Member Info for bobfraeberks

Well, looks like my scenario is a wee bit oot! Off to hunt down a haggis ot two pre AGM disaster.

2 pm Numis

Time to highlight what I believe was the beginning of HOPE for LTIs:

Brysoa: SNG/UKHSA7 Apr 2024 12:14

I wonder what we might learn from the up-coming joint UKHSA/SNG poster presentation at the Microbiology. Society Annual Conference in Edinburgh on Tuesday. It covers work done at Porton Down with SNG001 tested in-vitro against a range of SARS-Cov19 variants. Replicating in-house sponsored testing in 2022, yes, but hopefully providing external validation of the “variant-agnostic” thesis. See A368 at: https://microbiologysociety.org/static/e2a41dbb-eafd-4056-89611c63c97bd6c7/AC24Poster-abstracts-booklet.pdf

ELSOL: RE: SNG/UKHSA8 Apr 2024 13:23

I'm not getting too excited but FYI (importantly) I did connect on LinkedIn during Oct 23 with the new Director General Science and Research (CSO) at UK HSA to flag my serious concerns about emerging mutation cracks within the UK's wider PP vaccine and therapeutic strategy and mentioned SNG001 as a specific illustrative case of wider thx. agnostics being somewhat ignored at great potential future PP risk. I sent a detailed follow-up email at the time with full detail of said concerns. Amanda Horton is acquainted to the CSO in LinkedIn. Senior Scientist / Project Team Leader at UK Health Security Agency

Dec 2021–Present 2 yrs 5 mos

Senior Scientist in the U.K. Antiviral & Therapeutics Task Force and current lead virologist of the antiviral lab team based at Porton Down. We conduct research into the efficacy of antivirals against SARS-CoV-2 variants, seasonal coronaviruses, influenza and other priority pathogens as part of the UK’s pandemic preparedness strategy.

Doc83...will do my best...but normally fail!!!

Dippfs: I take your point on funding source/timing. However, I still expect MHRA involvement thru soft funding for the CDRC and possibly some more. The MHRA 24/25 plan was released on 7 Oct and SNG001 would be a good start. The govt will want to be utilising the recent £400m framework and also showing preparedness for protection against viruses...I hope!

Doc.Daneeka Final attempt at …to get p

Doc83: I expect a RNS pre AGM but post government announcement. May include notice of the EGM. Question would be how to price the offering without knowing the market reaction. Big question for the BOD…what seriously helpful steps are you taking to protect existing shareholders?

See you Thursday

Get p

Doc.Daneeka "Looking forward I'm interested in the same thing. What are the diagnostics - and the specific viral clearance data - that suggests an MV trial will succeed. It's a punt as far as I can tell at the moment - but I'd like to see the workings out and have better confidence in the future of SNG001."

Completely agree. I would also like to see sizings of the commercial opportunity focused

1. On only MV patients

2. Wider opportunities if successful with MV.

I question why we have escalated from a smaller trial (SS 27 Jun24) to a large trial (RM 26 Sep24). A small trial would probably require less dillution and be completed quicker (long enough to get p

I still believe that the timing of this AGM has been dictated by the requirement to meet UK government requirements as I believe there will be a press release on Wednesday or Thursday morning by the UK government that will beneficially involve SNG001. I can think of no other reason for the Incredible Delay.

The timetable for transmitting forecast rounds from the OBR to the Chancellor to inform her policy decisions and for publishing the final Economic and fiscal outlook is as follows:

• Thursday 19 September: Round 1

• Tuesday 8 October: Round 2 of 5 - Two days prior to our AGM.

Responsible officials would need to know that appropriate funding was assured.

I expect this announcement will be directly linked to the 28 August UK government announcement:

“World-first public-private collaboration launched to kickstart economic growth and build an NHS fit for the future.

The Voluntary Scheme for Branded Medicine Pricing, Access and Growth (VPAG) Investment Programme opens today. It will channel significant investment into the UK’s health and life sciences sector over the next 5 years, boosting economic growth and the global competitiveness of the UK’s life sciences sector.

