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Form 8.3 - Shire PLC

24 Dec 2018 13:00

RNS Number : 4682L

Citadel Group

24 December 2018

FORM 8.3

PUBLIC OPENING POSITION DISCLOSURE/DEALING DISCLOSURE BY

A PERSON WITH INTERESTS IN RELEVANT SECURITIES REPRESENTING 1%

OR MORE

Rule 8.3 of the Takeover Code (the "Code")

1. KEY INFORMATION

(a) Full name of discloser:	Citadel Group
(b) Owner or controller of interests and short positions disclosed, if different from 1(a): The naming of nominee or vehicle companies is insufficient. For a trust, the trustee(s), settlor and beneficiaries must be named.
(c) Name of offeror/offeree in relation to whose relevant securities this form relates: Use a separate form for each offeror/offeree	SHIRE PLC
(d) If an exempt fund manager connected with an offeror/offeree, state this and specify identity of offeror/offeree:
(e) Date position held/dealing undertaken: For an opening position disclosure, state the latest practicable date prior to the disclosure	21 December, 2018
(f) In addition to the company in 1(c) above, is the discloser making disclosures in respect of any other party to the offer? If it is a cash offer or possible cash offer, state "N/A"	TAKEDA PHARMACEUTICAL COMPANY LIMITED

2. POSITIONS OF THE PERSON MAKING THE DISCLOSURE

If there are positions or rights to subscribe to disclose in more than one class of relevant securities of the offeror or offeree named in 1(c), copy table 2(a) or (b) (as appropriate) for each additional class of relevant security.

(a) Interests and short positions in the relevant securities of the offeror or offeree to which the disclosure relates following the dealing (if any)

Class of relevant security:	Common Stock ISIN JE00B2QKY057
	Interests		Short Positions
	Number	%	Number	%
(1) Relevant securities owned and/or controlled:	8,527,945	0.93	0	0.00
(2) Cash-settled derivatives:	0	0.00	1	0.00
(3) Stock-settled derivatives (including options) and agreements to purchase/sell:	626,000	0.07	33,000	0.00
TOTAL:	9,153,945	1.00	33,001	0.00

All interests and all short positions should be disclosed.

Details of any open stock-settled derivative positions (including traded options), or agreements to purchase or sell relevant securities, should be given on a Supplemental Form 8 (Open Positions).

(b) Rights to subscribe for new securities (including directors' and other employee options)

Class of relevant security in relation to which subscription right exists:
Details, including nature of the rights concerned and relevant percentages:

3. DEALINGS (IF ANY) BY THE PERSON MAKING THE DISCLOSURE

Where there have been dealings in more than one class of relevant securities of the offeror or offeree named in 1(c), copy table 3(a), (b), (c) or (d) (as appropriate) for each additional class of relevant security dealt in.

The currency of all prices and other monetary amounts should be stated.

