:	Craig Watson
Telephone number:	02890 409 6905

Public disclosures under Rule 8 of the Code must be made to a Regulatory Information Service.

The Panel's Market Surveillance Unit is available for consultation in relation to the Code's disclosure requirements on +44 (0)20 7638 0129.

The Code can be viewed on the Panel's website at www.thetakeoverpanel.org.uk.

SUPPLEMENTAL FORM 8 (OPEN POSITIONS)

DETAILS OF OPEN STOCK-SETTLED DERIVATIVE (INCLUDING OPTION) POSITIONS, AGREEMENTS TO PURCHASE OR SELL ETC.

Note 5(i) on Rule 8 of the Takeover Code (the "Code")

1. KEY INFORMATION

Full name of person making disclosure:	Citigroup Derivatives Markets Inc.
Name of offeror/offeree in relation to whose relevant securities the disclosure relates:	Shire Plc.

2. STOCK-SETTLED DERIVATIVES (INCLUDING OPTIONS)

Class of relevant security	Product description e.g. call option	Written or purchased	Number of securities to which option or derivative relates	Exercise price per unit	Type	Expiry date
5p Ordinary	Call	Purchased	300	175	American	2019-01-04
5p Ordinary	Call	Written	300	180	American	2019-01-04
5p Ordinary	Call	Purchased	400	190	American	2019-01-11
5p Ordinary	Call	Purchased	1000	190	American	2019-01-11
5p Ordinary	Put	Written	1000	130	American	2021-01-15
5p Ordinary	Put	Written	45400	130	American	2021-01-15
5p Ordinary	Put	Written	400	130	American	2021-01-15
5p Ordinary	Put	Written	2200	135	American	2021-01-15
5p Ordinary	Put	Written	800	135	American	2021-01-15
5p Ordinary	Put	Written	500	140	American	2021-01-15
5p Ordinary	Put	Written	100	145	American	2021-01-15
5p Ordinary	Call	Purchased	7500	150	American	2021-01-15
5p Ordinary	Put	Written	2900	150	American	2021-01-15
5p Ordinary	Put	Written	13600	150	American	2021-01-15
5p Ordinary	Put	Written	3400	150	American	2021-01-15
5p Ordinary	Put	Written	900	150	American	2021-01-15
5p Ordinary	Call	Purchased	2500	155	American	2021-01-15
5p Ordinary	Put	Written	4700	155	American	2021-01-15
5p Ordinary	Put	Written	5900	155	American	2021-01-15
5p Ordinary	Put	Written	900	155	American	2021-01-15
5p Ordinary	Put	Written	400	155	American	2021-01-15
5p Ordinary	Put	Written	5000	160	American	2021-01-15
5p Ordinary	Put	Written	500	160	American	2021-01-15
5p Ordinary	Put	Written	43500	160	American	2021-01-15
5p Ordinary	Put	Written	2500	160	American	2021-01-15
5p Ordinary	Put	Written	1000	165	American	2021-01-15
5p Ordinary	Put	Written	200	165	American	2021-01-15
5p Ordinary	Put	Written	18500	165	American	2021-01-15
5p Ordinary	Call	Written	200	170	American	2021-01-15
5p Ordinary	Call	Written	12700	170	American	2021-01-15
5p Ordinary	Call	Written	2200	170	American	2021-01-15
5p Ordinary	Call	Written	1900	170	American	2021-01-15
5p Ordinary	Put	Written	100	170	American	2021-01-15
5p Ordinary	Put	Written	1500	170	American	2021-01-15
5p Ordinary	Put	Purchased	1000	180	American	2021-01-15
5p Ordinary	Put	Purchased	12000	185	American	2021-01-15
5p Ordinary	Put	Purchased	100	185	American	2021-01-15
5p Ordinary	Put	Purchased	1000	190	American	2021-01-15
5p Ordinary	Call	Purchased	500	195	American	2021-01-15
5p Ordinary	Call	Purchased	600	195	American	2021-01-15
5p Ordinary	Call	Purchased	2400	195	American	2021-01-15
5p Ordinary	Put	Purchased	3900	195	American	2021-01-15
5p Ordinary	Call	Purchased	2400	200	American	2021-01-15
5p Ordinary	Call	Written	7400	200	American	2021-01-15
5p Ordinary	Call	Purchased	2100	200	American	2021-01-15
5p Ordinary	Call	Written	27700	230	American	2021-01-15
5p Ordinary	Call	Written	2000	230	American	2021-01-15
5p Ordinary	Call	Written	200	230	American	2021-01-15
5p Ordinary	Call	Written	5000	240	American	2021-01-15
5p Ordinary	Call	Purchased	100	100	American	2020-01-17
5p Ordinary	Put	Written	100	100	American	2020-01-17
5p Ordinary	Put	Written	500	100	American	2020-01-17
5p Ordinary	Put	Purchased	500	100	American	2020-01-17