The funding will be channelled into key health and life sciences projects across the country to:

• increase opportunities for patients to participate in commercial clinical trials: the programme will allocate 75% of its investment to expand the UK’s capacity and capability for commercial clinical trials. Up to 18 new Commercial Research Delivery Centres (CRDCs) will be established across the 4 nations to enhance and build upon the UK’s commercial clinical trials infrastructure and support patient recruitment into trials. Researchers will also have increased access to the latest equipment and technology to enable innovative trials to be designed across hospital and primary, community and residential care settings, bringing research to communities across the UK”

I expect Southampton University will be appointed a CRDC for respiratory diseases.

We have been essentially informed that there will be a “fund raise”. It is an essential requirement that full disclosure is made prior to the pricing of this. Dilution is almost inevitable but without new investment we LTIs have essentially nothing. I expect the SP to initially rise on the news prior to dilution. I expect an EGM will be called (two weeks’ notice is required) and that TFG will provide a guarantee. There will be invovement from one of the Universal BPs.

I also anticipate involvement from BARDA. That “third place” has been open for a considerable time.

If I’m even close to being right, SS deserves a standing ovation!

GLA

I am more and more positive that good to great news is going to beak very soon. They clearly have the financing lined up and I still believe the timing is due to the UK govenment and the budget...and I include in this the press release of a few weeks ago announcing joint government and private funding for medical resarch (up to £500 over five years ). My guess is a minimum of UK Gov, BP, (possibly Astra) and the guys with 28.2%. I'm not ruling out BARDA. Dillution does not bother me at all. Something is always better than nothing...we just need the MV trial to succeed...nothing else matters.

At the last AGM,SS was critically asked as to why he was still the Chairman when he was well over the corporate guideline (9 years I think).

He responded that he felt the need to get Synairgen sorted before he was able to leave.

Recalling this makes me hopeful that the little goodies he has been dropping are real and for our benefit.

I would add that I see little reason for negotiating the exit of PM, a man he worked with for many years, if he did not see a clear, financed path for SNG.

See you on Thursday the 10th…celebrating like feck I hope.

Aether. I think you should include me with the rest of the positive thinkers! Cheers

A wee thought…the Budget is at the end of October and I expect will be finalised in early October. I expect new financial commitments will be restrained until departments are sure of their funding. Could this be the reason for our incredible delay.

I’m still generally positive but it’s squeaky bum time in the words of a fellow Scot. I can’t recall if the auditor has to sign off the interim accounts or not but as a general precaution should we on this board have a backup plan to pull our shareholdings (in terms of voting) should we be delisted or an attempt to take us private. I don’t know how we would do this but there are certainly better brains and know how here than I can offer

SlamDunk1. I believe Thusday is the preferred wwekday ( only a Friday and weekend left to meet the 15 month rule from last AGM which was Thursday 29th June 2023). In terms of the update, SS and Consillium would not be risking their reputations by needlessly delaying the AGM unless this was to the "benefit" of investors. SS has been Savills CFO (mkt value £1.6B) for around 15 years...he is not going to risk that kind of reputation on a tiddler like SNG. We'll soon see if I'm calling this completely wrong , but I am now a very large (if a wee bit short!) holder.

I expect the RNS calling the AGM will come tomorrow with the AGM on Thursday 26th September (2024!). Also, a moderately comforting update from SS.

Great find Brand. I’m hoping this is the primer for SNG trial news.

Mani. I messaged CCM on two occasions last week but did not receive a response. I asked if they were entirely comfortable with the delay in calling the AGM. I support your proposal.

No RNS today, so I will now likely miss the incredibly late AGM, unless its delayed to the week of Monday 19 August!!!

The new government has been in power for basically one week and, I expect, finding it difficult to grant/loan? to a commercial company. However, SNG must call the AGM at some point and would have to be forthcoming with reasons for the incredible delay. It might not look good if they did not support a medical and financially viable plan that had been agreed pre election...and then some new virus hits. Still feeling positive.

Dippfs I agree. SNG needs the full financial picture released to investors, including , I hope, government support in order to determine the new market value before pricing a capital raise. Should still be beneficial to LTIs