Member Info for maidit308

let's face it we are still very much under the radar here,
keeping the resistance up'' with so much happening in the background, and to closed blue
before any update would give the game away, IMO

we wait patiently for what ever is to come, while games are been
played on small volumes of sells,

still on target to 7 / 10 by end of the month, small daily under the radar rise
and stable is a good thing, as spike get sold into

see what tomorrow brings

it's ok to call Paul out for leaving us to the wolf for the past 2 years
after that £6m fund raise :@ 2.25p and hope he see it and do something about it ASAP
but to tell people not to buy'' and sell up there stock while SP is on it's A-SS
with lot's of contract and tie up in the bag, and i'm sure there is more to come..

is not your call to make

close at it's day high that's a very good sign that there is more to come
in the days ahead, hold tight'' the chart is pointing to 0.6p ZAK say

and there will be posters coming out of the woodwork desperate for us to sell up
for there masters, on a 18% rise and x4 PME telling the market that news
shouldn't too far away.. don't get caught up in there barre face DRAMP with CAP LOCK
FULLY ON LOL!! YES WE CAN ALL SEE YOUR POST'' NO NEED TO SHOUT..

disgusting..

308

i have a strong feeling that this is going to be our week lads & gals
all road lead to June, imminent imminent imminent update IMO,
although we are down a tad on the day, I would not worry too much
in that regards, as we could easily shoot back up before closed

we will see

GLA

excellent RNS but lets get back over fifty before we get excited
see if MH can drop some more, on work over to bring back stability to this
very undervalued stock..

nothing to worry about it's just your friendly Monday morning
beat on MOS, on low volume to get stock before big news land.

give it a chance, let it run it's course, stick to the positive

ATB

308..

not a lot to report to start our week off'' apart from this link 2 days ago to another
checkpoint COMBO for Cancer going in to P2

https://www.proactiveinvestors.co.uk/companies/news/983420/4d-pharma-outlines-phase-ii-plans-for-promising-cancer-drug-candidate-983420.html

goes to show it's all happening out there, and as SRA737 is already at P2 for solid tumor
the ball is certainly in GSK hands to get this deal over the line,
so they can progress this first in class compound ASAP..

sometime all we need is a little bit of luck, right place at the right time,
looking back at this tweet on the 13th ''spooky'' especially as we are 1 of only
2 safe TYK2 in development

Stephen Parker Retweeted
Sareum Holdings plc
@Sareumplc
·
May 13
BMS #TYK2 inhibitor deucravacitinib shows lasting two-year psoriasis efficacy and a consistent safety profile
https://fiercebiotech.com/biotech/bms-new-safety-data-psoriasis-drug-puts-company-track-third-new-drug-launch-2022
Sareum is planning to begin first clinical trials on its TYK2/JAK1 inhibitor SC-1801 later this year http://sareum.com/news/press-releases-and-news/2022/preclinical-toxicology-report-received/
$SAR.L #AIM #Biotech

BMS espect to hear from the FDA in SEPT if they get the nod for there TYK2 P3
annalist are saying, if approved, it would be the only TYK2 ever approve for any
treatment??

that awaited approval would give SAR a huge boost IMO, although still a way off
but yet another CO progress we have to keep an eye on for any update related,

anyway let's get to 1801 clinical trial first..

many thanks everyone, for all the support , in the last few hours
I'm overwhelmed''

and as i said in one of my post this week, and other posters, with the same thought
as we wait on GSK to finalize the deal with Sierra in order to get some action on 737??
our only near near near term prospect
is 1801 that we all know from what's written by the BOD, borders on a cure all compound
for any autoimmune disease.. a possible £800 bill a year Market?

what i would like to see is good posters throwing there weight around
the fast approaching possible June H2 trial of this wonder cure in 1801

try and post as much info on it that we can, and generally keep up the good sentiment
for blue sunny day every day, who knows we may even see a tweet from PARKER
or TM to help it along to £3, we know that the capsule is ready, all we need is the
date, for the biggest boooooooooooooooooooooooooooom we have ever seen in our life
and possible lot's of press, on the subject

I'm getting ready for it, there is lots of sign over the last 2 weeks,
with the stability of the SP in the £2.20 £2.30 range and MM applying resistance
to keep it there, and off course a few 1 for the believers??