5p Ordinary	Put	Purchased	1000	105	American	2020-01-17
5p Ordinary	Put	Written	1500	105	American	2020-01-17
5p Ordinary	Call	Written	1000	110	American	2020-01-17
5p Ordinary	Put	Written	400	110	American	2020-01-17
5p Ordinary	Put	Written	500	110	American	2020-01-17
5p Ordinary	Put	Written	2700	110	American	2020-01-17
5p Ordinary	Call	Purchased	100	115	American	2020-01-17
5p Ordinary	Put	Purchased	1200	115	American	2020-01-17
5p Ordinary	Put	Purchased	500	115	American	2020-01-17
5p Ordinary	Put	Written	1200	115	American	2020-01-17
5p Ordinary	Call	Purchased	600	120	American	2020-01-17
5p Ordinary	Put	Purchased	100	120	American	2020-01-17
5p Ordinary	Put	Purchased	1200	125	American	2020-01-17
5p Ordinary	Put	Written	100	125	American	2020-01-17
5p Ordinary	Put	Written	100	130	American	2020-01-17
5p Ordinary	Put	Written	1300	130	American	2020-01-17
5p Ordinary	Put	Purchased	800	130	American	2020-01-17
5p Ordinary	Put	Purchased	1200	135	American	2020-01-17
5p Ordinary	Call	Written	1000	140	American	2020-01-17
5p Ordinary	Call	Purchased	1000	140	American	2020-01-17
5p Ordinary	Call	Written	200	140	American	2020-01-17
5p Ordinary	Put	Written	100	140	American	2020-01-17
5p Ordinary	Put	Written	1700	140	American	2020-01-17
5p Ordinary	Put	Written	300	140	American	2020-01-17
5p Ordinary	Put	Written	7900	145	American	2020-01-17
5p Ordinary	Put	Written	100	145	American	2020-01-17
5p Ordinary	Call	Written	500	150	American	2020-01-17
5p Ordinary	Put	Purchased	2100	150	American	2020-01-17
5p Ordinary	Put	Written	400	150	American	2020-01-17
5p Ordinary	Put	Purchased	1100	155	American	2020-01-17
5p Ordinary	Put	Purchased	500	155	American	2020-01-17
5p Ordinary	Call	Written	500	160	American	2020-01-17
5p Ordinary	Call	Purchased	300	160	American	2020-01-17
5p Ordinary	Put	Purchased	100	160	American	2020-01-17
5p Ordinary	Put	Written	5700	160	American	2020-01-17
5p Ordinary	Put	Written	200	160	American	2020-01-17
5p Ordinary	Put	Purchased	200	160	American	2020-01-17
5p Ordinary	Call	Written	500	165	American	2020-01-17
5p Ordinary	Put	Written	500	165	American	2020-01-17
5p Ordinary	Put	Purchased	100	165	American	2020-01-17
5p Ordinary	Put	Purchased	400	165	American	2020-01-17
5p Ordinary	Put	Purchased	800	165	American	2020-01-17
5p Ordinary	Put	Purchased	100	165	American	2020-01-17
5p Ordinary	Call	Written	200	170	American	2020-01-17
5p Ordinary	Call	Written	500	170	American	2020-01-17
5p Ordinary	Call	Purchased	4900	170	American	2020-01-17
5p Ordinary	Put	Purchased	100	170	American	2020-01-17
5p Ordinary	Put	Purchased	1100	170	American	2020-01-17
5p Ordinary	Put	Purchased	100	170	American	2020-01-17
5p Ordinary	Call	Purchased	300	175	American	2020-01-17
5p Ordinary	Call	Purchased	500	175	American	2020-01-17
5p Ordinary	Put	Written	400	175	American	2020-01-17
5p Ordinary	Put	Written	2300	175	American	2020-01-17
5p Ordinary	Put	Written	100	175	American	2020-01-17
5p Ordinary	Call	Purchased	100	180	American	2020-01-17
5p Ordinary	Call	Purchased	6300	180	American	2020-01-17
5p Ordinary	Put	Purchased	200	180	American	2020-01-17
5p Ordinary	Call	Purchased	2300	185	American	2020-01-17
5p Ordinary	Put	Purchased	700	185	American	2020-01-17
5p Ordinary	Call	Purchased	2100	190	American	2020-01-17
5p Ordinary	Call	Purchased	200	190	American	2020-01-17
5p Ordinary	Put	Purchased	300	190	American	2020-01-17
5p Ordinary	Call	Purchased	1500	195	American	2020-01-17
5p Ordinary	Call	Purchased	300	195	American	2020-01-17
5p Ordinary	Call	Written	100	200	American	2020-01-17
5p Ordinary	Call	Written	100	200	American	2020-01-17
5p Ordinary	Call	Purchased	500	200	American	2020-01-17
5p Ordinary	Call	Purchased	200	200	American	2020-01-17
5p Ordinary	Put	Purchased	100	200	American	2020-01-17
5p Ordinary	Call	Written	2200	210	American	2020-01-17
5p Ordinary	Call	Written	2300	210	American	2020-01-17
5p Ordinary	Call	Purchased	100	220	American	2020-01-17
