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Pin to quick picksSareum Regulatory News (SAR)

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Edison Investment Research Limited: Sareum Holdings (SAR): Treading the TYK2 trail

5 May 2021 13:15

Edison Investment Research Limited Edison Investment Research Limited: Sareum Holdings (SAR): Treading the TYK2 trail 05-May-2021 / 13:15 GMT/BST


 

London, UK, 5 May 2021

 

Sareum Holdings (SAR): Treading the TYK2 trail

Kinase inhibitor specialist Sareum develops small molecule therapeutics with application in oncology and autoimmune disease areas. Lead asset SDC-1801 targets the autoimmune space and is nearing an inflection point, with a planned clinical trial application (CTA) filing in mid-2021 and clinical progression in Q421. The other candidate, SDC-1802, is focused on cancer and holds first-in-class promise with value to be unlocked with clinical validation. The out-licensed assets, SRA737 and FLT3+Aurora kinase, are currently de-prioritised but offer upside potential on revived activity.

 

The autoimmune space is highly competitive (dominated by big pharma) and while PS will be the likely focus for SDC-1801's Phase Ia clinical study (easiest to recruit; potential c $40bn market, albeit a very crowded one), we expect Sareum to get better mileage from prospecting other, less explored, autoimmune conditions such as lupus ($1.9bn market but less crowded) and inflammatory bowel disease (IBD - $16bn market) where its dual action may offer greater therapeutic gains.

Click here to view the full report.

 

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Dissemination of a CORPORATE NEWS, transmitted by EQS Group.The issuer is solely responsible for the content of this announcement.


End of Announcement - EQS News Service

1192912 05-May-2021 

corporate announcement transmitted by DGAP - a service of EQS Group AG. The issuer is solely responsible for the content of this announcement.

Date   Source Headline
8th Nov 20225:23 pmRNSUpdate on SDC-1801 CTA Application
24th Oct 20227:00 amRNSFinal Results for the Year Ended 30 June 2022
12th Oct 20227:00 amRNSUpdate on SRA737
30th Sep 20224:41 pmRNSSecond Price Monitoring Extn
30th Sep 20224:36 pmRNSPrice Monitoring Extension
12th Sep 20227:00 amRNSSareum notes FDA approval of first TYK2 Inhibitor
28th Jul 20227:00 amRNSCTA application to MHRA and Corporate Update
4th Jul 20227:00 amRNSSareum notes GSK's completed acquisition of Sierra
26th Apr 20227:00 amRNSSareum to Present at BioTrinity 2022 Conference
13th Apr 20224:00 pmRNSSareum notes acquisition of Sierra Oncology by GSK
13th Apr 202211:05 amRNSSecond Price Monitoring Extn
13th Apr 202211:00 amRNSPrice Monitoring Extension
11th Apr 20227:00 amRNSEuropean Patent Granted for Sareum’s SDC-1802
8th Apr 20224:41 pmRNSSecond Price Monitoring Extn
8th Apr 20224:36 pmRNSPrice Monitoring Extension
6th Apr 20222:06 pmRNSSecond Price Monitoring Extn
6th Apr 20222:00 pmRNSPrice Monitoring Extension
16th Mar 20227:00 amRNSSDC-1801: Preclinical Toxicology Report Received
9th Mar 202211:06 amRNSSecond Price Monitoring Extn
9th Mar 202211:00 amRNSPrice Monitoring Extension
28th Feb 20223:50 pmRNSResults of EGM
21st Feb 20227:00 amRNSHalf-year Report
14th Feb 20222:06 pmRNSSecond Price Monitoring Extn
14th Feb 20222:01 pmRNSPrice Monitoring Extension
4th Feb 20227:00 amRNSPublication of Circular; Notice of General Meeting
28th Jan 20228:11 amRNSCorrection - Issue of Warrants
28th Jan 20227:00 amRNSIssue of Warrants
25th Jan 20227:00 amRNSSareum to Participate in Edison Open House Event
17th Dec 20217:00 amRNSSubscription to raise £1.63m to progress SDC-1801
16th Dec 20214:21 pmRNSResult of AGM
16th Dec 20217:00 amRNSAGM Statement
15th Dec 20217:00 amRNSIntention to grant notice - EU patent for SDC-1802
7th Dec 20217:00 amRNSAGM Update
23rd Nov 202112:57 pmRNSDirector/PDMR Shareholding
19th Nov 20217:00 amRNSNotice of AGM
3rd Nov 20213:00 pmRNSExercise of Share Options and Director Dealings
29th Oct 20217:00 amRNSAppointment of Joint Corporate Broker
25th Oct 20217:00 amRNSSareum: Final Results for Year Ended 30 June 2021
21st Oct 20218:32 amRNSCorrection - Notice of Results
21st Oct 20217:00 amRNSNotice of Results and Investor Presentation
7th Oct 202110:42 amRNSUS Patent Granted for SDC-1802 TYK2/JAK1 Inhibitor
29th Sep 202110:46 amRNSReference to SRA737 Timeline at Cantor Conference
19th Aug 20217:00 amRNSTrading Statement
9th Aug 20211:26 pmRNSSubscription to raise £1,000,000
6th Aug 20217:19 amRNSSRA737 update
30th Jul 20217:00 amRNSUS Patent Notice of Allowance for SDC-1802
19th Jul 20212:05 pmRNSSecond Price Monitoring Extn
19th Jul 20212:01 pmRNSPrice Monitoring Extension
19th Jul 202111:13 amRNSSubscription to raise £1,000,000
14th Jul 20217:00 amRNSExercise of Warrants and Total Voting Rights

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