Phase 3 trail7 Jan 2025 02:11
After positive phase 2 results phase 3 began in August and subjects are to be monitored for 6months.
More below.
The first patients are now being screened to see if they are eligible to take part in the Β£2.4 million phase III trial is led by the University of Exeter. The trial will initially be delivered at eight NHS sites across the UK.
The study, called Multicentre Investigation of Ketamine for Reduction of Alcohol Relapse (MORE-KARE), is co-funded by a partnership between the National Institute for Health and Care Research (NIHR), the Medical Research Council (MRC), and biotech company Awakn Life Sciences.β―It is managed by the Exeter Clinical Trials Unit.
The latest trial builds on positive initial findings of an earlier phase II trial, which showed combined ketamine and therapy treatment was safe and tolerable for people with severe alcohol use disorder. The previous trial found that participants who had ketamine combined with therapy went from drinking every day to remaining sober 86 per cent of the time over a six-month period
Now, the new trial, called MORE-KARE, will further test this finding, with the aim of rolling it out into the NHS if the combined treatment proves effective.
https://news.exeter.ac.uk/faculty-of-health-and-life-sciences/largest-ever-trial-of-ketamine-assisted-therapy-for-alcohol-disorder-now-recruiting/