Is b-interferon worthy of support?14 Oct 2024 11:32
While most messages here are about funding and management, nobody is asking whether b-interferon (active in SNG001) is any good and worthy of support? It is now a very old drug, generically available, originally sold by Bayer for multiple sclerosis (MS). Even though it was a drug with poor efficacy, sales peaked at $1.7bn in 2009, largely because there was nothing else for MS patients. As soon as alternatives hit the market, sales declined.
With this background and profile, institutional investors will run a mile rather than fund a Phase II trial for a weak, generic drug with an alternative administration technique. Results from trials of SNG001 to date have been really disappointing (my opinion); ignore the rose-tinted gloss from management and Holgate (totally biased) and look at the data. Investing in this phase II trial would be throwing good money away. Listed companies offering reformulations of drugs have not been successful at all. For all the same reasons, this is not going to attract a larger pharma.
Management can say all it likes, but investors/potential investors must challenge them about whether b-interferon is any good. All the evidence says: NO.
Synairgen has frittered away all the cash that it had, so there is nothing left for a private company seeking a listing to reverse into.