(a) Purchases and sales

Class of relevant security ISIN JE00B2QKY057	Purchase/sale	Number of securities	Price per unit
Common Stock	Purchase	460	44.6 GBP
Common Stock	Purchase	300	44.605 GBP
Common Stock	Purchase	160	44.61 GBP
Common Stock	Purchase	673	44.615 GBP
Common Stock	Purchase	468	44.62 GBP
Common Stock	Purchase	287	44.62125 GBP
Common Stock	Purchase	260	44.6225 GBP
Common Stock	Purchase	1,056	44.625 GBP
Common Stock	Purchase	268	44.626 GBP
Common Stock	Purchase	1,077	44.62625 GBP
Common Stock	Purchase	959	44.63 GBP
Common Stock	Purchase	330	44.63125 GBP
Common Stock	Purchase	298	44.6325 GBP
Common Stock	Purchase	486	44.635 GBP
Common Stock	Purchase	430	44.63625 GBP
Common Stock	Purchase	3,463	44.64 GBP
Common Stock	Purchase	2,300	44.64125 GBP
Common Stock	Purchase	2,326	44.645 GBP
Common Stock	Purchase	1,086	44.64625 GBP
Common Stock	Purchase	2,739	44.65 GBP
Common Stock	Purchase	291	44.651 GBP
Common Stock	Purchase	831	44.65125 GBP
Common Stock	Purchase	709	44.6525 GBP
Common Stock	Purchase	671	44.655 GBP
Common Stock	Purchase	246	44.65625 GBP
Common Stock	Purchase	667	44.6575 GBP
Common Stock	Purchase	1,957	44.66 GBP
Common Stock	Purchase	530	44.66125 GBP
Common Stock	Purchase	1	44.6625 GBP
Common Stock	Purchase	3,522	44.665 GBP
Common Stock	Purchase	750	44.66625 GBP
Common Stock	Purchase	1,244	44.6675 GBP
Common Stock	Purchase	5,247	44.67 GBP
Common Stock	Purchase	873	44.67125 GBP
Common Stock	Purchase	1,959	44.6725 GBP
Common Stock	Purchase	330	44.67375 GBP
Common Stock	Purchase	5,687	44.675 GBP
Common Stock	Purchase	363	44.67625 GBP
Common Stock	Purchase	3,221	44.6775 GBP
Common Stock	Purchase	5,961	44.68 GBP
Common Stock	Purchase	367	44.681 GBP
Common Stock	Purchase	875	44.68125 GBP
Common Stock	Purchase	1,717	44.6825 GBP
Common Stock	Purchase	1,198	44.685 GBP
Common Stock	Purchase	940	44.68625 GBP
Common Stock	Purchase	628	44.6875 GBP
Common Stock	Purchase	450	44.68875 GBP
Common Stock	Purchase	1,697	44.69 GBP
Common Stock	Purchase	661	44.69125 GBP
Common Stock	Purchase	500	44.695 GBP
Common Stock	Purchase	400	44.69625 GBP
Common Stock	Purchase	2,426	44.7 GBP
Common Stock	Purchase	647	44.70125 GBP
Common Stock	Purchase	4,584	44.7025 GBP
Common Stock	Purchase	1,653	44.705 GBP
Common Stock	Purchase	370	44.70625 GBP
Common Stock	Purchase	232	44.7075 GBP
Common Stock	Purchase	2,524	44.71 GBP
Common Stock	Purchase	1,013	44.715 GBP
Common Stock	Purchase	344	44.72 GBP
Common Stock	Purchase	341	44.72125 GBP
Common Stock	Purchase	525	44.725 GBP
Common Stock	Purchase	448	44.73 GBP
Common Stock	Purchase	1,327	44.735 GBP
Common Stock	Purchase	2,447	44.74 GBP
Common Stock	Purchase	396	44.7425 GBP
Common Stock	Purchase	1,610	44.745 GBP
Common Stock	Purchase	490	44.74625 GBP
Common Stock	Purchase	365	44.747 GBP
Common Stock	Purchase	1,986	44.75 GBP
Common Stock	Purchase	2,676	44.755 GBP
Common Stock	Purchase	3,469	44.76 GBP
Common Stock	Purchase	499	44.76125 GBP
Common Stock	Purchase	300	44.7625 GBP
Common Stock	Purchase	3,364	44.765 GBP
Common Stock	Purchase	320	44.76625 GBP
Common Stock	Purchase	25	44.7675 GBP
Common Stock	Purchase	2,284	44.77 GBP
Common Stock	Purchase	3,229	44.775 GBP
Common Stock	Purchase	2,959	44.78 GBP
Common Stock	Purchase	245	44.78125 GBP
Common Stock	Purchase	5,568	44.785 GBP
Common Stock	Purchase	5,687	44.79 GBP
Common Stock	Purchase	290	44.79125 GBP
Common Stock	Purchase	5,624	44.795 GBP
Common Stock	Purchase	295	44.79625 GBP
Common Stock	Purchase	622	44.7975 GBP
Common Stock	Purchase	2,522	44.8 GBP
Common Stock	Purchase	2,697	44.8025 GBP
Common Stock	Purchase	21,823	44.805 GBP
Common Stock	Purchase	2,652	44.80625 GBP
Common Stock	Purchase	6,697	44.8075 GBP
Common Stock	Purchase	20,909	44.81 GBP
Common Stock	Purchase	1,162	44.81125 GBP
Common Stock	Purchase	236	44.8125 GBP
Common Stock	Purchase	10,198	44.815 GBP
Common Stock	Purchase	1,166	44.81625 GBP
Common Stock	Purchase	7,916	44.82 GBP
Common Stock	Purchase	497	44.82125 GBP
Common Stock	Purchase	322	44.8225 GBP
Common Stock	Purchase	15,071	44.825 GBP
Common Stock	Purchase	1,081	44.82625 GBP
Common Stock	Purchase	8	44.8275 GBP
Common Stock	Purchase	5,052	44.83 GBP
Common Stock	Purchase	367	44.83125 GBP
Common Stock	Purchase	389	44.8325 GBP
Common Stock	Purchase	7,699	44.835 GBP
Common Stock	Purchase	1,884	44.83625 GBP
Common Stock	Purchase	294	44.837 GBP
Common Stock	Purchase	1,282	44.8375 GBP
Common Stock	Purchase	11,112	44.84 GBP
Common Stock	Purchase	3,000	44.8425 GBP
Common Stock	Purchase	5,060	44.845 GBP
Common Stock	Purchase	360	44.846 GBP
Common Stock	Purchase	1,365	44.8475 GBP
Common Stock	Purchase	3,015	44.85 GBP
Common Stock	Purchase	997	44.85125 GBP
Common Stock	Purchase	345	44.852 GBP
Common Stock	Purchase	275	44.8525 GBP
Common Stock	Purchase	3,307	44.855 GBP
Common Stock	Purchase	704	44.856 GBP
Common Stock	Purchase	584	44.8575 GBP
Common Stock	Purchase	5,080	44.86 GBP
Common Stock	Purchase	763	44.86125 GBP
Common Stock	Purchase	201	44.8625 GBP
Common Stock	Purchase	8,007	44.865 GBP
Common Stock	Purchase	1,040	44.86625 GBP
Common Stock	Purchase	3,353	44.87 GBP
Common Stock	Purchase	547	44.8725 GBP
Common Stock	Purchase	3,181	44.875 GBP
Common Stock	Purchase	1,553	44.87625 GBP
Common Stock	Purchase	5,312	44.88 GBP
Common Stock	Purchase	271	44.881 GBP
Common Stock	Purchase	240	44.88125 GBP
Common Stock	Purchase	9,684	44.885 GBP
Common Stock	Purchase	669	44.88625 GBP
Common Stock	Purchase	360	44.887 GBP
Common Stock	Purchase	1,080	44.8875 GBP
Common Stock	Purchase	330	44.88875 GBP
Common Stock	Purchase	7,693	44.89 GBP
Common Stock	Purchase	360	44.89125 GBP
Common Stock	Purchase	47,163	44.895 GBP
Common Stock	Purchase	245	44.89625 GBP
Common Stock	Purchase	6,195	44.9 GBP
Common Stock	Purchase	728	44.901 GBP
Common Stock	Purchase	944	44.90125 GBP
Common Stock	Purchase	309	44.902 GBP
Common Stock	Purchase	292	44.9025 GBP
Common Stock	Purchase	4,658	44.905 GBP
Common Stock	Purchase	883	44.90625 GBP
Common Stock	Purchase	350	44.9075 GBP
Common Stock	Purchase	245	44.90875 GBP
Common Stock	Purchase	8,835	44.91 GBP
Common Stock	Purchase	266	44.911 GBP
Common Stock	Purchase	1,120	44.91125 GBP
Common Stock	Purchase	1,436	44.9125 GBP
Common Stock	Purchase	6,058	44.915 GBP
Common Stock	Purchase	379	44.91625 GBP
Common Stock	Purchase	1,275	44.9175 GBP
Common Stock	Purchase	7,022	44.92 GBP
Common Stock	Purchase	925	44.921 GBP
Common Stock	Purchase	1,258	44.92125 GBP
Common Stock	Purchase	1,232	44.9225 GBP
Common Stock	Purchase	6,936	44.925 GBP
Common Stock	Purchase	6,448	44.93 GBP
Common Stock	Purchase	414	44.9325 GBP
Common Stock	Purchase	6,114	44.935 GBP
Common Stock	Purchase	260	44.93625 GBP
Common Stock	Purchase	3,083	44.9375 GBP
Common Stock	Purchase	5,072	44.94 GBP
Common Stock	Purchase	310	44.94125 GBP
Common Stock	Purchase	239	44.9425 GBP
Common Stock	Purchase	2,954	44.945 GBP
Common Stock	Purchase	3,647	44.95 GBP
Common Stock	Purchase	305	44.95125 GBP
Common Stock	Purchase	223	44.9525 GBP
Common Stock	Purchase	2,624	44.955 GBP
Common Stock	Purchase	565	44.95625 GBP
Common Stock	Purchase	887	44.9575 GBP
Common Stock	Purchase	2,331	44.96 GBP
Common Stock	Purchase	290	44.96125 GBP
Common Stock	Purchase	10	44.9625 GBP
Common Stock	Purchase	6,029	44.965 GBP
Common Stock	Purchase	2,100	44.96625 GBP
Common Stock	Purchase	2,973	44.97 GBP
Common Stock	Purchase	2,038	44.975 GBP
Common Stock	Purchase	296	44.9775 GBP
Common Stock	Purchase	3,998	44.98 GBP
Common Stock	Purchase	350	44.981 GBP
Common Stock	Purchase	1,193	44.9825 GBP
Common Stock	Purchase	2,137	44.985 GBP
Common Stock	Purchase	676	44.9875 GBP
Common Stock	Purchase	9,778	44.99 GBP
Common Stock	Purchase	721	44.99125 GBP
Common Stock	Purchase	208	44.9925 GBP
Common Stock	Purchase	1,924	44.995 GBP
Common Stock	Purchase	1,198	44.9975 GBP
Common Stock	Purchase	8,717	45 GBP
Common Stock	Purchase	216	45.00125 GBP
Common Stock	Purchase	355	45.002 GBP
Common Stock	Purchase	1,149	45.0025 GBP
Common Stock	Purchase	9,564	45.005 GBP
Common Stock	Purchase	270	45.006 GBP
Common Stock	Purchase	936	45.0075 GBP
Common Stock	Purchase	6,477	45.01 GBP
Common Stock	Purchase	489	45.01125 GBP
Common Stock	Purchase	768	45.0125 GBP
Common Stock	Purchase	6,203	45.015 GBP
Common Stock	Purchase	290	45.016 GBP
Common Stock	Purchase	961	45.01625 GBP
Common Stock	Purchase	205	45.0175 GBP
Common Stock	Purchase	3,588	45.02 GBP
Common Stock	Purchase	1,502	45.02125 GBP
Common Stock	Purchase	2,453	45.0225 GBP
Common Stock	Purchase	12,534	45.025 GBP
Common Stock	Purchase	334	45.026 GBP
Common Stock	Purchase	275	45.02625 GBP
Common Stock	Purchase	1,473	45.0275 GBP
Common Stock	Purchase	8,014	45.03 GBP
Common Stock	Purchase	265	45.031 GBP
Common Stock	Purchase	695	45.03125 GBP
Common Stock	Purchase	1,994	45.0325 GBP
Common Stock	Purchase	225	45.03375 GBP
Common Stock	Purchase	5,739	45.035 GBP
Common Stock	Purchase	2,683	45.03625 GBP
Common Stock	Purchase	907	45.0375 GBP
Common Stock	Purchase	9,072	45.04 GBP
