RLM.L Regulatory News (RLM)

PuriCore plc

 ("PuriCore" or the "Company")

6 March 2013

PuriCore Partners with Onset Dermatologics

Vashe-Based Hydrogel Product for Itch Related to Atopic Dermatitis to Launch in April

PuriCore (LSE: PURI), the water-based clean technology company, today announces a marketing partnership agreement with Onset Dermatologics, a leader in the development and commercialization of prescription dermatology products. PuriCore will develop and manufacture a hydrogel dermatologic product for itch symptoms related to atopic dermatitis (eczema). The product will utilise PuriCore's patented Vashe® Wound Therapy technology. Onset Dermatologics will market and distribute this new Vashe-based formulation as Aurstat® Anti-Itch Hydrogel and as a component of Aurstat Kit, exclusively in the US beginning April 2013.

In February, PuriCore announced receipt of a 510(k) regulatory clearance from the US Food and Drug Administration (FDA) for Vashe Skin and Wound Hydrogel. Under the terms of the agreement, this clearance triggers a milestone payment from Onset Dermatologics. The agreement also includes upfront payments and double-digit royalty payments on future sales of Aurstat Anti-Inch Hydrogel and Austat Kit. All intellectual property related to this dermatologic product remains under the ownership of PuriCore.

Atopic dermatitis is a common chronically relapsing skin disorder characterized by red, inflamed, dry, cracked itching skin. According to market research by Global Business Intelligence, the global atopic dermatitis therapeutics market is valued at greater than $900 million in annual sales. The US remains the largest market for atopic dermatitis therapeutics, currently valued at greater than $400 million. About 6% of the population suffers from atopic dermatitis within seven primary geographies, the US, the UK, Germany, France, Spain, Italy, and Japan. Approximately 25 million patients in these geographies seek treatment from healthcare practitioners each year.

Michael Ashton, Executive Chairman of PuriCore, said:

"Our Vashe technology provides a strong platform for the further development and commercialisation in a variety of health sciences segments. We are confident in our ability to deliver a highly effective hydrogel to manage the itch caused by atopic dermatitis and other dermatoses, and we are equally confident of Onset's capability and expertise to successfully market and continue to grow sales of this innovative treatment."

Robert J. Moccia, President of Onset Dermatologics, said:

"This partnership with PuriCore allows us to continue to deliver products that address the needs of millions of patients suffering atopic dermatitis. By addressing their chief complaint of itch, Aurstat has become well-established in the marketplace. PuriCore's new hydrogel formulation allows us to meet the needs of our customers by offering Aurstat Anti-Itch Hydrogel alone and as part of Aurstat Kit with HylatopicPlus® Cream for convenience to patients and practitioners."

About PuriCore

PuriCore plc (LSE: PURI) is a water-based clean technology company focused on developing and commercialising proprietary solutions that protect people from the spread of infectious pathogens without causing harm to human health or the environment. The Company's products are used in a broad range of markets that depend upon effective pathogen control. PuriCore is the leading full provider of all products and services required for a safe, efficient, and compliant endoscope decontamination to protect patients in UK hospitals. The Company's products are the standard for food safety and are used for floral care in leading US supermarket chains. PuriCore also offers a breakthrough wound therapy solution to treat chronic and acute wounds including diabetic ulcers and burns. PuriCore is headquartered in Malvern, Pennsylvania, with operations in Stafford and Clevedon, UK. To receive additional information on PuriCore, visit www.puricore.com, which does not form part of this announcement.

About Onset Dermatologics

Headquartered in New York and Cumberland RI, Onset Dermatologics, a subsidiary of PreCision Dermatology, is a fully-integrated prescription dermatology company with a mission to deliver innovative therapies to dermatologists and their patients. In addition to Aurstat and HylatopicPlus, Onset Dermatologics markets the prescription brands Locoid®, Tretin-X®, Minocin®, and Clarifoam®EF to dermatologists and their allied healthcare providers. Onset is expanding rapidly through internally generated innovation, acquisitions, in-licensing, and co- marketing opportunities. For additional information, visit www.onsetdermatologics.com.

Important Safety Information for Aurstat Anti-Itch Hydrogel

Aurstat Anti-Itch Hydrogel is indicated to manage and relieve the burning, itching, and pain experienced with various types of dermatoses, including atopic dermatitis, allergic contact dermatitis, and radiation dermatitis.

The pH-neutral hydrogel also helps to relieve dry, waxy skin by maintaining a moist wound and skin environment, which is beneficial to the healing process. Aurstat Anti-Itch Hydrogel may be used to relieve the pain of first and second degree burns.

Vashe is a registered trademark of PuriCore, Inc. Aurstat, HylatopicPlus, Tretin-X, Minocin, and Clarifoam are registered trademarks of Onset Dermatologics, LLC. Locoid is a registered trademark of Astellas Pharma Europe B.V. licensed to Onset Dermatologics, LLC.

Enquiries:

Certain statements made in this announcement are forward-looking statements. These forward-looking statements are not historical facts but rather are based on the Company's current expectations, estimates, and projections about its industry; its beliefs; and assumptions. Words such as 'anticipates,' 'expects,' 'intends,' 'plans,' 'believes,' 'seeks,' 'estimates,' and similar expressions are intended to identify forward-looking statements. These statements are not guarantees of future performance and are subject to known and unknown risks, uncertainties, and other factors, some of which are beyond the Company's control, are difficult to predict, and could cause actual results to differ materially from those expressed or forecasted in the forward-looking statements. The Company cautions shareholders and prospective shareholders not to place undue reliance on these forward-looking statements, which reflect the view of the Company only as of the date of this announcement. The forward-looking statements made in this announcement relate only to events as of the date on which the statements are made. The Company will not undertake any obligation to release publicly any revisions or updates to these forward-looking statements to reflect events, circumstances, or unanticipated events occurring after the date of this announcement except as required by law or by any appropriate regulatory authority.