Silver bullet16 Jun 2020 15:11
Warning: this could come across rampy.
Just reading what I can on the steroid trial. My initial thoughts are that it was not placebo controlled, so there's that.
It was randomised but can not be blind as no placebo used.
Secondly, I find it interesting that there is a curve in the effectiveness. By that I mean when administered to those on the highest level of intervention it reduces mortality more frequently than when administered at an intermediate level (ventilation vs oxygen) then has absolutely no change to mortality rate when treatment begins early. It should be the other way around.
The same number of people who would die but the steroid would save should progress to each stage, I'm struggling to articulate, but it shouldn't be less effective when you start treatment earlier, you would still be administering it to patients as they come on to ventilation.
Be interested in everyone's views... That top line data looks good, but something a little off for me.