Common Stock	Purchase	356	45.04125 GBP
Common Stock	Purchase	2,517	45.045 GBP
Common Stock	Purchase	164	45.0475 GBP
Common Stock	Purchase	5,691	45.05 GBP
Common Stock	Purchase	587	45.051 GBP
Common Stock	Purchase	375	45.052 GBP
Common Stock	Purchase	96	45.0525 GBP
Common Stock	Purchase	4,514	45.055 GBP
Common Stock	Purchase	450	45.05625 GBP
Common Stock	Purchase	716	45.0575 GBP
Common Stock	Purchase	6,705	45.06 GBP
Common Stock	Purchase	341	45.061 GBP
Common Stock	Purchase	1,778	45.06125 GBP
Common Stock	Purchase	1,520	45.0625 GBP
Common Stock	Purchase	4,620	45.065 GBP
Common Stock	Purchase	306	45.066 GBP
Common Stock	Purchase	1,179	45.06625 GBP
Common Stock	Purchase	4,977	45.07 GBP
Common Stock	Purchase	337	45.071 GBP
Common Stock	Purchase	573	45.07125 GBP
Common Stock	Purchase	789	45.0725 GBP
Common Stock	Purchase	8,701	45.075 GBP
Common Stock	Purchase	595	45.076 GBP
Common Stock	Purchase	1,380	45.07625 GBP
Common Stock	Purchase	505	45.0775 GBP
Common Stock	Purchase	24,637	45.08 GBP
Common Stock	Purchase	323	45.081 GBP
Common Stock	Purchase	1,696	45.08125 GBP
Common Stock	Purchase	993	45.0825 GBP
Common Stock	Purchase	16,080	45.085 GBP
Common Stock	Purchase	1,370	45.086 GBP
Common Stock	Purchase	2,095	45.08625 GBP
Common Stock	Purchase	325	45.087 GBP
Common Stock	Purchase	1,351	45.0875 GBP
Common Stock	Purchase	27,966	45.09 GBP
Common Stock	Purchase	990	45.091 GBP
Common Stock	Purchase	3,371	45.09125 GBP
Common Stock	Purchase	350	45.0925 GBP
Common Stock	Purchase	17,823	45.095 GBP
Common Stock	Purchase	1,267	45.096 GBP
Common Stock	Purchase	3,194	45.09625 GBP
Common Stock	Purchase	292	45.097 GBP
Common Stock	Purchase	251	45.0975 GBP
Common Stock	Purchase	27,474	45.1 GBP
Common Stock	Purchase	607	45.101 GBP
Common Stock	Purchase	2,693	45.10125 GBP
Common Stock	Purchase	336	45.102 GBP
Common Stock	Purchase	310	45.1025 GBP
Common Stock	Purchase	28,849	45.105 GBP
Common Stock	Purchase	264	45.106 GBP
Common Stock	Purchase	3,405	45.10625 GBP
Common Stock	Purchase	661	45.1075 GBP
Common Stock	Purchase	18,093	45.11 GBP
Common Stock	Purchase	274	45.111 GBP
Common Stock	Purchase	931	45.11125 GBP
Common Stock	Purchase	815	45.1125 GBP
Common Stock	Purchase	21,685	45.115 GBP
Common Stock	Purchase	1,568	45.11625 GBP
Common Stock	Purchase	1,526	45.1175 GBP
Common Stock	Purchase	338	45.119 GBP
Common Stock	Purchase	22,786	45.12 GBP
Common Stock	Purchase	204	45.12125 GBP
Common Stock	Purchase	585	45.123 GBP
Common Stock	Purchase	4,723	45.125 GBP
Common Stock	Purchase	202	45.12625 GBP
Common Stock	Purchase	1,063	45.1275 GBP
Common Stock	Purchase	18,115	45.13 GBP
Common Stock	Purchase	449	45.13125 GBP
Common Stock	Purchase	33	45.1325 GBP
Common Stock	Purchase	7,220	45.135 GBP
Common Stock	Purchase	285	45.13625 GBP
Common Stock	Purchase	11,415	45.14 GBP
Common Stock	Purchase	2,068	45.14125 GBP
Common Stock	Purchase	18,399	45.145 GBP
Common Stock	Purchase	300	45.146 GBP
Common Stock	Purchase	848	45.14625 GBP
Common Stock	Purchase	432	45.1475 GBP
Common Stock	Purchase	21,666	45.15 GBP
Common Stock	Purchase	320	45.151 GBP
Common Stock	Purchase	4,100	45.15125 GBP
Common Stock	Purchase	224	45.152 GBP
Common Stock	Purchase	2,150	45.1525 GBP
Common Stock	Purchase	1,590	45.15375 GBP
Common Stock	Purchase	19,451	45.155 GBP
Common Stock	Purchase	553	45.156 GBP
Common Stock	Purchase	972	45.15625 GBP
Common Stock	Purchase	1,007	45.1575 GBP
Common Stock	Purchase	24,081	45.16 GBP
Common Stock	Purchase	888	45.16125 GBP
Common Stock	Purchase	3,107	45.1625 GBP
Common Stock	Purchase	32,032	45.165 GBP
Common Stock	Purchase	4,262	45.16625 GBP
Common Stock	Purchase	1,545	45.1675 GBP
Common Stock	Purchase	14,863	45.17 GBP
Common Stock	Purchase	620	45.171 GBP
Common Stock	Purchase	1,092	45.17125 GBP
Common Stock	Purchase	2,003	45.1725 GBP
Common Stock	Purchase	275	45.17375 GBP
Common Stock	Purchase	9,732	45.175 GBP
Common Stock	Purchase	805	45.17625 GBP
Common Stock	Purchase	470	45.1775 GBP
Common Stock	Purchase	257,960	45.18 GBP
Common Stock	Purchase	583	45.181 GBP
Common Stock	Purchase	692	45.1825 GBP
Common Stock	Purchase	13,400	45.185 GBP
Common Stock	Purchase	248	45.18625 GBP
Common Stock	Purchase	10,796	45.19 GBP
Common Stock	Purchase	317	45.19125 GBP
Common Stock	Purchase	288	45.1925 GBP
Common Stock	Purchase	9,022	45.195 GBP
Common Stock	Purchase	840	45.19625 GBP
Common Stock	Purchase	371	45.1975 GBP
Common Stock	Purchase	20,424	45.2 GBP
Common Stock	Purchase	1,595	45.20125 GBP
Common Stock	Purchase	15,463	45.205 GBP
Common Stock	Purchase	210	45.206 GBP
Common Stock	Purchase	1,258	45.20625 GBP
Common Stock	Purchase	151	45.2075 GBP
Common Stock	Purchase	17,257	45.21 GBP
Common Stock	Purchase	299	45.21125 GBP
Common Stock	Purchase	82	45.2125 GBP
Common Stock	Purchase	14,493	45.215 GBP
Common Stock	Purchase	2,495	45.21625 GBP
Common Stock	Purchase	962	45.2175 GBP
Common Stock	Purchase	24,640	45.22 GBP
Common Stock	Purchase	619	45.22125 GBP
Common Stock	Purchase	101	45.2225 GBP
Common Stock	Purchase	12,526	45.225 GBP
Common Stock	Purchase	1,890	45.22625 GBP
Common Stock	Purchase	607	45.2275 GBP
Common Stock	Purchase	20,735	45.23 GBP
Common Stock	Purchase	2,993	45.23125 GBP
Common Stock	Purchase	240	45.2325 GBP
Common Stock	Purchase	22,694	45.235 GBP
Common Stock	Purchase	1,748	45.23625 GBP
Common Stock	Purchase	3,052	45.2375 GBP
Common Stock	Purchase	19,004	45.24 GBP
Common Stock	Purchase	1,568	45.24125 GBP
Common Stock	Purchase	16,836	45.245 GBP
Common Stock	Purchase	892	45.24625 GBP
Common Stock	Purchase	2,986	45.2475 GBP
Common Stock	Purchase	60,393	45.25 GBP
Common Stock	Purchase	1,532	45.25125 GBP
Common Stock	Purchase	2,060	45.2525 GBP
Common Stock	Purchase	13,651	45.255 GBP
Common Stock	Purchase	623	45.2575 GBP
Common Stock	Purchase	9,339	45.26 GBP
Common Stock	Purchase	742	45.26125 GBP
Common Stock	Purchase	468	45.2625 GBP
Common Stock	Purchase	12,812	45.265 GBP
Common Stock	Purchase	823	45.26625 GBP
Common Stock	Purchase	1,130	45.2675 GBP
Common Stock	Purchase	11,350	45.27 GBP
Common Stock	Purchase	1,998	45.27125 GBP
Common Stock	Purchase	475	45.2725 GBP
Common Stock	Purchase	6,302	45.275 GBP
Common Stock	Purchase	792	45.27625 GBP
Common Stock	Purchase	13,213	45.28 GBP
Common Stock	Purchase	2,861	45.28125 GBP
Common Stock	Purchase	4,153	45.285 GBP
Common Stock	Purchase	2,019	45.28625 GBP
Common Stock	Purchase	372	45.287 GBP
Common Stock	Purchase	455	45.2875 GBP
Common Stock	Purchase	6,889	45.29 GBP
Common Stock	Purchase	307	45.291 GBP
Common Stock	Purchase	1,786	45.29125 GBP
Common Stock	Purchase	207	45.2925 GBP
Common Stock	Purchase	6,692	45.295 GBP
Common Stock	Purchase	570	45.296 GBP
Common Stock	Purchase	2,443	45.29625 GBP
Common Stock	Purchase	576	45.2975 GBP
Common Stock	Purchase	13,293	45.3 GBP
Common Stock	Purchase	1,199	45.30125 GBP
Common Stock	Purchase	10,481	45.305 GBP
Common Stock	Purchase	1,915	45.30625 GBP
Common Stock	Purchase	7,712	45.31 GBP
Common Stock	Purchase	1,719	45.31125 GBP
Common Stock	Purchase	220	45.3125 GBP
Common Stock	Purchase	3,437	45.315 GBP
Common Stock	Purchase	3,680	45.32 GBP
Common Stock	Purchase	205	45.32125 GBP
Common Stock	Purchase	4,027	45.325 GBP
Common Stock	Purchase	1,459	45.32625 GBP
Common Stock	Purchase	1,068	45.3275 GBP
Common Stock	Purchase	9,851	45.33 GBP
Common Stock	Purchase	673	45.33125 GBP
Common Stock	Purchase	312	45.332 GBP
Common Stock	Purchase	274	45.3325 GBP
Common Stock	Purchase	8,749	45.335 GBP
Common Stock	Purchase	477	45.33625 GBP
Common Stock	Purchase	257	45.3375 GBP
Common Stock	Purchase	2,583	45.34 GBP
Common Stock	Purchase	223	45.3425 GBP
Common Stock	Purchase	3,950	45.345 GBP
Common Stock	Purchase	15	45.3475 GBP
Common Stock	Purchase	7,133	45.35 GBP
Common Stock	Purchase	285	45.3525 GBP
Common Stock	Purchase	3,791	45.355 GBP
Common Stock	Purchase	4,118	45.36 GBP
Common Stock	Purchase	336	45.36125 GBP
Common Stock	Purchase	1,418	45.365 GBP
Common Stock	Purchase	367	45.36625 GBP
Common Stock	Purchase	538	45.37 GBP
Common Stock	Purchase	2,220	45.375 GBP
Common Stock	Purchase	374	45.376 GBP
Common Stock	Purchase	2,469	45.38 GBP
Common Stock	Purchase	275	45.381 GBP
Common Stock	Purchase	1,951	45.385 GBP
Common Stock	Purchase	530	45.38625 GBP
Common Stock	Purchase	233	45.3875 GBP
Common Stock	Purchase	5,769	45.39 GBP
Common Stock	Purchase	8,392	45.395 GBP
Common Stock	Purchase	784	45.39625 GBP
Common Stock	Purchase	275	45.3975 GBP
Common Stock	Purchase	14,909	45.4 GBP
Common Stock	Purchase	290	45.40125 GBP
Common Stock	Purchase	266	45.4025 GBP
Common Stock	Purchase	2,643	45.405 GBP
Common Stock	Purchase	1,580	45.41 GBP
Common Stock	Purchase	702	45.415 GBP
Common Stock	Purchase	488	45.42 GBP
Common Stock	Purchase	260	45.42125 GBP
Common Stock	Purchase	799	45.425 GBP
Common Stock	Purchase	216	45.4275 GBP
Common Stock	Purchase	610	45.43 GBP
Common Stock	Purchase	1,126	45.435 GBP
Common Stock	Purchase	3,862	45.44 GBP
Common Stock	Purchase	3,166	45.445 GBP
Common Stock	Purchase	270	45.446 GBP
