IMM: Portfolio of Assets13 Apr 2022 16:23
Portfolio of Assets
There are 6 key parts of Immupharma:
1. Lupuzor – Lupus (Sales Potential >$1bn per annum) Preparing to Commence Phase 3 lupus trial end 2020 / beginning 2021, with SPA application before FDA with decision imminent. Partnered with Avion who are funding the Phase 3 trial. Up to 17% US royalties, with IMM retaining 100% European and ROW rights.
2. Lupuzor (P140) – CIPD (SP >$500m per annum), aim to move into a proof of concept study. Also there is preclinical research to show that many other autoimmune diseases can be targeted including Rheumatoid Arthritis, Mixed Connective Tissue Disease, Sjogren's Syndrome, Multiple Sclerosis, Insulin Dependent Diabetes, Crohn's Disease and Bullous Diseases.
3. Metabolism – New Bioglucagon (SP $500m per annum), bio equivalence study 2021, potential launch 2022
4. Anti Infectives – New BioAMP-B (SP $400m per annum), bio equivalence study 2021, potential launch 2022
5. Nucant Cancer Programme – Phase I/IIa trial of reformulation completed 2015. The intention is to pre-treat with Nucant and then deliver the standard dose of cytotoxic drug, Gemcitabin for example in pancreatic cancer. Discussions to partner with Incanthera broke down in 2019, new partner now sought.
6. 11.9% share in Incanthera with options to buy the same number of shares again, which has a lead product Sol, a formulation designed to deliver into the skin an active ingredient known to prevent the conversion of solar keratoses into skin cancer. Confirmation announced in 2020 of exceeding bioequivalence compared with oral delivery and with statistically significant greater dermal delivery compared with four known comparator products