Covid Project18 Sep 2020 11:32
1/2
Just some musings on the covid project.
From the RNS dated 16th April
Stage one (amplification of the plasmid DNA) - Starting in May, time to take fours weeks
Stage two (In Vitro) Starting in Jun, time to take 10 weeks.
Stage 3. subject to positive results being achieved at stage 2, undertaking an initial Pre In Vivo study. Starting mid-July, time to take ten weeks,
Once the stage 3 results have been reviewed, the Company will then determine whether to do a further In Vivo study to demonstrate the capability of Nuvec® to generate Covid-19 specific antibodies.
From RNS dated 28th May
Stage One completed successfully move on to stage Two. All on schedule
‘Following the recent fundraise, announced on 13 May 2020, the Company is now also exploring ways in which it can bring forward the start of certain areas of this third phase to run alongside the in-vitro work.’
From RNS 6th July
Despite Covid-19 all on track with Covid project. Again highlighted that the company ‘continues to look at ways in which it can accelerate the commencement of Stage 3 of the Covid-19 work (as set out in the Company's announcement on 16 April 2020) and perform the in vivo protein expression’
From RNS August 12th
Stage two has worked. Moving onto stage 3 Pre In Vivo study
Nigel is quoted as saying ‘We now move straight to the third stage of our Covid-19 project with our pre in vivo study at Evotec. The global pandemic continues to dominate all of our lives and we are extremely excited to be moving onto the next stage of our Covid-19 project, the successful outcome of which will determine our next work streams in this area and how we might collaborate with appropriate partners interested in any advantage our Nuvec® delivery system may provide’
‘We now move straight to the third stage of our Covid-19 project with our pre in vivo study at Evotec’ he did not say we continue with. Remember they said that wanted to try and run stage 3 alongside stage 2. This certainly could give the impression they had not started stage 3.
From RNS 14th September
Stage 3 ‘did not result in a measurable expression of the spike protein in the target cells of the murine target.’
‘The initial pilot work of stage 3 of the Covid-19 proof of concept work was narrow in its scope’
’the Company has decided to proceed to a full in vivo study to demonstrate the capability of Nuvec® to generate Covid-19 specific antibodies’
If stage 3 had not started until the end of stage two(12th August) and it takes 10 weeks to run(stated in RNS 16th April) why did we get the results only 4 ½ weeks later (Sept 14th)??
Potential answers;
1, They were so happy with stage 2 results( and Nuvec in general) they did a very quick stage 3 with proof being ‘The initial pilot work of stage 3 of the Covid-19 proof of concept work was narrow in its scope’
2, They started before the end of stage 2, which in fairness they had hoped but no clear indication th
Sign In
Follow the stocks
