Member Info for Fruitsnveg

Not invested but have been following, sounds like a lucky exit.

Doc,
I like a balanced argument, so in the spirit of factual correctness it should be acknowledged by all here that it was our current CEO, Richard J Marsden, that negotiated the 2014 AstraZeneca deal worth US$7.25mln as an upfront payment. On top of that, he negotiated a further development and commercial milestones totalling US$225mln, and up to mid-teen royalties payable on sales to boot. Not bad for a guy who you would have us believe barely understands the science or is somehow commercially inept?

If that is not a proven track record then I do not know what is. Jazz hands marketing guff (a la Ram, CEO of Relief Therapies with his thoroughly underwhelming headline 35% data readback headline in case anyone missed it ) means nothing when the product can't reach commercial viability. Richard Mardsden knows this and that's his style - substance over guff. I have faith that if he is delivered solid enough data to commercialise SNG001, he will. Everything rests in the data.

Nothing is certain. We could fail. Equally, we could succeed. But I have full faith in our CEO. As in investor, the the 2014 AZ deal delivered to shareholders proves his worth to me.

Thank you Hanoihank, I was hoping for a balanced, unemotive, factual run down, and there we have it. Agree with your summary 100%.

Scinv, read my posts from yesterday and you will understand why I see things differently to you about RM's panel discusion performance. There is nothing 'to sort out'. You see it negatively, I see it positivley, hey ho. If you are not happy with your investment you can always sell?

ScinvTemp .... one mans reality is another mans illusion.

JoeyD, I am in agreement with you, and thank you for furnishing those facts and figures as well as that data should be considered in the context of the HT. You have laid it out succinctly imo.

Yep definitley worth a re-listen to understand his comments in the context of the earlier COPD / Asthma trial results and how they were negatively affected by lack of exacerbations. Nothing more than words of caution imo. Careful we go, the tortoise and hare...

When RM referred to 'the fire to put out' imo he was specifically talking about what the earlier COPD and asthma studies done around 2016, as evidenced by AZ in their trial of SNG001. It showed that lack of exacerbations (specifically) resulted in a lower 'signal'. He then said to Max Hermann "it MIGHT be so for Covid, it MIGHT be that in the home environment that the patients aren't poorly enough to generate a big signal. Nevertheless you don't need much of an effect when the world is straining and hospitals filled up with patients".

He is not saying the HT results WILL be poor, he is stating that they simply don't know yet.

Wholly agree with your thoughts Peelweight.

they are just teasing us now with the digital countdown....

Thanks SDG27, appreciate it :-)

https://www.nih.gov/news-events/news-releases/scientists-find-evidence-novel-coronavirus-infects-mouths-cells.

Who knew? What a perplexing beggar Covid is. In light of the fact that SNG001 is inhaled, this is somewhat interesting, although early days with the science etc.

Interesting:

8th April 2021 Reuters reports
"Rheumatoid arthritis drug baricitinib developed by Eli Lilly and Co, and Incyte Corp did not meet the main goal of a late-stage study in hospitalised Covid-19 patients, the drugmakers said on Thursday. Baricitinib has been granted emergency use authorisation by the Food and Drug Administration in combination with remdesivir for Covid-19 patients requiring supplemental oxygen."

More here
https://www.marketwatch.com/story/eli-lilly-and-incyte-say-phase-3-study-of-baricitinib-in-hospitalized-covid-19-patients-failed-to-meet-main-goal-2021-04-08

Sorry you’re right Matterhorn. Long day! Ignore that Q.

Thanks for the update Matterhorn. Question -ref the USA - doesn’t the fact that the Covid@home website in US was that recently updated with pictograms and option of inhaled medicine, indicate that they are now recruiting more widely (than just Texas)? It does to me (as why else give it as an option if it’s not yet available to )? What do you think?

Excellent news on results. Just added and holding, as always, long.

Global Covid-19 cases rise for sixth consecutive week, WHO

“Global Covid-19 cases have risen for the sixth consecutive week, according to the World Health Organization’s Weekly Epidemiological Update.
Over the last week, more than four million new cases have been reported.
The South-East Asia region – most notably India – and the Western Pacific region had the largest increases in case incidence. Brazil, the US, Turkey and France followed India in the highest number of new cases.
More than 71,000 new deaths were reported over the last week – an 11% increase compared to the week before.
All regions except the African region reported increases in deaths. The South-East Asia region also had the biggest increase (46%) in new deaths.“

https://www.independent.co.uk/news/uk/home-news/chile-coronavirus-vaccine-lockdown-whitty-b1827155.html

Prof Whitty said: “Is this due to vaccines used? Is this due to the timing of when things have actually been rolled out? Is it due to particular interactions with other variants? We don't yet know.”

I think Credit Suisse would describe last week as a bit more than 'a bit of a bad week' Xviolet' :-)
Still, lessons will have been learned, at least publicly.

Thanks everyone, I asked the question not because I think it's a big deal (I personally don't). I wanted to be clear on the timing, that's all. 6th April new tax year rejigging the books etc etc.