RE: Collaboration; Expansion of wound care division29 Jul 2019 11:30
CBD and Pain Relief:
The human body makes its own version of CBD compounds called endocannabinoids with two receptors CB1 and CB2. They operate like neurotransmitters, switching on and off nerves. These, in turn, spark or dampen the electric pulse that creates thoughts, behaviours and movements. Tetrahydrocannabinoil ("THC"), the psychoactive substance that creates a high has a strong affinity to CB1, whereas CBD, with less than 0.2% THC does not typically interact with CB1 but can trigger a response to the body's endocannabinoids. Researchers, including Dr Joseph Cheer, a neurobiologist at the University of Maryland who specialises in cannabinoids, suggest that CBD switches off electrical pulses associated with pain by tweaking the amount of calcium that can get inside the body's nerves.
Labskin has already successfully tested CBD demonstrating anti-microbial and anti-inflammatory effects in skin-care with the Company's STOER For Men cosmetics products, and is currently testing CBD infused female hygiene products at the Company's Labskin test facility in York, UK.
Wound Care Growth:
The incidence of chronic wounds is growing with approximately 1-2% of the USA population sustaining chronic wounds during their lifetime, leading to approximately 6.5 million incidences at an annual cost of approximately US$25 billion. In Europe, wound management costs approximately �6650-�10,000 per patient and consumes 2-4% of European healthcare budgets.
Patients with diabetes are also at high risk of wound infections. Approximately 387 million people have diabetes, and this number is predicted to increase by 205 million by 2035.
Collaboration partners
Labskin (Innovenn Ltd - wholly owned subsidiary of Integumen)
Integumen's laboratory grown human skin testing services. Specifically developed to host harmful bacteria on simulated human skin. It is the best testing platform for antimicrobial products, such as anti-dandruff shampoos and anti-acne creams, anti-aging, anti-fungal, UV sun exposure, toxic shock, and drug delivery through the skin, which cannot currently be carried out in vivo (animal models) due to ethical constraints of testing harmful bacteria.
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