Common Stock	Purchase	57	45.4475 GBP
Common Stock	Purchase	2,766	45.45 GBP
Common Stock	Purchase	270	45.451 GBP
Common Stock	Purchase	574	45.4525 GBP
Common Stock	Purchase	2,514	45.455 GBP
Common Stock	Purchase	2,107	45.46 GBP
Common Stock	Purchase	216	45.4625 GBP
Common Stock	Purchase	2,559	45.465 GBP
Common Stock	Purchase	1,449	45.47 GBP
Common Stock	Purchase	230	45.47125 GBP
Common Stock	Purchase	550	45.475 GBP
Common Stock	Purchase	413	45.47625 GBP
Common Stock	Purchase	300	45.48 GBP
Common Stock	Purchase	170	45.64 GBP
Common Stock	Purchase	130	45.665 GBP
Common Stock	Purchase	160	45.67 GBP
Common Stock	Purchase	210	45.675 GBP
Common Stock	Purchase	140	45.76 GBP
Common Stock	Purchase	920	45.765 GBP
Common Stock	Purchase	330	45.77 GBP
Common Stock	Purchase	130	45.775 GBP
Common Stock	Purchase	280	45.78 GBP
Common Stock	Purchase	320	45.785 GBP
Common Stock	Purchase	240	45.79 GBP
Common Stock	Purchase	1,090	45.795 GBP
Common Stock	Purchase	168	45.815 GBP
Common Stock	Purchase	150	45.83 GBP
Common Stock	Purchase	230	45.835 GBP
Common Stock	Purchase	150	45.84 GBP
Common Stock	Purchase	90	45.855 GBP
Common Stock	Purchase	110	45.865 GBP
Common Stock (ADR)	Purchase	100	168.87 USD
Common Stock (ADR)	Purchase	100	169.01 USD
Common Stock (ADR)	Purchase	200	169.23 USD
Common Stock (ADR)	Purchase	100	169.33 USD
Common Stock (ADR)	Purchase	200	169.5 USD
Common Stock (ADR)	Purchase	100	169.59 USD
Common Stock (ADR)	Purchase	100	169.65 USD
Common Stock (ADR)	Purchase	13	169.66 USD
Common Stock (ADR)	Purchase	100	169.68 USD
Common Stock (ADR)	Purchase	60	169.69 USD
Common Stock (ADR)	Purchase	100	169.7 USD
Common Stock (ADR)	Purchase	400	169.74 USD
Common Stock (ADR)	Purchase	100	169.76 USD
Common Stock (ADR)	Purchase	100	169.79 USD
Common Stock (ADR)	Purchase	200	169.81 USD
Common Stock (ADR)	Purchase	46	169.84 USD
Common Stock (ADR)	Purchase	541	169.87 USD
Common Stock (ADR)	Purchase	59	169.89 USD
Common Stock (ADR)	Purchase	283	169.9 USD
Common Stock (ADR)	Purchase	300	169.92 USD
Common Stock (ADR)	Purchase	300	170.02 USD
Common Stock (ADR)	Purchase	400	170.04 USD
Common Stock (ADR)	Purchase	100	170.06 USD
Common Stock (ADR)	Purchase	100	170.07 USD
Common Stock (ADR)	Purchase	100	170.11 USD
Common Stock (ADR)	Purchase	100	170.17 USD
Common Stock (ADR)	Purchase	400	170.26 USD
Common Stock (ADR)	Purchase	100	170.3 USD
Common Stock (ADR)	Purchase	110	170.32 USD
Common Stock (ADR)	Purchase	200	170.35 USD
Common Stock (ADR)	Purchase	52	170.39 USD
Common Stock (ADR)	Purchase	433	170.41 USD
Common Stock (ADR)	Purchase	123	170.42 USD
Common Stock (ADR)	Purchase	200	170.45 USD
Common Stock (ADR)	Purchase	100	170.52 USD
Common Stock (ADR)	Purchase	100	170.53 USD
Common Stock (ADR)	Purchase	300	170.59 USD
Common Stock (ADR)	Purchase	100	170.63 USD
Common Stock (ADR)	Purchase	100	170.64 USD
Common Stock (ADR)	Purchase	400	170.66 USD
Common Stock (ADR)	Purchase	400	170.67 USD
Common Stock (ADR)	Purchase	120	170.7 USD
Common Stock (ADR)	Purchase	300	170.71 USD
Common Stock (ADR)	Purchase	158	170.73 USD
Common Stock (ADR)	Purchase	300	170.75 USD
Common Stock (ADR)	Purchase	100	170.77 USD
Common Stock (ADR)	Purchase	300	170.78 USD
Common Stock (ADR)	Purchase	100	170.8 USD
Common Stock (ADR)	Purchase	100	170.83 USD
Common Stock (ADR)	Purchase	100	170.88 USD
Common Stock (ADR)	Purchase	750	170.91 USD
Common Stock (ADR)	Purchase	200	170.92 USD
Common Stock (ADR)	Purchase	700	170.93 USD
Common Stock (ADR)	Purchase	400	170.96 USD
Common Stock (ADR)	Purchase	200	170.98 USD
Common Stock (ADR)	Purchase	100	170.99 USD
Common Stock (ADR)	Purchase	1,178	171 USD
Common Stock (ADR)	Purchase	217	171.01 USD
Common Stock (ADR)	Purchase	100	171.04 USD
Common Stock (ADR)	Purchase	200	171.08 USD
Common Stock (ADR)	Purchase	700	171.1 USD
Common Stock (ADR)	Purchase	100	171.14 USD
Common Stock (ADR)	Purchase	116	171.15 USD
Common Stock (ADR)	Purchase	31	171.16 USD
Common Stock (ADR)	Purchase	125	171.18 USD
Common Stock (ADR)	Purchase	1,307	171.2 USD
Common Stock (ADR)	Purchase	2,009	171.21 USD
Common Stock (ADR)	Purchase	200	171.23 USD
Common Stock (ADR)	Purchase	600	171.24 USD
Common Stock (ADR)	Purchase	600	171.25 USD
Common Stock (ADR)	Purchase	120	171.26 USD
Common Stock (ADR)	Purchase	660	171.27 USD
Common Stock (ADR)	Purchase	325	171.28 USD
Common Stock (ADR)	Purchase	500	171.29 USD
Common Stock (ADR)	Purchase	903	171.3 USD
Common Stock (ADR)	Purchase	110	171.31 USD
Common Stock (ADR)	Purchase	200	171.32 USD
Common Stock (ADR)	Purchase	400	171.34 USD
Common Stock (ADR)	Purchase	1,246	171.35 USD
Common Stock (ADR)	Purchase	500	171.36 USD
Common Stock (ADR)	Purchase	200	171.38 USD
Common Stock (ADR)	Purchase	300	171.39 USD
Common Stock (ADR)	Purchase	490	171.4 USD
Common Stock (ADR)	Purchase	210	171.41 USD
Common Stock (ADR)	Purchase	500	171.42 USD
Common Stock (ADR)	Purchase	200	171.44 USD
Common Stock (ADR)	Purchase	110	171.45 USD
Common Stock (ADR)	Purchase	200	171.46 USD
Common Stock (ADR)	Purchase	200	171.48 USD
Common Stock (ADR)	Purchase	500	171.49 USD
Common Stock (ADR)	Purchase	1,011	171.5 USD
Common Stock (ADR)	Purchase	200	171.51 USD
Common Stock (ADR)	Purchase	200	171.52 USD
Common Stock (ADR)	Purchase	100	171.53 USD
Common Stock (ADR)	Purchase	100	171.56 USD
Common Stock (ADR)	Purchase	200	171.57 USD
Common Stock (ADR)	Purchase	100	171.575 USD
Common Stock (ADR)	Purchase	100	171.58 USD
Common Stock (ADR)	Purchase	600	171.59 USD
Common Stock (ADR)	Purchase	420	171.6 USD
Common Stock (ADR)	Purchase	100	171.605 USD
Common Stock (ADR)	Purchase	253	171.61 USD
Common Stock (ADR)	Purchase	100	171.62 USD
Common Stock (ADR)	Purchase	200	171.63 USD
Common Stock (ADR)	Purchase	600	171.64 USD
Common Stock (ADR)	Purchase	400	171.65 USD
Common Stock (ADR)	Purchase	100	171.66 USD
Common Stock (ADR)	Purchase	550	171.67 USD
Common Stock (ADR)	Purchase	116	171.73 USD
Common Stock (ADR)	Purchase	228	171.79 USD
Common Stock (ADR)	Purchase	100	171.81 USD
Common Stock (ADR)	Purchase	200	171.82 USD
Common Stock (ADR)	Purchase	200	171.84 USD
Common Stock (ADR)	Purchase	100	171.85 USD
Common Stock (ADR)	Purchase	184	171.88 USD
Common Stock (ADR)	Purchase	200	171.9 USD
Common Stock (ADR)	Purchase	100	171.92 USD
Common Stock	Sale	-522	44.61 GBP
Common Stock	Sale	-315	44.614 GBP
Common Stock	Sale	-556	44.615 GBP
Common Stock	Sale	-614	44.62 GBP
Common Stock	Sale	-3,000	44.6225 GBP
Common Stock	Sale	-2,307	44.625 GBP
Common Stock	Sale	-264	44.6275 GBP
Common Stock	Sale	-641	44.62875 GBP
Common Stock	Sale	-375	44.629 GBP
Common Stock	Sale	-1,509	44.63 GBP
Common Stock	Sale	-1,708	44.63375 GBP
Common Stock	Sale	-1,116	44.635 GBP
Common Stock	Sale	-863	44.6375 GBP
Common Stock	Sale	-213	44.63875 GBP
Common Stock	Sale	-1,094	44.64 GBP
Common Stock	Sale	-1,201	44.643 GBP
Common Stock	Sale	-1,186	44.64375 GBP
Common Stock	Sale	-5,180	44.645 GBP
Common Stock	Sale	-311	44.6475 GBP
Common Stock	Sale	-319	44.648 GBP
Common Stock	Sale	-303	44.64875 GBP
Common Stock	Sale	-2,274	44.649 GBP
Common Stock	Sale	-2,504	44.65 GBP
Common Stock	Sale	-449	44.6525 GBP
Common Stock	Sale	-375	44.653 GBP
Common Stock	Sale	-266	44.65375 GBP
Common Stock	Sale	-1,333	44.655 GBP
Common Stock	Sale	-793	44.6575 GBP
Common Stock	Sale	-1,006	44.66 GBP
Common Stock	Sale	-602	44.6625 GBP
Common Stock	Sale	-290	44.663 GBP
Common Stock	Sale	-597	44.66375 GBP
Common Stock	Sale	-5,120	44.665 GBP
Common Stock	Sale	-515	44.67 GBP
Common Stock	Sale	-300	44.6725 GBP
Common Stock	Sale	-773	44.673 GBP
Common Stock	Sale	-420	44.67375 GBP
Common Stock	Sale	-3,069	44.675 GBP
Common Stock	Sale	-484	44.67875 GBP
Common Stock	Sale	-994	44.68 GBP
Common Stock	Sale	-870	44.685 GBP
Common Stock	Sale	-321	44.689 GBP
Common Stock	Sale	-1,329	44.69 GBP
Common Stock	Sale	-632	44.69375 GBP
Common Stock	Sale	-298	44.694 GBP
Common Stock	Sale	-441	44.695 GBP
Common Stock	Sale	-302	44.69875 GBP
Common Stock	Sale	-11,657	44.7 GBP
Common Stock	Sale	-261	44.70375 GBP
Common Stock	Sale	-328	44.704 GBP
Common Stock	Sale	-616	44.705 GBP
Common Stock	Sale	-322	44.709 GBP
Common Stock	Sale	-671	44.71 GBP
Common Stock	Sale	-1,240	44.715 GBP
Common Stock	Sale	-305	44.718 GBP
Common Stock	Sale	-1,032	44.72 GBP
Common Stock	Sale	-429	44.7225 GBP
Common Stock	Sale	-961	44.725 GBP
Common Stock	Sale	-342	44.7275 GBP
Common Stock	Sale	-268	44.728 GBP
Common Stock	Sale	-2,392	44.73 GBP
Common Stock	Sale	-285	44.735 GBP
Common Stock	Sale	-1,666	44.74 GBP
Common Stock	Sale	-465	44.7425 GBP
Common Stock	Sale	-5,913	44.745 GBP
Common Stock	Sale	-1,294	44.7475 GBP
Common Stock	Sale	-3,093	44.75 GBP
Common Stock	Sale	-1,047	44.75375 GBP
Common Stock	Sale	-2,503	44.755 GBP
Common Stock	Sale	-1,483	44.7575 GBP
Common Stock	Sale	-2,322	44.76 GBP
Common Stock	Sale	-454	44.7625 GBP
Common Stock	Sale	-7,340	44.765 GBP
Common Stock	Sale	-1,099	44.7675 GBP
Common Stock	Sale	-9,328	44.77 GBP
Common Stock	Sale	-301	44.77375 GBP
Common Stock	Sale	-2,769	44.775 GBP