5p Ordinary	Call	Purchased	400	220	American	2020-01-17
5p Ordinary	Call	Purchased	400	220	American	2020-01-17
5p Ordinary	Call	Purchased	500	240	American	2020-01-17
5p Ordinary	Call	Purchased	1200	240	American	2020-01-17
5p Ordinary	Put	Purchased	100	65	American	2020-01-17
5p Ordinary	Call	Written	1000	70	American	2020-01-17
5p Ordinary	Put	Purchased	400	70	American	2020-01-17
5p Ordinary	Put	Purchased	2200	75	American	2020-01-17
5p Ordinary	Put	Written	300	75	American	2020-01-17
5p Ordinary	Put	Written	100	75	American	2020-01-17
5p Ordinary	Put	Written	4300	80	American	2020-01-17
5p Ordinary	Put	Written	5100	85	American	2020-01-17
5p Ordinary	Put	Written	2000	85	American	2020-01-17
5p Ordinary	Put	Written	200	90	American	2020-01-17
5p Ordinary	Put	Purchased	500	90	American	2020-01-17
5p Ordinary	Put	Purchased	1400	100	American	2019-01-18
5p Ordinary	Call	Purchased	100	105	American	2019-01-18
5p Ordinary	Put	Purchased	3100	105	American	2019-01-18
5p Ordinary	Put	Written	900	105	American	2019-01-18
5p Ordinary	Put	Purchased	200	105	American	2019-01-18
5p Ordinary	Put	Purchased	200	105	American	2019-01-18
5p Ordinary	Put	Purchased	1000	110	American	2019-01-18
5p Ordinary	Put	Purchased	100	110	American	2019-01-18
5p Ordinary	Put	Purchased	100	110	American	2019-01-18
5p Ordinary	Put	Written	200	110	American	2019-01-18
5p Ordinary	Call	Written	100	115	American	2019-01-18
5p Ordinary	Call	Written	1000	115	American	2019-01-18
5p Ordinary	Put	Written	5100	115	American	2019-01-18
5p Ordinary	Put	Purchased	100	120	American	2019-01-18
5p Ordinary	Put	Written	1200	120	American	2019-01-18
5p Ordinary	Put	Written	2500	120	American	2019-01-18
5p Ordinary	Call	Written	3100	125	American	2019-01-18
5p Ordinary	Call	Purchased	8200	125	American	2019-01-18
5p Ordinary	Call	Written	1800	125	American	2019-01-18
5p Ordinary	Call	Written	2000	125	American	2019-01-18
5p Ordinary	Put	Purchased	100	125	American	2019-01-18
5p Ordinary	Put	Purchased	3900	125	American	2019-01-18
5p Ordinary	Put	Written	26600	125	American	2019-01-18
5p Ordinary	Put	Written	12100	125	American	2019-01-18
5p Ordinary	Put	Purchased	100	125	American	2019-01-18
5p Ordinary	Put	Purchased	4000	125	American	2019-01-18
5p Ordinary	Put	Purchased	8000	125	American	2019-01-18
5p Ordinary	Call	Purchased	3100	130	American	2019-01-18
5p Ordinary	Call	Written	8200	130	American	2019-01-18
5p Ordinary	Call	Purchased	1800	130	American	2019-01-18
5p Ordinary	Call	Purchased	2000	130	American	2019-01-18
5p Ordinary	Put	Purchased	200	130	American	2019-01-18
5p Ordinary	Put	Written	500	130	American	2019-01-18
5p Ordinary	Put	Purchased	8500	130	American	2019-01-18
5p Ordinary	Put	Written	1300	130	American	2019-01-18
5p Ordinary	Call	Written	400	135	American	2019-01-18
5p Ordinary	Call	Written	100	135	American	2019-01-18
5p Ordinary	Put	Written	1200	135	American	2019-01-18
5p Ordinary	Put	Purchased	200	135	American	2019-01-18
5p Ordinary	Put	Written	9100	135	American	2019-01-18
5p Ordinary	Put	Written	3000	135	American	2019-01-18
5p Ordinary	Put	Written	400	135	American	2019-01-18
5p Ordinary	Put	Purchased	4000	135	American	2019-01-18
5p Ordinary	Put	Purchased	2000	135	American	2019-01-18
5p Ordinary	Call	Written	200	140	American	2019-01-18
5p Ordinary	Put	Written	200	140	American	2019-01-18
5p Ordinary	Put	Written	4600	140	American	2019-01-18
5p Ordinary	Put	Written	9100	140	American	2019-01-18
5p Ordinary	Put	Purchased	200	140	American	2019-01-18
5p Ordinary	Put	Purchased	1000	140	American	2019-01-18
5p Ordinary	Call	Purchased	4000	145	American	2019-01-18
5p Ordinary	Call	Written	1300	145	American	2019-01-18
5p Ordinary	Put	Purchased	500	145	American	2019-01-18
5p Ordinary	Put	Purchased	800	145	American	2019-01-18
5p Ordinary	Put	Written	1800	145	American	2019-01-18
5p Ordinary	Put	Written	200	145	American	2019-01-18
5p Ordinary	Call	Written	400	150	American	2019-01-18
