Rainbow Rare Earths Phalaborwa project shaping up to be one of the lowest cost producers globally. Watch the video here.
Https://ondinebio.com/photodisinfection-for-biofilm-joint-infections/
“This is the first study to show that photodisinfection, also known as photodynamic therapy (PDT), could be an effective novel treatment for periprosthetic joint infections. This is particularly exciting as it provides a much-needed alternative to antibiotics as resistance in biofilm-forming bacteria continues to grow. We [the research team at University Hospital Zurich] are planning a clinical safety study to further explore the potential of photodisinfection to treat and even prevent PJIs.”
Patients undergoing major surgeries like hip or knee replacements face the risk of life-threatening infections with the majority of these related to the patients’ own microflora, or bacteria naturally present on the body. PJIs are typically extremely hard to treat,[ii] often requiring surgical intervention and prolonged treatment with high-dose antibiotics. In the US alone, the annual cost of treating PJIs is estimated at $1.62 billion.[iii]
Yes you will. Absolutely no rush in this share, a lot of the big buys have been mid morning and expect the same today.
It is all good, the longer the 10-20% increases happen the better, we don't want this rocketing and dropping.
Nice and steady wins the race
RNS Number : 4499Q
Ondine Biomedical Inc.
18 October 2023
18 October 2023
ONDINE BIOMEDICAL INC.
("Ondine Biomedical", "Ondine" or the "Company")
Steriwave shown to reduce resistant bacteria by >99.9%
· New research presented by Ondine shows that Steriwave photodisinfection reduces antibiotic-resistant bacteria by more than 99.9% without generating resistance.
· The research suggests that photodisinfection is a viable alternative to antibiotics.
Canadian life sciences company Ondine Biomedical Inc. (LON: OBI) is today presenting new research showing that Steriwave® photodisinfection reduced antibiotic-resistant bacteria by more than 99.9%. The in vitro study, which is being presented today at the IP2023 Annual conference taking place in Liverpool 17-19 October 2023, indicates that photodisinfection is likely to play an important role in strategies for combatting antimicrobial resistance (AMR).
The controlled study evaluated the efficacy of Ondine's Steriwave® photodisinfection against Gram-negative and Gram-positive multidrug-resistant (MDR) and extensively drug-resistant (XDR) bacteria with novel antibiotic resistance factors. All of the bacterial strains used in the study exhibited resistance against some of the most commonly prescribed antibiotic classes, including penicillin, tetracyclines, quinolones and carbapenems.
The results of the study showed that treatment with photodisinfection resulted in >99.9% reduction of viable bacteria compared to the control, regardless of the antibiotic susceptibility of the bacteria. The authors concluded that photodisinfection is likely an important adjunct to AMR strategies in the future and that further clinical studies are warranted.
Antimicrobial resistance (AMR) remains a major public health concern, causing 33,000 deaths in Europe annually[1] which is projected to rise to over 10 million globally by 2050.[2] There are widespread multidrug-resistant (MDR) and extensively drug-resistant (XDR) infections across the world which are mainly caused by Gram-negative bacteria including Enterobacteriaceae and P. aeruginosa AMR bacteria[3],[4] and Gram-positive bacteria such as Staphylococcus spp.[5] Steriwave has been found to be highly effective against all these pathogens.
Photodisinfection uses a photosensitizer and a specific wavelength of light to trigger photochemical reactions that produce reactive oxygen species. These reactive oxygen species are lethal to a broad spectrum of microbes, including bacteria, fungi, and viruses. Importantly, photodisinfection does not induce antimicrobial resistance formation.
Carolyn Cross, CEO of Ondine, commented:
"We continue to demonstrate, both clinically in hospitals across Canada and in the lab, that photodisinfection can provide a real alternative to topical antimicrobials which are no longer effective against an increasing number of pathogens. The evidence continues to show that photodisinfection destroys all types of pat