Common Stock	Sale	-331	44.7775 GBP
Common Stock	Sale	-6,589	44.78 GBP
Common Stock	Sale	-4,817	44.785 GBP
Common Stock	Sale	-470	44.78875 GBP
Common Stock	Sale	-10,331	44.79 GBP
Common Stock	Sale	-319	44.7925 GBP
Common Stock	Sale	-397	44.79375 GBP
Common Stock	Sale	-6,470	44.795 GBP
Common Stock	Sale	-43	44.7975 GBP
Common Stock	Sale	-126,166	44.8 GBP
Common Stock	Sale	-28	44.8025 GBP
Common Stock	Sale	-924	44.80375 GBP
Common Stock	Sale	-364	44.804 GBP
Common Stock	Sale	-12,921	44.805 GBP
Common Stock	Sale	-2,800	44.8075 GBP
Common Stock	Sale	-240	44.80875 GBP
Common Stock	Sale	-5,630	44.81 GBP
Common Stock	Sale	-493	44.8125 GBP
Common Stock	Sale	-1,031	44.81375 GBP
Common Stock	Sale	-298	44.814 GBP
Common Stock	Sale	-4,169	44.815 GBP
Common Stock	Sale	-61	44.8175 GBP
Common Stock	Sale	-584	44.81875 GBP
Common Stock	Sale	-1,230	44.82 GBP
Common Stock	Sale	-1,102	44.82375 GBP
Common Stock	Sale	-974	44.824 GBP
Common Stock	Sale	-3,634	44.825 GBP
Common Stock	Sale	-227	44.8275 GBP
Common Stock	Sale	-237	44.82875 GBP
Common Stock	Sale	-3,729	44.83 GBP
Common Stock	Sale	-2,967	44.8325 GBP
Common Stock	Sale	-432	44.83375 GBP
Common Stock	Sale	-272	44.834 GBP
Common Stock	Sale	-6,984	44.835 GBP
Common Stock	Sale	-1,237	44.8375 GBP
Common Stock	Sale	-494	44.83875 GBP
Common Stock	Sale	-1,151	44.84 GBP
Common Stock	Sale	-431	44.84125 GBP
Common Stock	Sale	-440	44.8425 GBP
Common Stock	Sale	-374	44.843 GBP
Common Stock	Sale	-245	44.84375 GBP
Common Stock	Sale	-2,098	44.845 GBP
Common Stock	Sale	-1,070	44.84875 GBP
Common Stock	Sale	-6,747	44.85 GBP
Common Stock	Sale	-575	44.85375 GBP
Common Stock	Sale	-268	44.854 GBP
Common Stock	Sale	-6,051	44.855 GBP
Common Stock	Sale	-822	44.8575 GBP
Common Stock	Sale	-1,014	44.85875 GBP
Common Stock	Sale	-2,102	44.86 GBP
Common Stock	Sale	-360	44.863 GBP
Common Stock	Sale	-529	44.86375 GBP
Common Stock	Sale	-2,994	44.865 GBP
Common Stock	Sale	-240	44.86625 GBP
Common Stock	Sale	-1,479	44.86875 GBP
Common Stock	Sale	-3,749	44.87 GBP
Common Stock	Sale	-55	44.8725 GBP
Common Stock	Sale	-3,505	44.875 GBP
Common Stock	Sale	-1,315	44.8775 GBP
Common Stock	Sale	-335	44.87875 GBP
Common Stock	Sale	-2,827	44.88 GBP
Common Stock	Sale	-1,164	44.8825 GBP
Common Stock	Sale	-1,546	44.88375 GBP
Common Stock	Sale	-670	44.884 GBP
Common Stock	Sale	-4,469	44.885 GBP
Common Stock	Sale	-1,491	44.8875 GBP
Common Stock	Sale	-2,177	44.88875 GBP
Common Stock	Sale	-3,969	44.89 GBP
Common Stock	Sale	-1,912	44.8925 GBP
Common Stock	Sale	-642	44.89375 GBP
Common Stock	Sale	-1,430	44.895 GBP
Common Stock	Sale	-329	44.8975 GBP
Common Stock	Sale	-590	44.89875 GBP
Common Stock	Sale	-6,430	44.9 GBP
Common Stock	Sale	-704	44.9025 GBP
Common Stock	Sale	-3,000	44.90375 GBP
Common Stock	Sale	-322	44.904 GBP
Common Stock	Sale	-3,532	44.905 GBP
Common Stock	Sale	-646	44.9075 GBP
Common Stock	Sale	-534	44.90875 GBP
Common Stock	Sale	-8,569	44.91 GBP
Common Stock	Sale	-537	44.91375 GBP
Common Stock	Sale	-1,459	44.915 GBP
Common Stock	Sale	-3,178	44.92 GBP
Common Stock	Sale	-269	44.924 GBP
Common Stock	Sale	-3,363	44.925 GBP
Common Stock	Sale	-5,057	44.93 GBP
Common Stock	Sale	-5,568	44.935 GBP
Common Stock	Sale	-1,941	44.94 GBP
Common Stock	Sale	-120	44.945 GBP
Common Stock	Sale	-5,363	44.95 GBP
Common Stock	Sale	-4,295	44.955 GBP
Common Stock	Sale	-3,098	44.96 GBP
Common Stock	Sale	-6,586	44.965 GBP
Common Stock	Sale	-3,615	44.97 GBP
Common Stock	Sale	-4,039	44.975 GBP
Common Stock	Sale	-50	44.9775 GBP
Common Stock	Sale	-1,871	44.97875 GBP
Common Stock	Sale	-2,138	44.98 GBP
Common Stock	Sale	-115	44.9825 GBP
Common Stock	Sale	-4,270	44.985 GBP
Common Stock	Sale	-383	44.98875 GBP
Common Stock	Sale	-3,625	44.99 GBP
Common Stock	Sale	-18,669	44.995 GBP
Common Stock	Sale	-295	44.9975 GBP
Common Stock	Sale	-36,780	45 GBP
Common Stock	Sale	-559	45.0025 GBP
Common Stock	Sale	-8,433	45.005 GBP
Common Stock	Sale	-1,000	45.00875 GBP
Common Stock	Sale	-4,282	45.01 GBP
Common Stock	Sale	-317	45.0125 GBP
Common Stock	Sale	-4,952	45.015 GBP
Common Stock	Sale	-45	45.0175 GBP
Common Stock	Sale	-9,825	45.02 GBP
Common Stock	Sale	-3,211	45.025 GBP
Common Stock	Sale	-632	45.029 GBP
Common Stock	Sale	-3,861	45.03 GBP
Common Stock	Sale	-351	45.033 GBP
Common Stock	Sale	-202	45.03375 GBP
Common Stock	Sale	-824	45.034 GBP
Common Stock	Sale	-12,688	45.035 GBP
Common Stock	Sale	-687	45.0375 GBP
Common Stock	Sale	-288	45.039 GBP
Common Stock	Sale	-15,670	45.04 GBP
Common Stock	Sale	-5,577	45.045 GBP
Common Stock	Sale	-2,000	45.04875 GBP
Common Stock	Sale	-5,317	45.05 GBP
Common Stock	Sale	-995	45.0525 GBP
Common Stock	Sale	-3,858	45.055 GBP
Common Stock	Sale	-1,131	45.05875 GBP
Common Stock	Sale	-2,626	45.06 GBP
Common Stock	Sale	-209	45.06375 GBP
Common Stock	Sale	-965	45.064 GBP
Common Stock	Sale	-7,638	45.065 GBP
Common Stock	Sale	-885	45.0675 GBP
Common Stock	Sale	-776	45.06875 GBP
Common Stock	Sale	-7,922	45.07 GBP
Common Stock	Sale	-469	45.07375 GBP
Common Stock	Sale	-10,318	45.075 GBP
Common Stock	Sale	-1,242	45.0775 GBP
Common Stock	Sale	-2,083	45.07875 GBP
Common Stock	Sale	-16,915	45.08 GBP
Common Stock	Sale	-1,363	45.0825 GBP
Common Stock	Sale	-1,477	45.08375 GBP
Common Stock	Sale	-262	45.084 GBP
Common Stock	Sale	-17,670	45.085 GBP
Common Stock	Sale	-2,427	45.0875 GBP
Common Stock	Sale	-2,090	45.08875 GBP
Common Stock	Sale	-24,490	45.09 GBP
Common Stock	Sale	-403	45.09125 GBP
Common Stock	Sale	-3,117	45.0925 GBP
Common Stock	Sale	-317	45.093 GBP
Common Stock	Sale	-2,112	45.09375 GBP
Common Stock	Sale	-1,806	45.094 GBP
Common Stock	Sale	-15,469	45.095 GBP
Common Stock	Sale	-1,538	45.0975 GBP
Common Stock	Sale	-696	45.098 GBP
Common Stock	Sale	-1,636	45.09875 GBP
Common Stock	Sale	-2,229	45.099 GBP
Common Stock	Sale	-28,475	45.1 GBP
Common Stock	Sale	-1,094	45.1025 GBP
Common Stock	Sale	-280	45.103 GBP
Common Stock	Sale	-970	45.10375 GBP
Common Stock	Sale	-5,817	45.104 GBP
Common Stock	Sale	-16,841	45.105 GBP
Common Stock	Sale	-227	45.1075 GBP
Common Stock	Sale	-362	45.108 GBP
Common Stock	Sale	-1,288	45.10875 GBP
Common Stock	Sale	-1,621	45.109 GBP
Common Stock	Sale	-11,478	45.11 GBP
Common Stock	Sale	-283	45.112 GBP
Common Stock	Sale	-511	45.1125 GBP
Common Stock	Sale	-703	45.11375 GBP
Common Stock	Sale	-303	45.114 GBP
Common Stock	Sale	-13,246	45.115 GBP
Common Stock	Sale	-69	45.1175 GBP
Common Stock	Sale	-290	45.118 GBP
Common Stock	Sale	-1,221	45.11875 GBP
Common Stock	Sale	-282	45.119 GBP
Common Stock	Sale	-11,374	45.12 GBP
Common Stock	Sale	-141	45.1225 GBP
Common Stock	Sale	-351	45.123 GBP
Common Stock	Sale	-6,518	45.125 GBP
Common Stock	Sale	-1,930	45.1275 GBP
Common Stock	Sale	-351	45.128 GBP
Common Stock	Sale	-469	45.12875 GBP
Common Stock	Sale	-635	45.129 GBP
Common Stock	Sale	-4,852	45.13 GBP
Common Stock	Sale	-939	45.13125 GBP
Common Stock	Sale	-920	45.1325 GBP
Common Stock	Sale	-294	45.133 GBP
Common Stock	Sale	-207	45.13375 GBP
Common Stock	Sale	-9,694	45.135 GBP
Common Stock	Sale	-1,353	45.13625 GBP
Common Stock	Sale	-9,006	45.14 GBP
Common Stock	Sale	-160	45.1425 GBP
Common Stock	Sale	-745	45.14375 GBP
Common Stock	Sale	-15,056	45.145 GBP
Common Stock	Sale	-910	45.1475 GBP
Common Stock	Sale	-945	45.14875 GBP
Common Stock	Sale	-2,250	45.149 GBP
Common Stock	Sale	-98,925	45.15 GBP
Common Stock	Sale	-1,487	45.1525 GBP
Common Stock	Sale	-594	45.15375 GBP
Common Stock	Sale	-29,004	45.155 GBP
Common Stock	Sale	-1,685	45.1575 GBP
Common Stock	Sale	-498	45.15875 GBP
Common Stock	Sale	-2,609	45.159 GBP
Common Stock	Sale	-23,435	45.16 GBP
Common Stock	Sale	-668	45.16375 GBP
Common Stock	Sale	-541	45.164 GBP
Common Stock	Sale	-21,641	45.165 GBP
Common Stock	Sale	-75	45.1675 GBP
Common Stock	Sale	-1,137	45.16875 GBP
Common Stock	Sale	-3,095	45.169 GBP
Common Stock	Sale	-14,637	45.17 GBP
Common Stock	Sale	-57	45.1725 GBP
Common Stock	Sale	-20,611	45.175 GBP
Common Stock	Sale	-98	45.1775 GBP
Common Stock	Sale	-304	45.17875 GBP
Common Stock	Sale	-318	45.179 GBP
Common Stock	Sale	-14,869	45.18 GBP
Common Stock	Sale	-511	45.1825 GBP
Common Stock	Sale	-543	45.18375 GBP
Common Stock	Sale	-1,476	45.184 GBP
Common Stock	Sale	-12,647	45.185 GBP
Common Stock	Sale	-321	45.189 GBP
Common Stock	Sale	-16,312	45.19 GBP
Common Stock	Sale	-1,352	45.1925 GBP
Common Stock	Sale	-16,751	45.195 GBP
Common Stock	Sale	-995	45.1975 GBP
Common Stock	Sale	-272	45.199 GBP
Common Stock	Sale	-19,217	45.2 GBP
Common Stock	Sale	-443	45.2025 GBP
Common Stock	Sale	-203	45.20375 GBP
Common Stock	Sale	-18,077	45.205 GBP
Common Stock	Sale	-902	45.2075 GBP
Common Stock	Sale	-1,427	45.20875 GBP
Common Stock	Sale	-1,913	45.209 GBP
Common Stock	Sale	-46,108	45.21 GBP
Common Stock	Sale	-137	45.2125 GBP
Common Stock	Sale	-1,505	45.214 GBP
Common Stock	Sale	-12,587	45.215 GBP
Common Stock	Sale	-435	45.216 GBP
Common Stock	Sale	-251	45.2175 GBP
Common Stock	Sale	-2,153	45.218 GBP
Common Stock	Sale	-1,360	45.21875 GBP
Common Stock	Sale	-2,313	45.219 GBP