5p Ordinary	Call	Written	100	150	American	2019-01-18
5p Ordinary	Put	Purchased	300	150	American	2019-01-18
5p Ordinary	Put	Purchased	700	150	American	2019-01-18
5p Ordinary	Put	Written	20800	150	American	2019-01-18
5p Ordinary	Put	Written	16900	150	American	2019-01-18
5p Ordinary	Put	Written	200	150	American	2019-01-18
5p Ordinary	Put	Purchased	100	150	American	2019-01-18
5p Ordinary	Call	Written	500	155	American	2019-01-18
5p Ordinary	Call	Written	100	155	American	2019-01-18
5p Ordinary	Put	Purchased	100	155	American	2019-01-18
5p Ordinary	Put	Purchased	3000	155	American	2019-01-18
5p Ordinary	Put	Written	1000	155	American	2019-01-18
5p Ordinary	Put	Purchased	2400	155	American	2019-01-18
5p Ordinary	Put	Purchased	100	155	American	2019-01-18
5p Ordinary	Call	Written	500	160	American	2019-01-18
5p Ordinary	Call	Written	1200	160	American	2019-01-18
5p Ordinary	Call	Written	700	160	American	2019-01-18
5p Ordinary	Call	Written	100	160	American	2019-01-18
5p Ordinary	Call	Written	1000	160	American	2019-01-18
5p Ordinary	Call	Written	300	160	American	2019-01-18
5p Ordinary	Put	Purchased	100	160	American	2019-01-18
5p Ordinary	Put	Purchased	2700	160	American	2019-01-18
5p Ordinary	Put	Written	1500	160	American	2019-01-18
5p Ordinary	Put	Purchased	3600	160	American	2019-01-18
5p Ordinary	Put	Purchased	700	160	American	2019-01-18
5p Ordinary	Put	Purchased	2000	160	American	2019-01-18
5p Ordinary	Put	Purchased	1800	160	American	2019-01-18
5p Ordinary	Call	Written	1100	165	American	2019-01-18
5p Ordinary	Call	Written	2600	165	American	2019-01-18
5p Ordinary	Call	Written	100	165	American	2019-01-18
5p Ordinary	Call	Written	5000	165	American	2019-01-18
5p Ordinary	Put	Purchased	200	165	American	2019-01-18
5p Ordinary	Put	Purchased	2100	165	American	2019-01-18
5p Ordinary	Put	Written	27300	165	American	2019-01-18
5p Ordinary	Put	Purchased	25700	165	American	2019-01-18
5p Ordinary	Put	Purchased	200	165	American	2019-01-18
5p Ordinary	Put	Purchased	2100	165	American	2019-01-18
5p Ordinary	Call	Written	100	170	American	2019-01-18
5p Ordinary	Call	Written	1000	170	American	2019-01-18
5p Ordinary	Call	Written	9800	170	American	2019-01-18
5p Ordinary	Call	Written	2800	170	American	2019-01-18
5p Ordinary	Call	Written	500	170	American	2019-01-18
5p Ordinary	Put	Purchased	1100	170	American	2019-01-18
5p Ordinary	Put	Purchased	26300	170	American	2019-01-18
5p Ordinary	Put	Purchased	7600	170	American	2019-01-18
5p Ordinary	Put	Purchased	300	170	American	2019-01-18
5p Ordinary	Put	Purchased	700	170	American	2019-01-18
5p Ordinary	Call	Written	400	175	American	2019-01-18
5p Ordinary	Call	Written	6100	175	American	2019-01-18
5p Ordinary	Call	Written	7400	175	American	2019-01-18
5p Ordinary	Call	Written	8500	175	American	2019-01-18
5p Ordinary	Call	Written	100	175	American	2019-01-18
5p Ordinary	Call	Written	100	175	American	2019-01-18
5p Ordinary	Put	Written	800	175	American	2019-01-18
5p Ordinary	Put	Written	200	175	American	2019-01-18
5p Ordinary	Call	Purchased	500	180	American	2019-01-18
5p Ordinary	Call	Written	800	180	American	2019-01-18
5p Ordinary	Call	Written	4600	180	American	2019-01-18
5p Ordinary	Call	Written	53200	180	American	2019-01-18
5p Ordinary	Call	Written	74000	180	American	2019-01-18
5p Ordinary	Call	Written	200	180	American	2019-01-18
5p Ordinary	Call	Written	900	180	American	2019-01-18
5p Ordinary	Put	Written	2200	180	American	2019-01-18
5p Ordinary	Put	Written	300	180	American	2019-01-18
5p Ordinary	Put	Written	2400	180	American	2019-01-18
5p Ordinary	Put	Written	100	180	American	2019-01-18
5p Ordinary	Put	Purchased	500	180	American	2019-01-18
5p Ordinary	Put	Written	300	180	American	2019-01-18
5p Ordinary	Call	Purchased	1100	185	American	2019-01-18
5p Ordinary	Call	Purchased	600	185	American	2019-01-18
5p Ordinary	Call	Written	11200	185	American	2019-01-18
5p Ordinary	Call	Written	50600	185	American	2019-01-18