''IT COULD BE YOU''

NEXT WEEK??

fingers and toes cross for all concern INC the BOD
who has seen there holdings down to 1m from 50m
like the rest of us

looking forward to another cracking week of movement & stability

ATB

308..

thanks for your support KK'' and thought's

all hell break lose, the other week when i spoke about
a new virus of concern all over the news, and they said there
is 11 cases of virus X reported, and since my post on that faithful day
the latest breaking news is that there is now 92 cases
and it remind me of COVID 19 when they said there was 3 cases reported in England
before it went out of control.. i was polite'' on that day'' the RE: was off topic...
and it was just a thought on a science subject, if our 1801 would be able to handle it
been that it's toted as a 1 stop shop for autoimmune disease
i still can't think what i said wrong

anyway, i would rather not see the few posters that's ganging up on me
for there own personal reason, than to bring this BB into disrepute,
and ultimately a drop in SP for bad sentiment, as we know MM & trolls
feed on that to pick our pockets, don't forget, it's not everyone on here
will have good intention we are all strangers behind our keypad
but one can always tell if they mean well by what they say
if you look back at history

anyway the only near term thing SAR has got going on ATM is 1801
as SRA 737 is in the hands of GSK, after the deal with Sierra is signed off,
and if they want to tell the Market anything on it's development going forward
until it's in P3 and get approval, as i think, if they think they have the holy grail
in solid tumor indication, they would want to keep it to themselves
for as long as possible... BWTFDIK

ATB

good weekend

i suppose everything 7.90p or just below are buys? just before, and after the rise to 8
but as usual they will try and hide the action, from the hawkers...
especially if they sniff news imminent..

try again next week, hopefully the bombs and missile would have run out by then
unless China is secretly supplying the electronic for making them
through the back door.. who knows?? we pray for peace..

but it's nice to see a blue end to the week and back at our 8p base

308..

thanks for your optimistic view TJ'' and on that note
we have just gone BLUE'' been a long time coming IMO,

now lets hope the power that be, keep that brake of for the last 40 minutes
for an excellent BB filled with optimism for the weekend and for what
could land next week

Regards...

could be a Friday afternoon surprise'' here goes something? or nothing?

GLA

SDC-1801 is being developed as a potential new treatment for a range of autoimmune diseases and for the acute respiratory symptoms of Covid-19.

so it's not just for respiratory ?? as suggested on here, it's a cure all DYOR

this is huge'' no silly £1.9 Bill can buy this compound
if the BOD stick to the path and get us through all the trials
we wan't to see Big Pharma mouth dribbling first if there is to be any talk

Cambridge, UK , 16 March 2022 - Sareum Holdings plc (AIM: SAR), the specialist drug development company, is pleased to provide an update on the development of its proprietary TYK2/JAK1 inhibitor SDC-1801 towards first-in-human trials. As disclosed in the Company's half-year results on 21 February 2022, the data analysis from the preclinical toxicology and safety studies required to file for an exploratory Clinical Trial Authorisation ("CTA") is complete. The Company has now received the final signed report from the Contract Research Organisation that conducted these studies and, as previously reported, these data fully support the Company's plan to submit a CTA application in mid-2022 and to commence a Phase 1a clinical trial with SDC-1801 in H2 2022.

SDC-1801 is being developed as a potential new treatment for a range of autoimmune diseases and for the acute respiratory symptoms of Covid-19.

The report confirms that the studies met their objectives of identifying any organs or tissues that might be susceptible to high-dose toxicity and determining an appropriate dose range to test in first-in-human studies.

Sareum is working with specialist clinical trial consultants to design the first clinical trial with SDC-1801. This Phase 1a trial will investigate the safety of ascending doses of SDC-1801 in healthy subjects prior to the selection of an initial indication for further clinical study in patients in any subsequent trials. The Phase 1a trial will also investigate the effect of SDC-1801 on certain biomarkers of autoimmune disease that could be predictive of efficacy when tested in patients.

In addition, the manufacture of SDC-1801 drug substance and oral capsule formulation under Good Manufacturing Practice ("GMP") conditions is on track to enable the Phase 1a trial to commence in H2 2022, pending their successful completion and the requisite CTA approval.

it's all there in black and white for everyone that DYOR
H2 is the time line, meaning half year June, give or take a day or two,
and with only 3 trading days to go after today, I'm looking forward to an early
RNS update, in that regards, if the 1801 TOX report is anything to go by, that was 3 weeks earlier
than expected..

BTW yet another full blue day of buying?? sentiment is slowly changing at SAR
and I'm sure MM will start taking the brakes off at some point
if not today 1 day next week..

ATB

308..

yes H2 even thanks PM''

that pesky UT again why we did not close blue
with buys far outweighing sells, perhaps they are saving it for a blue start tomorrow
we will see..

but with only 4 trading days left, next week WED is the start of Q2

won't be long before we hear something from the bod, IMO...

if not tomorrow?

we will see

i was saying about the desperation to get stock on that drop in my last post
considering how well 7DIG is doing on all it's contract so far''

and to get ready for the big booooooooooom BOUNCE

well here it is 71% up and climbing something is coming for sure
perhaps another big Triller like contract??

who knows?

GLA

our day is coming, a big blow out is expected any time from now''

GLA