Deltex Medical Regulatory News (DEMG)

Deltex Medical Group plc

Chairman's Statement to Annual General Meeting

28 April 2011 - At today's Annual General Meeting of Deltex Medical the Company's Chairman, Nigel Keen said.

"In the year to date we continue to make progress towards our goal of establishing the use of the CardioQ-ODMÔ as a standard of care around the world. Our strategy is designed both to support local adoption of CardioQ-ODM and to encourage the system-wide adoption of CardioQ-ODM.

Sales in the year to date are ahead of 2010, costs remain under tight control and earlier this month we announced that we had raised a further £1 million in new equity. As a result the Company has the working capital available to accelerate growth in the UK.

The UK is both our largest market and the market where our positioning of CardioQ-ODM for system-wide adoption is most advanced. Four weeks ago the National Institute for Health and Clinical Excellence ("NICE") published guidance to the NHS in England recommending specifically CardioQ-ODM for use in over 800,000 patients a year undergoing major and high risk surgery. We are continuing to work with a number of NHS organisations with the goal of substantially increasing uptake of CardioQ-ODM and the NICE recommendation not only verifies our core value proposition but is also allowing us to expand the number and scope of discussions about such implementation projects.

We continue to make progress in export markets. In the USA there is growing awareness in some of the leading teaching hospitals of the importance of active management of central blood flows during surgery and we are making inroads into a number of influential hospitals and hospital systems. In France we are supporting our distributor's efforts to capitalise on the Paris hospital system tender awarded in respect of CardioQ-ODM late in 2010. In Spain we are supporting Government sponsored CardioQ-ODM evaluation projects and we are working with hospital systems in a number of countries such as Canada and Australia towards demonstrating successful implementation of CardioQ-ODM as a prelude to potential system-wide roll-out.

The board looks forward to continued progress throughout the remainder of 2011 and beyond."

For further information, please contact:-

Deltex Medical Group plc 01243 774 837

Nigel Keen, Chairman njk@deltexmedical.com

Ewan Phillips, Chief Executive eap@deltexmedical.com

Paul Mitchell, Finance Director pjm@deltexmedical.com

Nominated Adviser & Broker

Arden Partners plc 020 7614 5900

Chris Hardie chris.hardie@arden-partners.com

Jamie Cameron jamie.cameron@arden-partners.com

Kreab Gavin Anderson 020 7074 1800

Robert Speed rspeed@kreabgavinanderson.com

Deborah Walter dwalter@kreabgavinanderson.com

Notes for Editors

Deltex Medical manufactures and markets the CardioQ-ODMÔ system. CardioQ-ODM changes the way doctors care for surgical patients allowing them to recover faster and leave hospital sooner and in better health than they otherwise would do. The performance of the system has been validated through independently conducted, randomised controlled clinical trials and is being translated into routine clinical practice in leading hospitals around the world.

CardioQ-ODM comprises a monitor and a single patient disposable probe. The probe is placed into the oesophagus through either the mouth or nose and the tip positioned facing the adjacent descending aorta. A low frequency ultrasound signal, generated by the monitor, is bounced off the blood travelling down the aorta and the Doppler principle is used to determine the velocity of the blood flow, expressed in distance per cardiac cycle - 'Stroke Distance'. The monitor also calculates the amount of time that blood is flowing down the aorta as a proportion of a cardiac cycle - 'Flow Time'.

The monitor uses a validated proprietary nomogram to extrapolate volumetric data (Stroke Volume, Cardiac Output etc) from the directly measured flow velocity. The nomogram utilises the patient's age weight and height, effectively to estimate the size of the aorta in which the velocity of the flow is being measured. Crucially this means that any reported relative change in Stroke Volume is absolutely identical to the relative change in the directly measured flow velocity variable of Stroke Distance. CardioQ-ODM immediately and reliably identifies even very small changes in the blood flow velocity allowing doctors to intevene earlier and on smaller changes than with any other approach.

Intra-operative individualised Doppler guided fluid management entails insertion and focusing of the probe to obtain a baseline reading, giving a small (200 to 250 ml) fluid challenge directly into the vascular system and seeing if Stroke Volume (or Stroke Distance) increases by more than 10%. If the increase is more than 10%, repeat fluid boluses are administered until such time as the increase is less than 10%: after this no further fluid is given unless Stroke Volume falls by more than 10% - the process is designed to achieve and maintain the individual patient's optimal Stroke Volume. CardioQ-ODM is also used during surgery to guide administration of vaso-active agents such as inotropes.

The CardioQ-ODM helps patients by enabling doctors to reduce the complications that arise from a medical condition that is common to almost all patients having surgery and many others in intensive care or arriving in the accident and emergency department. This condition is known as hypovolaemia - a reduction in circulating blood volume - and in surgical patients arises as a direct consequence of the combined effects of pre-operative starvation, the anaesthetic agents and the blood and fluid losses associated with the surgical procedure itself. Hypovolaemia means that the body struggles to get sufficient blood to the tissues and vital organs which are consequently starved of essential oxygen. This can cause medical complications including peripheral and major organ failure, which if not dealt with quickly can lead to severe compromise or even death.

There are already over 2,300 CardioQ-ODMscurrently in use in hospitals worldwide and distribution arrangements are in place in over 30 countries. In addition, there are currently more than 250 clinical publications on the use of the CardioQ-ODM which have repeatedly:-

·; Validated the results of CardioQ-ODMagainst known standards for measuring cardiac output

·; Proved that CardioQ-ODM works in a wide range of surgical procedures

·; Proved that CardioQ-ODMdelivers 50% or more reductions in post-operative complications and 25% or more reductions in length of hospital stay: better care at lower cost.

The SupraQÔis an entirely non-invasive device which uses an ultrasound probe held at the base of the patient's neck to track the flow of blood in the aorta; it presents the same data as the CardioQ-ODMin a similar format and is used for taking snapshots or monitoring over short periods.