5p Ordinary	Call	Purchased	400	185	American	2019-01-18
5p Ordinary	Call	Purchased	1200	185	American	2019-01-18
5p Ordinary	Put	Written	500	185	American	2019-01-18
5p Ordinary	Put	Written	400	185	American	2019-01-18
5p Ordinary	Put	Written	100	185	American	2019-01-18
5p Ordinary	Put	Written	200	185	American	2019-01-18
5p Ordinary	Call	Written	200	190	American	2019-01-18
5p Ordinary	Call	Purchased	8600	190	American	2019-01-18
5p Ordinary	Call	Purchased	52400	190	American	2019-01-18
5p Ordinary	Call	Purchased	72200	190	American	2019-01-18
5p Ordinary	Call	Written	200	190	American	2019-01-18
5p Ordinary	Call	Purchased	1000	190	American	2019-01-18
5p Ordinary	Call	Written	600	190	American	2019-01-18
5p Ordinary	Put	Purchased	100	190	American	2019-01-18
5p Ordinary	Call	Purchased	800	195	American	2019-01-18
5p Ordinary	Call	Purchased	17500	195	American	2019-01-18
5p Ordinary	Call	Purchased	37500	195	American	2019-01-18
5p Ordinary	Call	Written	100	195	American	2019-01-18
5p Ordinary	Call	Purchased	100	195	American	2019-01-18
5p Ordinary	Put	Purchased	100	195	American	2019-01-18
5p Ordinary	Call	Purchased	900	200	American	2019-01-18
5p Ordinary	Call	Purchased	700	200	American	2019-01-18
5p Ordinary	Call	Written	68800	200	American	2019-01-18
5p Ordinary	Call	Purchased	26700	200	American	2019-01-18
5p Ordinary	Call	Purchased	300	200	American	2019-01-18
5p Ordinary	Call	Purchased	100	200	American	2019-01-18
5p Ordinary	Call	Written	500	205	American	2019-01-18
5p Ordinary	Call	Written	1000	205	American	2019-01-18
5p Ordinary	Call	Written	100	205	American	2019-01-18
5p Ordinary	Call	Purchased	300	210	American	2019-01-18
5p Ordinary	Call	Purchased	2600	210	American	2019-01-18
5p Ordinary	Call	Purchased	700	210	American	2019-01-18
5p Ordinary	Call	Written	400	215	American	2019-01-18
5p Ordinary	Call	Written	300	215	American	2019-01-18
5p Ordinary	Call	Written	800	215	American	2019-01-18
5p Ordinary	Call	Written	100	215	American	2019-01-18
5p Ordinary	Call	Written	400	215	American	2019-01-18
5p Ordinary	Call	Purchased	100	220	American	2019-01-18
5p Ordinary	Call	Purchased	2800	220	American	2019-01-18
5p Ordinary	Call	Written	100	230	American	2019-01-18
5p Ordinary	Put	Purchased	900	70	American	2019-01-18
5p Ordinary	Put	Purchased	1600	70	American	2019-01-18
5p Ordinary	Put	Purchased	300	75	American	2019-01-18
5p Ordinary	Put	Purchased	100	80	American	2019-01-18
5p Ordinary	Put	Purchased	300	80	American	2019-01-18
5p Ordinary	Put	Purchased	1400	80	American	2019-01-18
5p Ordinary	Put	Purchased	100	80	American	2019-01-18
5p Ordinary	Call	Written	100	85	American	2019-01-18
5p Ordinary	Put	Written	100	90	American	2019-01-18
5p Ordinary	Put	Written	100	90	American	2019-01-18
5p Ordinary	Put	Written	100	90	American	2019-01-18
5p Ordinary	Put	Purchased	4000	95	American	2019-01-18
5p Ordinary	Put	Purchased	500	120	American	2019-04-18
5p Ordinary	Put	Purchased	500	125	American	2019-04-18
5p Ordinary	Put	Purchased	200	150	American	2019-04-18
5p Ordinary	Put	Purchased	1700	150	American	2019-04-18
5p Ordinary	Put	Purchased	1900	150	American	2019-04-18
5p Ordinary	Put	Written	300	150	American	2019-04-18
5p Ordinary	Put	Written	1000	155	American	2019-04-18
5p Ordinary	Put	Purchased	700	155	American	2019-04-18
5p Ordinary	Put	Purchased	20700	155	American	2019-04-18
5p Ordinary	Put	Purchased	100	155	American	2019-04-18
5p Ordinary	Put	Written	1000	155	American	2019-04-18
5p Ordinary	Call	Purchased	1000	160	American	2019-04-18
5p Ordinary	Put	Written	7400	160	American	2019-04-18
5p Ordinary	Put	Written	500	160	American	2019-04-18
5p Ordinary	Put	Written	3200	165	American	2019-04-18
5p Ordinary	Call	Purchased	100	170	American	2019-04-18
5p Ordinary	Put	Purchased	100	170	American	2019-04-18
5p Ordinary	Put	Written	8800	170	American	2019-04-18
5p Ordinary	Put	Written	9500	170	American	2019-04-18
