Ixico Regulatory News (IXI)

8 December 2022

IXICO plc

("IXICO" or the "Company")

Contract update

IXICO plc (AIM: IXI), the precision analytics company delivering intelligent insights in neuroscience, announces that it has been notified by a client that the client has decided to discontinue a phase two trial that was previously announced by the Company. While this is expected to result in a reduction in management's previously anticipated revenues for 2023 of £0.1m and a total reduction in the Company's orderbook of £0.6 million, market guidance will not be impacted.

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This announcement contains inside information for the purposes of Article 7 of Regulation (EU) No 596/2014 (MAR) as it forms part of domestic law in the United Kingdom by virtue of the EU (Withdrawal) Act 2018.

About IXICO

IXICO is dedicated to delivering insights in neuroscience to help transform the advancement of investigational therapies for neurological diseases, such as Huntington's, Parkinson's, Alzheimer's disease and Multiple Sclerosis. The Company's purpose is to advance medicine and human health by turning data into clinically meaningful information, providing valuable new insights in neuroscience by supporting pharmaceutical companies across all phases of CNS clinical research. IXICO's goal is to be a leading advocate of artificial intelligence in medical image analysis.

IXICO has developed and deployed breakthrough machine learning AI data analytics, at scale, through its remote access TrialTracker technology platform, to improve the return on investment in drug development and reduce risk and uncertainty in clinical trials for the Company's pharmaceutical clients.

More information is available on www.IXICO.com and follow us on Twitter @IXICOnews