Member Info for Hopester

Agreed Zebbo,
This is another bombshell finding. TNBC has a very short treatment decision window.
I cannot see why FDA approval would be required to implement this technique. They are using Parsortix to capture the cells which are then observed to determine changes in the CTC structure and hence guide further treatment. Do clinicians shy away from non FDA approved techniques for fear of later difficulties / lawsuits?

Very specific. Tantalisingly close to ISA top-up day. I don't want the price going through the roof when I'm making this year's investment. Selfish, I know! GLA

I'm being selfish I know researcher, but I'd like it to stay at or below this level until 6-7th April. With that in mind, confidently expecting FDA approval on 4th April! GLA

I can see no reason why tests could not be offered to those concerned about their health and able to pay, perhaps as part of an annual check up.
The system is capable of so much more in terms of treatment monitoring and guidance, but no doubt there will be much money to be made from small labs pandering to the concerned wealthy. All IMHO

As a strategy for what GL?
Do you wish to add to your holding at a better price, or do you just want to get your prediction on record so that you can once again come back and crow about your astonishing insight in calling the bottom?
I'm sure that lots of serious LTHs on here will have limit buys in place - but they're keeping quiet about it. All IMHO.

That's quite an assumption Oilhead.
Market price action suggests that in these rattled markets, there are better opportunities for Angle speculators to turn a quick buck elsewhere.
Meanwhile, LTHs of Angle now have an opportunity to add to their holdings at a bargain price. All IMHO

Carpe Diem PJ, carpe Diem!

Exactly Dibs. A surprising drop in the SP for no obvious reason.
Great opportunity for those with knowledge, patience and nerve to fill their boots.

Do you have further info Gawd?
Is this an antigen binding detection system that is limited to the capture of non viable epithelial cells? Such systems have their applications, but do not come close to Parsortix which can capture viable epithelial and mesenchymal CTCs ready for all manner of downstream processing. All IMHO.

And it's not just PI s that are fretting and losing patience. De Walden Estates must be getting quite worked up about the delay.
A piece of top end London property, having had tens of millions spent adapting to purpose and now sitting idle must be raising eyebrows and blood pressure at de Walden.
Maybe a jumble sale would go some way to defraying the tens of thousands a month they would expect to receive in rent.
I'm sure de Walden are not being kept in the dark regarding progress.

Thompi,
How about we refer to them as 'gloateurs'?

Of one thing we can be sure - things will have dramatically changed by 6th April. I would love to get the full whack into my ISA and into AGL at these prices or lower, but I've never had that kind of good fortune.

Would accreditation be lab specific or more like a definition or specification of equipment and calibration, workflows, sample security etc?
In other words, after initial accreditation was granted, any lab set up complying with this specification, would be able to gain accreditation after a brief compliance audit. Or have I got that totally wrong?

You really put a hex on it there Sheephatch!
What's happened? A very positive RNS and yet it drops over 25%.
Has anyone figured it out?

As Daresbury is a certified nuclear research facility, I don't imagine there will be any issue with firing up the system to full beam energy for test purposes.
Part of the testing will surely be to establish the levels of stray radiation from the various components of the assembly.
Only once this is known will it be possible to apply for EA approval and calculate the amount of shielding required for safe operation.
Relocating the proven system to its final destination is likely to take many months; plenty time for EA approval.
At least I hope so!

I feel it in my bones!

Certainly not going to be popular with those doing high annual mileages.
Petrol or diesel vehicles should reliably cover 150,000 miles. With proper care, 250,000 miles should be achievable.
A petrol or diesel car typically has a 400-500 mile range and refuelling will take 5 minutes, and if you keep a can in the boot you can push on for another 30 miles if you misjudge things.
An IC car should also last at least 15 years
An EV will be unlikely to exceed 400 miles range and it's usable life is likely to be determined by number of battery discharge cycles.
The EV experience will be like driving an IC car with a tattered timing belt - just waiting to grind to a halt with a £5-20k repair bill.
All IMHO

When you think about how lockdowns have disrupted and delayed cancer diagnosis and treatment, you realise what a timebomb is awaiting us when things return to 'normal'
There will be large numbers of individuals with disease more advanced than would be optimal at the start of treatment.
It would be a tremendous advantage if treatments can be targeted to specific tumour genetic characteristics to have the best chance of success if a soaring death toll is to be avoided.
Parsortix is the only process currently available that is capable of conveniently providing this information to the oncologist after further analysis (think Thermo Fisher) and I think the FDA may be under some pressure not to drag their feet on the approval of this device..
I hope I am right, both from the perspective of the PI looking to make some profit , and the cancer sufferers whose successful treatment could depend on the information that this process can provide.
Let's hope we can all win in the end. All IMHO

I spoke to a gentleman at Bank of Scotland Sharedealing in the middle of last week as there had been no sign of activity on my VRP shares in the account. Thing were supposed to be happening on the 19th.
He advised me that there had been some delay in the ADR conversion process but that matters were in hand.
I have also noticed that my VRP shares have been removed from my account so I imagine things will be straightened out in the next few days. Good luck!

I've just spoken with a very knowledgeable and helpful lady at Bank of Scotland Sharedealing regarding the transfer process and it looks like this will not be straightforward as the shares need to transfer from X-O to B of S
Apparently the conversion to ADSs will take place on the 19th but the shares will need to be in the account by the 16th.
I asked the question regarding a late arrival of the shares and apparently dealing in VRP will cease on the 19th so if your shares arrive after the 17th, too late for conversion, you will have two days to sell them before dealing is suspended. If they arrive after the 19th, you will have ten days to transfer them back to X-O in order to sell them.
Under normal circumstances, share transfers take up to six weeks so I think I'm kidding myself that the transfer will take place within the time scale. It seems that all stages of the process depend on Royal Mail rather than electronic communication so it's likely that 4-6 weeks is not an unrealistic time scale.
It looks like the only safe option is to sell VRP, transfer the funds to B of S and then buy VRNA after the 19th.
Do you think the MMs realise this? Maybe this is why the bid / offer spread is 16%. B**tards!