5p Ordinary	Call	Purchased	2500	175	American	2019-04-18
5p Ordinary	Call	Written	100	175	American	2019-04-18
5p Ordinary	Call	Purchased	200	180	American	2019-04-18
5p Ordinary	Call	Written	1000	180	American	2019-04-18
5p Ordinary	Put	Purchased	5000	180	American	2019-04-18
5p Ordinary	Call	Purchased	5000	185	American	2019-04-18
5p Ordinary	Call	Written	1000	185	American	2019-04-18
5p Ordinary	Call	Written	200	190	American	2019-04-18
5p Ordinary	Call	Written	100	190	American	2019-04-18
5p Ordinary	Call	Purchased	5100	190	American	2019-04-18
5p Ordinary	Call	Purchased	1000	190	American	2019-04-18
5p Ordinary	Call	Purchased	2000	195	American	2019-04-18
5p Ordinary	Call	Written	100	200	American	2019-04-18
5p Ordinary	Call	Purchased	8900	200	American	2019-04-18
5p Ordinary	Put	Written	1000	120	American	2019-07-19
5p Ordinary	Call	Written	2700	130	American	2019-07-19
5p Ordinary	Put	Written	1000	140	American	2019-07-19
5p Ordinary	Put	Written	100	145	American	2019-07-19
5p Ordinary	Put	Purchased	2000	145	American	2019-07-19
5p Ordinary	Put	Purchased	5000	150	American	2019-07-19
5p Ordinary	Put	Written	1000	150	American	2019-07-19
5p Ordinary	Put	Written	700	155	American	2019-07-19
5p Ordinary	Put	Written	9000	155	American	2019-07-19
5p Ordinary	Put	Written	4300	160	American	2019-07-19
5p Ordinary	Put	Written	300	160	American	2019-07-19
5p Ordinary	Call	Purchased	2500	165	American	2019-07-19
5p Ordinary	Put	Purchased	100	165	American	2019-07-19
5p Ordinary	Put	Written	9300	165	American	2019-07-19
5p Ordinary	Call	Purchased	100	170	American	2019-07-19
5p Ordinary	Call	Purchased	100	170	American	2019-07-19
5p Ordinary	Call	Purchased	100	170	American	2019-07-19
5p Ordinary	Call	Purchased	1000	170	American	2019-07-19
5p Ordinary	Call	Purchased	100	190	American	2019-07-19
5p Ordinary	Call	Purchased	3000	200	American	2019-07-19
5p Ordinary	Call	Purchased	300	220	American	2019-07-19
5p Ordinary	Call	Written	2000	220	American	2019-07-19
5p Ordinary	Put	Purchased	100	120	American	2018-12-21
5p Ordinary	Put	Written	9700	120	American	2018-12-21
5p Ordinary	Put	Purchased	900	120	American	2018-12-21
5p Ordinary	Put	Purchased	1200	120	American	2018-12-21
5p Ordinary	Put	Written	5700	125	American	2018-12-21
5p Ordinary	Call	Written	2700	130	American	2018-12-21
5p Ordinary	Call	Purchased	2700	130	American	2018-12-21
5p Ordinary	Put	Purchased	300	135	American	2018-12-21
5p Ordinary	Put	Written	800	135	American	2018-12-21
5p Ordinary	Put	Purchased	200	135	American	2018-12-21
5p Ordinary	Put	Purchased	300	135	American	2018-12-21
5p Ordinary	Put	Written	10700	140	American	2018-12-21
5p Ordinary	Put	Purchased	8600	145	American	2018-12-21
5p Ordinary	Put	Purchased	100	145	American	2018-12-21
5p Ordinary	Call	Written	700	150	American	2018-12-21
5p Ordinary	Call	Written	1300	150	American	2018-12-21
5p Ordinary	Put	Purchased	12900	150	American	2018-12-21
5p Ordinary	Put	Written	20400	150	American	2018-12-21
5p Ordinary	Put	Written	100	150	American	2018-12-21
5p Ordinary	Call	Purchased	700	155	American	2018-12-21
5p Ordinary	Call	Purchased	1300	155	American	2018-12-21
5p Ordinary	Put	Purchased	100	155	American	2018-12-21
5p Ordinary	Put	Purchased	31900	155	American	2018-12-21
5p Ordinary	Put	Written	15700	155	American	2018-12-21
5p Ordinary	Put	Purchased	1000	155	American	2018-12-21
5p Ordinary	Put	Purchased	100	155	American	2018-12-21
5p Ordinary	Put	Purchased	300	160	American	2018-12-21
5p Ordinary	Put	Purchased	12500	160	American	2018-12-21
5p Ordinary	Put	Purchased	23500	160	American	2018-12-21
5p Ordinary	Put	Purchased	100	160	American	2018-12-21
5p Ordinary	Put	Purchased	1100	162.5	American	2018-12-21
5p Ordinary	Call	Written	100	165	American	2018-12-21
5p Ordinary	Call	Written	19100	165	American	2018-12-21
5p Ordinary	Put	Purchased	200	165	American	2018-12-21
5p Ordinary	Put	Purchased	1600	165	American	2018-12-21
