Ampeak Energy Regulatory News (AMP)

Amphion Innovations plc

 ("Amphion" or "the Company")

Polarean Update

London and New York, 23 August 2018 - Amphion Innovations plc (AIM: AMP), the developer of medical, life science, and technology businesses, notes that its partner company Polarean Imaging plc ("Polarean") has announced that the first patient has been enrolled in its Phase III FDA clinical trial which aims to demonstrate non-inferiority of the Company's drug-device combination, using hyperpolarised 129-Xenon (129Xe) gas MRI, against an approved comparator.

This news means that Polarean is now in the process of its Phase III clinical trial. Polarean is listed on the AIM market of the London Stock Exchange under the ticker POLX.

Amphion currently holds c. 17 million shares, equivalent to 21.7% of the enlarged Share Capital of Polarean.

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About Amphion Innovations plc - www.amphionplc.com

Amphion Innovations is a developer of medical, life science and technology businesses. We use our extensive experience in company building to invest and build shareholder value in high growth companies in the US and UK. Amphion has significant shareholding in a small number of Partner Companies developing proven technologies targeting substantial commercial marketplaces. The Amphion model has been refined to optimise the commercialisation of patents and other intellectual property within the Partner Companies.