Common Stock	Sale	-14,953	45.22 GBP
Common Stock	Sale	-569	45.2225 GBP
Common Stock	Sale	-1,223	45.224 GBP
Common Stock	Sale	-8,790	45.225 GBP
Common Stock	Sale	-1,352	45.2275 GBP
Common Stock	Sale	-324	45.228 GBP
Common Stock	Sale	-265	45.22875 GBP
Common Stock	Sale	-1,738	45.229 GBP
Common Stock	Sale	-7,938	45.23 GBP
Common Stock	Sale	-3,222	45.231 GBP
Common Stock	Sale	-791	45.2325 GBP
Common Stock	Sale	-658	45.23375 GBP
Common Stock	Sale	-666	45.234 GBP
Common Stock	Sale	-13,858	45.235 GBP
Common Stock	Sale	-592	45.237 GBP
Common Stock	Sale	-680	45.2375 GBP
Common Stock	Sale	-16,684	45.24 GBP
Common Stock	Sale	-591	45.2425 GBP
Common Stock	Sale	-1,091	45.24375 GBP
Common Stock	Sale	-308	45.244 GBP
Common Stock	Sale	-22,139	45.245 GBP
Common Stock	Sale	-2,032	45.2475 GBP
Common Stock	Sale	-16,366	45.25 GBP
Common Stock	Sale	-279	45.2525 GBP
Common Stock	Sale	-333	45.25375 GBP
Common Stock	Sale	-5,238	45.255 GBP
Common Stock	Sale	-1,056	45.2575 GBP
Common Stock	Sale	-775	45.25875 GBP
Common Stock	Sale	-4,796	45.26 GBP
Common Stock	Sale	-653	45.26375 GBP
Common Stock	Sale	-896	45.264 GBP
Common Stock	Sale	-5,710	45.265 GBP
Common Stock	Sale	-301	45.268 GBP
Common Stock	Sale	-4,727	45.27 GBP
Common Stock	Sale	-2,042	45.2725 GBP
Common Stock	Sale	-327	45.27375 GBP
Common Stock	Sale	-547	45.274 GBP
Common Stock	Sale	-3,053	45.275 GBP
Common Stock	Sale	-3,047	45.27875 GBP
Common Stock	Sale	-2,048	45.279 GBP
Common Stock	Sale	-5,723	45.28 GBP
Common Stock	Sale	-595	45.2825 GBP
Common Stock	Sale	-6,779	45.285 GBP
Common Stock	Sale	-270	45.288 GBP
Common Stock	Sale	-276	45.28875 GBP
Common Stock	Sale	-4,653	45.289 GBP
Common Stock	Sale	-12,567	45.29 GBP
Common Stock	Sale	-637	45.293 GBP
Common Stock	Sale	-891	45.29375 GBP
Common Stock	Sale	-879	45.294 GBP
Common Stock	Sale	-25,426	45.295 GBP
Common Stock	Sale	-239	45.298 GBP
Common Stock	Sale	-680	45.29875 GBP
Common Stock	Sale	-970	45.299 GBP
Common Stock	Sale	-19,868	45.3 GBP
Common Stock	Sale	-272	45.30375 GBP
Common Stock	Sale	-271	45.304 GBP
Common Stock	Sale	-6,702	45.305 GBP
Common Stock	Sale	-15	45.3075 GBP
Common Stock	Sale	-274	45.30875 GBP
Common Stock	Sale	-7,114	45.31 GBP
Common Stock	Sale	-816	45.3125 GBP
Common Stock	Sale	-3,775	45.314 GBP
Common Stock	Sale	-6,213	45.315 GBP
Common Stock	Sale	-2,948	45.31875 GBP
Common Stock	Sale	-316	45.319 GBP
Common Stock	Sale	-7,012	45.32 GBP
Common Stock	Sale	-221	45.32375 GBP
Common Stock	Sale	-6,643	45.325 GBP
Common Stock	Sale	-8,108	45.33 GBP
Common Stock	Sale	-932	45.33375 GBP
Common Stock	Sale	-268	45.334 GBP
Common Stock	Sale	-16,522	45.335 GBP
Common Stock	Sale	-9,744	45.34 GBP
Common Stock	Sale	-3,200	45.345 GBP
Common Stock	Sale	-1,180	45.35 GBP
Common Stock	Sale	-5,191	45.355 GBP
Common Stock	Sale	-747	45.36 GBP
Common Stock	Sale	-367	45.364 GBP
Common Stock	Sale	-1,358	45.365 GBP
Common Stock	Sale	-588	45.37 GBP
Common Stock	Sale	-1,300	45.375 GBP
Common Stock	Sale	-1,478	45.38 GBP
Common Stock	Sale	-1,597	45.385 GBP
Common Stock	Sale	-480	45.3875 GBP
Common Stock	Sale	-268	45.38875 GBP
Common Stock	Sale	-3,603	45.39 GBP
Common Stock	Sale	-660	45.394 GBP
Common Stock	Sale	-2,855	45.395 GBP
Common Stock	Sale	-3,944	45.4 GBP
Common Stock	Sale	-189	45.4025 GBP
Common Stock	Sale	-2,029	45.405 GBP
Common Stock	Sale	-303	45.4075 GBP
Common Stock	Sale	-814	45.41 GBP
Common Stock	Sale	-216	45.4125 GBP
Common Stock	Sale	-770	45.415 GBP
Common Stock	Sale	-2,095	45.42 GBP
Common Stock	Sale	-2,133	45.425 GBP
Common Stock	Sale	-237	45.42875 GBP
Common Stock	Sale	-2,517	45.43 GBP
Common Stock	Sale	-2,841	45.435 GBP
Common Stock	Sale	-1,818	45.44 GBP
Common Stock	Sale	-222	45.44375 GBP
Common Stock	Sale	-2,532	45.445 GBP
Common Stock	Sale	-2,044	45.45 GBP
Common Stock	Sale	-2,170	45.455 GBP
Common Stock	Sale	-1,296	45.46 GBP
Common Stock	Sale	-143	45.465 GBP
Common Stock	Sale	-1,850	45.47 GBP
Common Stock	Sale	-278	45.475 GBP
Common Stock	Sale	-115	45.48 GBP
Common Stock	Sale	-370	45.775 GBP
Common Stock	Sale	-700	45.785 GBP
Common Stock	Sale	-602	45.79 GBP
Common Stock	Sale	-720	45.795 GBP
Common Stock	Sale	-695	45.8 GBP
Common Stock	Sale	-250	45.805 GBP
Common Stock	Sale	-530	45.815 GBP
Common Stock	Sale	-690	45.825 GBP
Common Stock	Sale	-470	45.83 GBP
Common Stock	Sale	-190	45.84 GBP
Common Stock	Sale	-530	45.845 GBP
Common Stock	Sale	-870	45.85 GBP
Common Stock	Sale	-1,035	45.855 GBP
Common Stock	Sale	-2,793	45.86 GBP
Common Stock	Sale	-130	45.865 GBP
Common Stock	Sale	-130	45.87 GBP
Common Stock	Sale	-100	45.875 GBP
Common Stock (ADR)	Sale	-100	169.27 USD
Common Stock (ADR)	Sale	-200	169.34 USD
Common Stock (ADR)	Sale	-100	169.5 USD
Common Stock (ADR)	Sale	-100	169.62 USD
Common Stock (ADR)	Sale	-100	169.64 USD
Common Stock (ADR)	Sale	-90	169.67 USD
Common Stock (ADR)	Sale	-100	169.72 USD
Common Stock (ADR)	Sale	-100	169.81 USD
Common Stock (ADR)	Sale	-211	169.82 USD
Common Stock (ADR)	Sale	-20	169.86 USD
Common Stock (ADR)	Sale	-210	169.87 USD
Common Stock (ADR)	Sale	-70	169.94 USD
Common Stock (ADR)	Sale	-100	169.96 USD
Common Stock (ADR)	Sale	-200	169.97 USD
Common Stock (ADR)	Sale	-100	170.03 USD
Common Stock (ADR)	Sale	-300	170.04 USD
Common Stock (ADR)	Sale	-100	170.11 USD
Common Stock (ADR)	Sale	-100	170.16 USD
Common Stock (ADR)	Sale	-518	170.17 USD
Common Stock (ADR)	Sale	-300	170.24 USD
Common Stock (ADR)	Sale	-269	170.26 USD
Common Stock (ADR)	Sale	-200	170.28 USD
Common Stock (ADR)	Sale	-320	170.4 USD
Common Stock (ADR)	Sale	-122	170.41 USD
Common Stock (ADR)	Sale	-7	170.47 USD
Common Stock (ADR)	Sale	-100	170.54 USD
Common Stock (ADR)	Sale	-191	170.56 USD
Common Stock (ADR)	Sale	-91	170.58 USD
Common Stock (ADR)	Sale	-200	170.59 USD
Common Stock (ADR)	Sale	-722	170.6 USD
Common Stock (ADR)	Sale	-78	170.61 USD
Common Stock (ADR)	Sale	-200	170.62 USD
Common Stock (ADR)	Sale	-200	170.64 USD
Common Stock (ADR)	Sale	-500	170.65 USD
Common Stock (ADR)	Sale	-138	170.66 USD
Common Stock (ADR)	Sale	-266	170.67 USD
Common Stock (ADR)	Sale	-100	170.7 USD
Common Stock (ADR)	Sale	-76	170.74 USD
Common Stock (ADR)	Sale	-600	170.75 USD
Common Stock (ADR)	Sale	-100	170.77 USD
Common Stock (ADR)	Sale	-200	170.78 USD
Common Stock (ADR)	Sale	-200	170.8 USD
Common Stock (ADR)	Sale	-100	170.82 USD
Common Stock (ADR)	Sale	-100	170.83 USD
Common Stock (ADR)	Sale	-228	170.84 USD
Common Stock (ADR)	Sale	-200	170.86 USD
Common Stock (ADR)	Sale	-132	170.88 USD
Common Stock (ADR)	Sale	-600	170.89 USD
Common Stock (ADR)	Sale	-2,640	170.9 USD
Common Stock (ADR)	Sale	-200	170.91 USD
Common Stock (ADR)	Sale	-100	170.93 USD
Common Stock (ADR)	Sale	-250	170.94 USD
Common Stock (ADR)	Sale	-400	170.96 USD
Common Stock (ADR)	Sale	-500	170.98 USD
Common Stock (ADR)	Sale	-1,400	171 USD
Common Stock (ADR)	Sale	-25	171.01 USD
Common Stock (ADR)	Sale	-100	171.06 USD
Common Stock (ADR)	Sale	-20	171.1 USD
Common Stock (ADR)	Sale	-200	171.12 USD
Common Stock (ADR)	Sale	-487	171.13 USD
Common Stock (ADR)	Sale	-10	171.15 USD
Common Stock (ADR)	Sale	-200	171.16 USD
Common Stock (ADR)	Sale	-400	171.17 USD
Common Stock (ADR)	Sale	-400	171.18 USD
Common Stock (ADR)	Sale	-550	171.19 USD
Common Stock (ADR)	Sale	-100	171.195 USD
Common Stock (ADR)	Sale	-1,400	171.2 USD
Common Stock (ADR)	Sale	-1,010	171.21 USD
Common Stock (ADR)	Sale	-460	171.22 USD
Common Stock (ADR)	Sale	-510	171.23 USD
Common Stock (ADR)	Sale	-1,200	171.24 USD
Common Stock (ADR)	Sale	-1,090	171.25 USD
Common Stock (ADR)	Sale	-100	171.26 USD
Common Stock (ADR)	Sale	-350	171.27 USD
Common Stock (ADR)	Sale	-400	171.28 USD
Common Stock (ADR)	Sale	-200	171.3 USD
Common Stock (ADR)	Sale	-570	171.31 USD
Common Stock (ADR)	Sale	-340	171.32 USD
Common Stock (ADR)	Sale	-300	171.33 USD
Common Stock (ADR)	Sale	-500	171.34 USD
Common Stock (ADR)	Sale	-400	171.35 USD
Common Stock (ADR)	Sale	-209	171.36 USD
Common Stock (ADR)	Sale	-596	171.37 USD
Common Stock (ADR)	Sale	-268	171.38 USD
Common Stock (ADR)	Sale	-100	171.4 USD
Common Stock (ADR)	Sale	-100	171.42 USD
Common Stock (ADR)	Sale	-300	171.43 USD
Common Stock (ADR)	Sale	-114	171.44 USD
Common Stock (ADR)	Sale	-300	171.45 USD
Common Stock (ADR)	Sale	-100	171.46 USD
Common Stock (ADR)	Sale	-200	171.47 USD
Common Stock (ADR)	Sale	-200	171.48 USD
Common Stock (ADR)	Sale	-420	171.49 USD
Common Stock (ADR)	Sale	-80	171.5 USD
Common Stock (ADR)	Sale	-300	171.52 USD
Common Stock (ADR)	Sale	-406	171.54 USD
Common Stock (ADR)	Sale	-5	171.55 USD
Common Stock (ADR)	Sale	-350	171.58 USD
Common Stock (ADR)	Sale	-200	171.65 USD
Common Stock (ADR)	Sale	-100	171.74 USD
Common Stock (ADR)	Sale	-20	171.75 USD
Common Stock (ADR)	Sale	-100	171.78 USD
Common Stock (ADR)	Sale	-100	171.81 USD
Common Stock (ADR)	Sale	-200	171.86 USD
Common Stock (ADR)	Sale	-200	171.89 USD
Common Stock (ADR)	Sale	-400	171.91 USD
Common Stock (ADR)	Sale	-100	171.94 USD
Common Stock (ADR)	Sale	-100	171.95 USD
Common Stock (ADR)	Sale	-100	171.96 USD
Common Stock (ADR)	Sale	-1,016	172 USD

