Member Info for BULP

thank you. every time a relative got cancer I always bought shares here after they had passed away , now have just over a million shares here. every time I look at the screen I am aware of a lot of dead people looking at the sp over my shoulder. I always remember my father in the hospice refusing to give in , walking endless lapses of the corridor with his drip trying to get fit , and at the end of the week seeing him on his lap with a small troop of terminal patients all following behind him. when this comes in I shall raise a glass to him and the others who are not here. news soon

hello thoth 2 just saw your 13:45 post , yes the thought had crossed my mind as well . been her since my father was dying of small cell lung cancer 16 years ago , when I was looking for any treatments for him . I sense that something big is in the pipe line and that news is due soon . the Chinese will make a move on this and very soon indeed.

as taken from sareum company site ,
JAK inhibition can block IFNa/? signalling and thus restores GM-CSF levels. However, GM-CSF signals via JAK2, indicating that a JAK2 inhibitor is likely to counter the beneficial effects of GM-CSF level restoration. This suggests a JAK inhibitor that inhibits JAKs other than JAK2 would be optimally beneficial, and Sareum's SDC-1801 fits this profile, inhibiting TYK2 and JAK1, but not JAK2.

Whilst developing SDC-1801, we have produced compelling cellular and in-vivo data in models of autoimmune disease to demonstrate the beneficial effects of SDC-1801 in modulating the key cytokines involved in the cytokine storm phase of Covid-19. Details can be made available to potential funding, collaboration and/or licensing partners on request.
surely research must have started ages ago and is well on its way to a successful conclusion. if not it would beggar belief , emailed tim but away from office till 4th august.

do you have a list of any other companies the famous 7 operate . I want to spend the weekend researching while I wait for eua to sell . thank you.

£2.00

well done every one . a great day. go to 1min 25 , headphones on and volume up to max. enjoy.
https://youtu.be/OnoNITE-CLc

China’s CanSino Biologics has released results from the Phase I trial of its Covid-19 vaccine — data that have propelled its entry into Phase II more than a month ago.

In a paper published in the Lancet, the biotech reported that their adenovirus-based vaccine was “tolerable and immunogenic at 28 days post-vaccination” among the 195 volunteers enrolled in the trial. In addition to antibody responses, T cell responses were also observed.

“Humoral responses against SARS-CoV-2 peaked at day 28 post-vaccination in healthy adults, and rapid specific T-cell responses were noted from day 14 post-vaccination,” the researchers wrote.

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The most common adverse reactions were fever, fatigue, headache and muscle pain.

The publication followed a promising snapshot from Moderna on its mRNA vaccine candidate, although the US biotech didn’t break down the numbers.

Like Moderna, CanSino has dropped the highest dose and will be comparing the low and middle doses with placebo in Phase II. People over the age of 60, who weren’t eligible for the first-in-human study, were also enrolled.

The CanSino candidate employs a recombinant adenovirus type-5 (Ad5) vector to encapsulate a SARS-CoV-2 spike glycoprotein to elicit an immune response — a technology they’ve previously used to develop an Ebola vaccine.

Toward the end of what otherwise reads like a usual scientific paper, the scientists made note of the urgency their work carries:

Many vaccine candidates are in rapid development, including recombinant-protein based vaccines, replicating or non-replicating viral vector-based vaccines, DNA vaccines, and mRNA vaccines (which mostly have focused on the spike glycoprotein or receptor binding domain), live attenuated vaccines, and inactivated virus vaccines. All of these vaccine platforms have advantages and disadvantages, and it is too soon to predict which will be more successful.

The study was conducted in Wuhan, ground zero of the global pandemic, in March and April.

i wonder if we are involved in this vaccine.
. Covid-19 roundup: CanSino beats Moderna to publication of first-in-human data for a coronavirus vaccine

I was wondering, that as sierra have not got a bean to progress our sra737 , if sareum/icr and cruk have approached our Chinese partner to take over sra737 . I would be disappointed if they have not. . good day today. stay safe .

a nice video from cdc in china about a vaccine by September . video is from april this year.
https://youtu.be/gMINUvYr4EA

I wonder if can sino is our partner in china.

that didn't work so here is the article.
Trump advisor Navarro asserts China is withholding data to win vaccine race
On Sunday, White House advisor Peter Navarro took to Fox News to accuse China of taking a suite of actions to worsen the ongoing coronavirus crisis.
“First of all, the virus was spawned in China. Second of all, they hid the virus behind the shield of the World Health Organization. The third thing they did was basically hoard personal protective equipment and now they’re profiteering from it,” Navarro said on Fox News program Sunday Morning Futures.
The outspoken critic of China, who has been tasked by President Trump to work on supply issues relating to the pandemic, on Monday suggested on Fox News that the country is withholding data about early coronavirus infections in order to be the first to develop a vaccine.
“One of the reasons that they may not have let us in and given us the data on this virus early, is they’re racing to get a vaccine and they think this is just a competitive business race, it’s a business proposition so that they can sell the vaccines to the world,” he said.
The race to develop a vaccine has heated up, with China’s CanSino as one of a handful of developers with a vaccine in human testing. — Natalie Grover

Society needs to pitch in to shore up drug, vaccine manufacturing; Trump advisor Navarro suggests China is withholding data to win vaccine race ?
interesting article , click on link then scroll down to article about Navarro , suggesting that china has info on virus and is keeping it quite to produce a vaccine or treatment to make a fortune.

just read it , oh my god our inhibiter and our partner , icr are named. our drug and another kills cancer. well done , now I know why we are rising like a rocket. time for a Peroni .

my brother has a friend who lives in Moscow, married to a Russian woman with links to fsb. this backs up the word on the street in Moscow. I was surprised that covid 19 had the same infection mechanism as hiv when the virus came out , as at the time it suggested that that could only happen in a lab and had to be spliced on to an existing virus. what a sad world. I hate socialism , right wing and left wing Nazis are just as bad as each other . lets hope for a cure soon .

one of the Chinese doctors who blew the whistle and subsequently died of the virus did mention the death rate in Wuhan at just over 42,000. it will be more now.

at the moment the earth has changed its orbit and is closer to the sun , but thankfully the sun has few sun spot activity so is less hot , the earths magnetic field has weakened as the poles start to shift , magnetic north is in Siberia , and will eventually shift so north becomes south and south becomes north , due to a weakened magnetic field the earth is being subjected to more intense solar radiation which is affecting the upper atmosphere which with a shift in the earths tilt which has already happened is causing the jet stream to shift south pushing storms and thus wetter weather , violent storms being brought up from the equator affecting the northern hemispheres weather . the increase in solar radiation is also affecting the earths crust so more earthquakes and volcanic activity . hab has already started, our concern should be global cooling / ice age . one day 70 million English will thunder back in to north Africa looking for a place to live. probable why they prefer to keep the public in the dark .

can you please send me the link please, joneill@sthelens.ac.uk. been here for 10 years or more.

is your calc just for Saudi or worldwide.

Signing of New Drilling Contract www.investegate.co.uk/article.aspx?id=201705300700114788G&fe=1