Roundtable Discussion; The Future of Mineral Sands. Watch the video here.
Mart, I might be wrong but I’m pretty sure that phase 111 isn’t required here as doxorubicin is an established tried and tested drug. AVA6000 is a novel way of turning it into a targeted pro drug .
Listen to Thursday‘s webinar. Avacta are much further down the line than you realise.
If AVA6000 is successful in clinical trials, what is pro-Doxorubicin worth to any of the pharmaceutical giants?
Surely £10 Billion as a minimum and that’s just AVA6000.
10 billion = £40 per share.
That is not at all unrealistic within 12 -18 months. I just hope Avacta aren’t taken out in the very near term for a tenner a share.
Happy to wait 18 months for potentially £40 per share.
htTps://www.**********.co.uk/articles/paul-hill-justin-waite-with-22-stocks-to-follow-45531e8
Some really good discussions going on this morning.
I gather Alastair presented to Pharmaceutical companies after the webinar yesterday.
It’ll be interesting to see who’ll first to start taking a position and start to stake build here!
29 Sep 2021
Achievement of Pre-clinical Development Milestone in LG Chem Life Sciences Partnership
Avacta Group plc (AIM: AVCT), a clinical stage biopharmaceutical company developing innovative cancer therapies and powerful diagnostics based on its proprietary Affimer® and pre|CISION™ platforms, is pleased to announce that a pre-clinical development milestone has been achieved in the multi-target therapeutics development partnership with LG Chem Life Sciences (“LG Chem”), the life sciences division of the South Korean LG Group, triggering an undisclosed milestone payment.
Avacta and LG Chem have a multi-target therapeutics development agreement to develop Affimer® therapeutics in several disease areas. As part of the agreement, LG Chem has the exclusive rights to develop and commercialise, on a world-wide basis, Avacta’s Affimer® PD-L1 inhibitor with Affimer XT® serum half-life extension.
LG Chem has successfully completed certain pre-clinical in-vivo models in the PD-L1/XT programme leading to the selection of a pre-clinical candidate for further development towards the clinic and triggering an undisclosed milestone payment.
The partnership also provides LG Chem with rights to develop and commercialise other Affimer® and non-Affimer biotherapeutics combined with Affimer XT® half-life extension for a range of indications and Avacta could earn up to $55m in milestone payments for each of these new products. In addition, under the agreement Avacta will earn royalties on all future Affimer XT® product sales by LG Chem.
Dr. Alastair Smith, Chief Executive of Avacta Group, commented:
“I am delighted with the progress in our important strategic partnership with LG Chem. LG Chem is a world-class drug development partner with excellent biologics manufacturing and clinical development capabilities and a pioneering vision to develop innovative drugs.
“I am particularly pleased that we have achieved this significant milestone with a novel Affimer® bispecific product, which highlights the tremendous promise of the Affimer® platform.”
About Affimer XT®
Affimer XT® is a system for extending the time a drug spends in the circulation (“serum half-life extension”). Affimer XT® comprises an Affimer® that binds to a large blood protein called Serum Albumin that is too large to be cleared rapidly from the circulation. Half-life extension can be achieved by linking Affimer XT® to a small drug such as an Affimer® PD-L1 inhibitor to make a bispecific drug molecule. A small drug that might otherwise be cleared through the kidneys in a matter of hours, will remain in the circulation for many days if attached to Serum Albumin via Affimer XT®. A long serum half-life increases the exposure of a tumour to the drug and potentially therefore improves the therapeutic effect.
Sit on your hands, it’s simply not worth the gamble of being out of this share when the next few news items are released!
When HUA gets RNS’d the SP will multiply. When AVA6000 news is released the SP will multiply some more. That’s without taking into account other irons!
We could be in for one hell of a week if we get the HUA RNS and a positive update/webinar.
Then we’ve almost certainly got the end of year progress report on AVA6000.
Add/hold and glue your hands to your chairs for the next 6 months or use a longer lasting glue for even greater returns!