(b) Cash-settled derivative transactions

Class of relevant security ISIN JE00B2QKY057	Product description e.g. CFD	Nature of dealing e.g. opening/closing a long/short position, increasing/reducing a long/short position	Number of reference securities	Price per unit
Common Stock	CFD	Increasing short position	-1	45.1025 GBP
Common Stock	CFD	Reducing long position	-1,899	45.111892 GBP
Common Stock	CFD	Reducing long position	-707	45.111892 GBP
Common Stock	CFD	Reducing long position	-370	45.111892 GBP
Common Stock	CFD	Reducing long position	-79	45.111892 GBP
Common Stock	CFD	Reducing long position	-57,671	45.18 GBP
Common Stock	CFD	Reducing long position	-49,883	45.18 GBP
Common Stock	CFD	Reducing long position	-41,823	45.18 GBP
Common Stock	CFD	Reducing long position	-31,980	45.18 GBP
Common Stock	CFD	Reducing long position	-13,255	45.18 GBP
Common Stock	CFD	Reducing long position	-11,632	45.18 GBP
Common Stock	CFD	Reducing long position	-10,906	45.18 GBP
Common Stock	CFD	Reducing long position	-9,049	45.18 GBP
Common Stock	CFD	Reducing long position	-8,737	45.18 GBP
Common Stock	CFD	Reducing long position	-4,081	45.18 GBP
Common Stock	CFD	Reducing long position	-3,212	45.18 GBP
Common Stock	CFD	Reducing long position	-3,211	45.18 GBP
Common Stock	CFD	Reducing long position	-2,096	45.18 GBP
Common Stock	CFD	Reducing long position	-2,000	45.18 GBP
Common Stock	CFD	Reducing long position	-234	45.18 GBP
Common Stock	CFD	Reducing long position	-230	45.18 GBP
Common Stock	CFD	Reducing short position	1	45.105 GBP

(i) Writing, selling, purchasing or varying

Class of relevant security

ISIN

JE00B2QKY057

Product description e.g. call option

Writing, purchasing, selling, varying etc.