5p Ordinary	Put	Written	22200	165	American	2018-12-21
5p Ordinary	Put	Written	12900	165	American	2018-12-21
5p Ordinary	Put	Purchased	100	165	American	2018-12-21
5p Ordinary	Put	Purchased	1000	165	American	2018-12-21
5p Ordinary	Put	Written	1000	165	American	2018-12-21
5p Ordinary	Put	Written	1500	167.5	American	2018-12-21
5p Ordinary	Put	Purchased	700	167.5	American	2018-12-21
5p Ordinary	Call	Purchased	100	170	American	2018-12-21
5p Ordinary	Put	Purchased	1500	170	American	2018-12-21
5p Ordinary	Put	Purchased	1200	170	American	2018-12-21
5p Ordinary	Put	Written	10000	170	American	2018-12-21
5p Ordinary	Put	Purchased	25700	170	American	2018-12-21
5p Ordinary	Put	Written	300	170	American	2018-12-21
5p Ordinary	Put	Written	700	170	American	2018-12-21
5p Ordinary	Call	Written	400	172.5	American	2018-12-21
5p Ordinary	Call	Purchased	9900	172.5	American	2018-12-21
5p Ordinary	Call	Purchased	400	172.5	American	2018-12-21
5p Ordinary	Put	Purchased	6300	172.5	American	2018-12-21
5p Ordinary	Call	Purchased	700	175	American	2018-12-21
5p Ordinary	Call	Purchased	31500	175	American	2018-12-21
5p Ordinary	Call	Purchased	19800	175	American	2018-12-21
5p Ordinary	Call	Written	600	175	American	2018-12-21
5p Ordinary	Put	Purchased	3200	175	American	2018-12-21
5p Ordinary	Put	Purchased	1100	175	American	2018-12-21
5p Ordinary	Put	Purchased	1500	175	American	2018-12-21
5p Ordinary	Call	Written	100	177.5	American	2018-12-21
5p Ordinary	Call	Purchased	16000	177.5	American	2018-12-21
5p Ordinary	Call	Written	400	177.5	American	2018-12-21
5p Ordinary	Call	Purchased	60000	180	American	2018-12-21
5p Ordinary	Call	Written	4900	180	American	2018-12-21
5p Ordinary	Call	Purchased	14500	180	American	2018-12-21
5p Ordinary	Call	Written	5400	180	American	2018-12-21
5p Ordinary	Call	Purchased	100	180	American	2018-12-21
5p Ordinary	Call	Purchased	100	180	American	2018-12-21
5p Ordinary	Put	Purchased	52500	180	American	2018-12-21
5p Ordinary	Put	Purchased	300	180	American	2018-12-21
5p Ordinary	Put	Written	300	180	American	2018-12-21
5p Ordinary	Put	Written	100	180	American	2018-12-21
5p Ordinary	Call	Purchased	10000	185	American	2018-12-21
5p Ordinary	Call	Purchased	6900	185	American	2018-12-21
5p Ordinary	Call	Purchased	58600	185	American	2018-12-21
5p Ordinary	Call	Purchased	13000	185	American	2018-12-21
5p Ordinary	Call	Purchased	100	185	American	2018-12-21
5p Ordinary	Call	Purchased	3000	185	American	2018-12-21
5p Ordinary	Call	Purchased	300	185	American	2018-12-21
5p Ordinary	Call	Purchased	300	187.5	American	2018-12-21
5p Ordinary	Call	Purchased	200	187.5	American	2018-12-21
5p Ordinary	Call	Purchased	1000	187.5	American	2018-12-21
5p Ordinary	Call	Purchased	500	190	American	2018-12-21
5p Ordinary	Call	Purchased	9300	190	American	2018-12-21
5p Ordinary	Call	Purchased	6800	190	American	2018-12-21
5p Ordinary	Call	Purchased	200	190	American	2018-12-21
5p Ordinary	Call	Purchased	400	190	American	2018-12-21
5p Ordinary	Call	Purchased	800	192.5	American	2018-12-21
5p Ordinary	Call	Purchased	15500	192.5	American	2018-12-21
5p Ordinary	Call	Purchased	1000	192.5	American	2018-12-21
5p Ordinary	Call	Purchased	100	192.5	American	2018-12-21
5p Ordinary	Call	Purchased	1000	197.5	American	2018-12-21
5p Ordinary	Call	Written	700	200	American	2018-12-21
5p Ordinary	Call	Written	3500	210	American	2018-12-21
5p Ordinary	Call	Written	600	210	American	2018-12-21
5p Ordinary	Call	Written	2000	210	American	2018-12-21
5p Ordinary	Call	Written	27300	210	American	2018-12-21
5p Ordinary	Put	Purchased	100	147	American	2018-12-28
5p Ordinary	Put	Purchased	300	150	American	2018-12-28
5p Ordinary	Put	Purchased	100	160	American	2018-12-28
5p Ordinary	Put	Purchased	100	160	American	2018-12-28
5p Ordinary	Put	Written	500	167.5	American	2018-12-28
5p Ordinary	Put	Written	100	170	American	2018-12-28
5p Ordinary	Call	Written	300	210	American	2018-12-28

3. AGREEMENTS TO PURCHASE OR SELL ETC.

Full details should be given so that the nature of the interest or position can be fully understood:

It is not necessary to provide details on a Supplemental Form (Open Positions) with regard to cash-settled derivatives.

The currency of all prices and other monetary amounts should be stated.

The Panel's Market Surveillance Unit is available for consultation in relation to the Code's disclosure requirements on +44 (0)20 7638 0129.

The Code can be viewed on the Panel's website at www.thetakeoverpanel.org.uk.

This information is provided by RNS, the news service of the London Stock Exchange. RNS is approved by the Financial Conduct Authority to act as a Primary Information Provider in the United Kingdom. Terms and conditions relating to the use and distribution of this information may apply. For further information, please contact rns@lseg.com or visit www.rns.com.

END

FEOUKOSRWOAUAAA

Date		Source	Headline
8th Jan 2019	5:30 pm	GNW	Director/PDMR Shareholding
8th Jan 2019	3:20 pm	RNS	Form 8.3 - Shire plc
8th Jan 2019	3:19 pm	RNS	Form 8.3 - Takeda Pharmaceutical Company Limited
8th Jan 2019	3:13 pm	RNS	Form 8.3 - Shire plc
8th Jan 2019	3:07 pm	RNS	Form 8.5 (EPT/NON-RI)
8th Jan 2019	2:28 pm	RNS	Form 8.5 (EPT/RI) - Replacement of Shire
8th Jan 2019	2:23 pm	RNS	Form 8.5 (EPT/RI) - Replacement of Shire
8th Jan 2019	2:21 pm	RNS	Form 8.5 (EPT/RI) - Replacement of Shire
8th Jan 2019	1:57 pm	RNS	Form 8.3 - Takeda Pharmaceutical Company Limited
8th Jan 2019	1:27 pm	RNS	Form 8.3 - Shire plc
8th Jan 2019	12:31 pm	RNS	Form 8.3 - Takeda Pharmaceutical Company Limited
8th Jan 2019	12:29 pm	RNS	Form 8.3 - Takeda Pharmaceutical
8th Jan 2019	12:27 pm	RNS	Form 8.3 - Shire plc
8th Jan 2019	11:42 am	RNS	Form 8.5 (EPT/NON-RI)
8th Jan 2019	11:33 am	RNS	Form 8.5 (EPT/NON-RI)- Shire Plc
8th Jan 2019	10:49 am	RNS	Form 8.5 (EPT/RI)
8th Jan 2019	10:41 am	RNS	Form 8.3 - Takeda Pharmaceutical Company Limited
8th Jan 2019	10:26 am	RNS	Form 8.5 (EPT/RI)- Shire plc
8th Jan 2019	9:51 am	RNS	Form 8.3 - Shire Plc
8th Jan 2019	8:44 am	RNS	Form 8.5 (EPT/RI) - SHIRE PLC
8th Jan 2019	7:00 am	RNS	Form 8.3 - Takeda Pharmaceutical Company Limited
8th Jan 2019	7:00 am	GNW	Scheme becomes effective
7th Jan 2019	5:00 pm	GNW	Holding(s) in Company
7th Jan 2019	3:42 pm	RNS	Form 8.5 (EPT/RI) - Amendment
7th Jan 2019	3:20 pm	RNS	Form 8.3 - Shire plc
7th Jan 2019	3:02 pm	RNS	Form 8.3 - Shire plc
7th Jan 2019	3:00 pm	RNS	Form 8.5 (EPT/NON-RI)
7th Jan 2019	3:00 pm	RNS	Form 8.3 - Shire plc
7th Jan 2019	2:59 pm	RNS	Form 8.3 - Takeda Pharmaceutical
7th Jan 2019	2:50 pm	PRN	Form 8.3 - Shire Plc
7th Jan 2019	2:49 pm	RNS	Form 8.3 - Shire plc
7th Jan 2019	2:47 pm	RNS	Form 8.3 - Takeda Pharmaceutical Company Limited
7th Jan 2019	2:45 pm	BUS	Form 8.3 - Shire plc
7th Jan 2019	1:55 pm	RNS	Form 8.3 - Takeda Pharmaceutical Company Limited
7th Jan 2019	1:54 pm	RNS	Form 8.3 - Shire plc
7th Jan 2019	1:39 pm	RNS	Form 8.3 - [Shire Plc]
7th Jan 2019	1:32 pm	RNS	Form 8.5 (EPT/RI) - Replacement of Shire
7th Jan 2019	1:29 pm	RNS	Form 8.5 (EPT/RI) - Replacement of Shire
7th Jan 2019	12:57 pm	RNS	Form 8.3 - Takeda Pharmaceutical Company Limited
7th Jan 2019	12:56 pm	RNS	Form 8.3 - Shire plc
7th Jan 2019	12:42 pm	RNS	Form 8.5 (EPT/NON-RI)
7th Jan 2019	11:52 am	RNS	Form 8.3 - Takeda Pharmaceutical Company Limited
7th Jan 2019	11:43 am	BUS	Form 8.3 - SHIRE PLC
7th Jan 2019	11:30 am	RNS	Form 8.3 - Takeda Pharmaceutical Company Limited
7th Jan 2019	11:27 am	RNS	Form 8.3 - Shire plc
7th Jan 2019	11:01 am	RNS	Form 8.5 (EPT/RI)- Shire plc
7th Jan 2019	10:59 am	RNS	Form 8.5 (EPT/NON-RI)- Shire Plc
7th Jan 2019	10:35 am	RNS	Form 8.5 - Shire plc
7th Jan 2019	10:16 am	RNS	Form 8.5 (EPT/RI) - SHIRE PLC
7th Jan 2019	10:13 am	RNS	Form 8.5 (EPT/RI) - Amendment

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