Number of securities to which option relates

Exercise price per unit

Type

e.g. American, European etc.

Expiry date

Option money paid/ received per unit

Common

Put Option

Writing

-3

38 GBP

American

15/03/2019

0.73 GBP

Common

Put Option

Writing

-8

46 GBP

American

21/12/2018

0.85 GBP

(ii) Exercise

Class of relevant security ISIN JE00B2QKY057	Product description e.g. call option	Exercising/ exercised against	Number of securities	Exercise price per unit
Common	Call Option	Exercise	-4	40 GBP
Common	Put Option	Exercise	-7	46 GBP
Common	Put Option	Exercise	-5	48 GBP

(d) Other dealings (including subscribing for new securities)

Class of relevant security

Nature of dealing

e.g. subscription, conversion

Details

Price per unit (if applicable)

4. OTHER INFORMATION

(a) Indemnity and other dealing arrangements

Details of any indemnity or option arrangement, or any agreement or understanding, formal or informal, relating to relevant securities which may be an inducement to deal or refrain from dealing entered into by the person making the disclosure and any party to the offer or any person acting in concert with a party to the offer:

Irrevocable commitments and letters of intent should not be included. If there are no such agreements, arrangements or understandings, state "none"

None

(b) Agreements, arrangements or understandings relating to options or derivatives

Details of any agreement, arrangement or understanding, formal or informal, between the person making the disclosure and any other person relating to:

(i) the voting rights of any relevant securities under any option; or

(ii) the voting rights or future acquisition or disposal of any relevant securities to which any derivative is referenced:

If there are no such agreements, arrangements or understandings, state "none"

None

Is a Supplemental Form 8 (Open Positions) attached?

YES

Date of disclosure:	24 December, 2018
Contact name:	Natasha Newbold
Telephone number*:	020 7645 9700

Public disclosures under Rule 8 of the Code must be made to a Regulatory Information Service.

The Panel's Market Surveillance Unit is available for consultation in relation to the Code's disclosure requirements on +44 (0)20 7638 0129.

*If the discloser is a natural person, a telephone number does not need to be included, provided contact information has been provided to the Panel's Market Surveillance Unit.

The Code can be viewed on the Panel's website at www.thetakeoverpanel.org.uk.

SUPPLEMENTAL FORM 8 (OPEN POSITIONS)

DETAILS OF OPEN STOCK-SETTLED DERIVATIVE (INCLUDING OPTION) POSITIONS, AGREEMENTS TO PURCHASE OR SELL ETC.

Note 5(i) on Rule 8 of the Takeover Code (the "Code")

1. KEY INFORMATION

Full name of person making disclosure:	Citadel Group
Name of offeror/offeree in relation to whose relevant securities the disclosure relates:	SHIRE PLC

2. STOCK-SETTLED DERIVATIVES (INCLUDING OPTIONS)

Class of relevant security ISINJE00B2QKY057	Product description e.g. call option	Written or purchased	Number of securities to which option or derivative relates	Exercise price per unit	Type e.g. American, European etc.	Expiry date
Common	Put Option	Written	5000	38 USD	American	21/06/2019
Common	Put Option	Written	12000	42 USD	American	15/03/2019
Common	Call Option	Written	-5000	44 USD	American	15/03/2019
Common	Put Option	Written	3000	38 USD	American	15/03/2019
Common	Put Option	Purchased	-1000	24 USD	American	15/03/2019
Common	Put Option	Purchased	-2000	36 USD	American	15/03/2019
Common	Call Option	Purchased	200000	170 USD	American	18/01/2019
Common	Put Option	Purchased	-1000	32 USD	American	15/03/2019
Common	Call Option	Written	-22000	48 USD	American	15/03/2019
Common	Put Option	Written	6000	40 USD	American	15/03/2019
Common	Call Option	Written	-6000	40 USD	American	15/03/2019

3. AGREEMENTS TO PURCHASE OR SELL ETC.

Full details should be given so that the nature of the interest or position can be fully understood:

It is not necessary to provide details on a Supplemental Form (Open Positions) with regard to cash-settled derivatives.

The currency of all prices and other monetary amounts should be stated.

The Panel's Market Surveillance Unit is available for consultation in relation to the Code's disclosure requirements on +44 (0)20 7638 0129.

The Code can be viewed on the Panel's website at www.thetakeoverpanel.org.uk.

This information is provided by RNS, the news service of the London Stock Exchange. RNS is approved by the Financial Conduct Authority to act as a Primary Information Provider in the United Kingdom. Terms and conditions relating to the use and distribution of this information may apply. For further information, please contact rns@lseg.com or visit www.rns.com.

END

RETFESFELFASEIE

Date		Source	Headline
8th Jan 2019	5:30 pm	GNW	Director/PDMR Shareholding
8th Jan 2019	3:20 pm	RNS	Form 8.3 - Shire plc
8th Jan 2019	3:19 pm	RNS	Form 8.3 - Takeda Pharmaceutical Company Limited
8th Jan 2019	3:13 pm	RNS	Form 8.3 - Shire plc
8th Jan 2019	3:07 pm	RNS	Form 8.5 (EPT/NON-RI)
8th Jan 2019	2:28 pm	RNS	Form 8.5 (EPT/RI) - Replacement of Shire
8th Jan 2019	2:23 pm	RNS	Form 8.5 (EPT/RI) - Replacement of Shire
8th Jan 2019	2:21 pm	RNS	Form 8.5 (EPT/RI) - Replacement of Shire
8th Jan 2019	1:57 pm	RNS	Form 8.3 - Takeda Pharmaceutical Company Limited
8th Jan 2019	1:27 pm	RNS	Form 8.3 - Shire plc
8th Jan 2019	12:31 pm	RNS	Form 8.3 - Takeda Pharmaceutical Company Limited
8th Jan 2019	12:29 pm	RNS	Form 8.3 - Takeda Pharmaceutical
8th Jan 2019	12:27 pm	RNS	Form 8.3 - Shire plc
8th Jan 2019	11:42 am	RNS	Form 8.5 (EPT/NON-RI)
8th Jan 2019	11:33 am	RNS	Form 8.5 (EPT/NON-RI)- Shire Plc
8th Jan 2019	10:49 am	RNS	Form 8.5 (EPT/RI)
8th Jan 2019	10:41 am	RNS	Form 8.3 - Takeda Pharmaceutical Company Limited
8th Jan 2019	10:26 am	RNS	Form 8.5 (EPT/RI)- Shire plc
8th Jan 2019	9:51 am	RNS	Form 8.3 - Shire Plc
8th Jan 2019	8:44 am	RNS	Form 8.5 (EPT/RI) - SHIRE PLC
8th Jan 2019	7:00 am	RNS	Form 8.3 - Takeda Pharmaceutical Company Limited
8th Jan 2019	7:00 am	GNW	Scheme becomes effective
7th Jan 2019	5:00 pm	GNW	Holding(s) in Company
7th Jan 2019	3:42 pm	RNS	Form 8.5 (EPT/RI) - Amendment
7th Jan 2019	3:20 pm	RNS	Form 8.3 - Shire plc
7th Jan 2019	3:02 pm	RNS	Form 8.3 - Shire plc
7th Jan 2019	3:00 pm	RNS	Form 8.5 (EPT/NON-RI)
7th Jan 2019	3:00 pm	RNS	Form 8.3 - Shire plc
7th Jan 2019	2:59 pm	RNS	Form 8.3 - Takeda Pharmaceutical
7th Jan 2019	2:50 pm	PRN	Form 8.3 - Shire Plc
7th Jan 2019	2:49 pm	RNS	Form 8.3 - Shire plc
7th Jan 2019	2:47 pm	RNS	Form 8.3 - Takeda Pharmaceutical Company Limited
7th Jan 2019	2:45 pm	BUS	Form 8.3 - Shire plc
7th Jan 2019	1:55 pm	RNS	Form 8.3 - Takeda Pharmaceutical Company Limited
7th Jan 2019	1:54 pm	RNS	Form 8.3 - Shire plc
7th Jan 2019	1:39 pm	RNS	Form 8.3 - [Shire Plc]
7th Jan 2019	1:32 pm	RNS	Form 8.5 (EPT/RI) - Replacement of Shire
7th Jan 2019	1:29 pm	RNS	Form 8.5 (EPT/RI) - Replacement of Shire
7th Jan 2019	12:57 pm	RNS	Form 8.3 - Takeda Pharmaceutical Company Limited
7th Jan 2019	12:56 pm	RNS	Form 8.3 - Shire plc
7th Jan 2019	12:42 pm	RNS	Form 8.5 (EPT/NON-RI)
7th Jan 2019	11:52 am	RNS	Form 8.3 - Takeda Pharmaceutical Company Limited
7th Jan 2019	11:43 am	BUS	Form 8.3 - SHIRE PLC
7th Jan 2019	11:30 am	RNS	Form 8.3 - Takeda Pharmaceutical Company Limited
7th Jan 2019	11:27 am	RNS	Form 8.3 - Shire plc
7th Jan 2019	11:01 am	RNS	Form 8.5 (EPT/RI)- Shire plc
7th Jan 2019	10:59 am	RNS	Form 8.5 (EPT/NON-RI)- Shire Plc
7th Jan 2019	10:35 am	RNS	Form 8.5 - Shire plc
7th Jan 2019	10:16 am	RNS	Form 8.5 (EPT/RI) - SHIRE PLC
7th Jan 2019	10:13 am	RNS	Form 8.5 (EPT/RI) - Amendment

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