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Sierra Oncology is still conducting trials of SRA737 in combination with other agents, such as gemcitabine and cisplatin, for patients with advanced solid tumors123. The acquisition by GSK does not affect the ongoing trials of SRA737, as GSK stated that it will support the development of Sierra Oncology’s pipeline of targeted therapies45. However, the monotherapy trial of SRA737 for advanced cancer has been closed and did not show any partial or complete responses26. Therefore, the future clinical development of SRA737 will likely focus on combination therapy with other agents that can induce DNA damage and synergize with Chk1 inhibition.
Learn more:
1. cancerresearchuk.org
ARIA also supports clinical trials by allowing researchers to add trial regimens and study drugs to the system, as well as track patient enrolment and data collection3. SRA737-02/CANC30498 is one of the trial regimens that has been added to ARIA for the Thames Valley Cancer Network1.
Learn more:
1. cancerresearchuk.org
2. research.manchester.ac.uk
3. clinicaltrialsreg
Has anybody else noticed the silence from Stephen Parker and his associates in regards to todays RNS surely they are not in one of those periods when an offer is being put to them
Silly me according to Puma and his alter ego we are DOO---MED
The cost of a phase 1a/b trial in Australia can be as much as 5 million Australian dollars I would assume that Sareum would have had to prove they had the finance hence reason for borrowing.
So we are not happy with the way things are proceeding but they probably had no choice.
If Sareum was a big traded share it would probable have got the overhang out of the way by now
So all we can do is wait hope and pray that trials are going well and we get rewarded
Hi, this is Bing. I found some information about **Nucleus Network** and **SDC1801 TRIAL**. Nucleus Network is Australia's largest Phase 1 clinical trial provider with facilities in Melbourne, Brisbane and Minneapolis¹². SDC1801 is a drug being tested by Nucleus Network for the treatment of chronic kidney disease⁴. Is this a mistake
Source: Conversation with Bing, 24/08/2023
(1) Nucleus Network | Advancing medicine, improving lives. https://www.nucleusnetwork.com/.
(2) Blackstone to Acquire Nucleus Network, Australia’s Largest Phase One .... https://www.blackstone.com/news/press/blackstone-to-acquire-nucleus-network-australias-largest-phase-one-clinical-trials-specialist-2/.
(3) Melbourne Clinical Trials - Nucleus Network. https://www.nucleusnetwork.com/au/participate-in-a-trial/melbourne-clinical-trials/.
(4) Nucleus Network (Melbourne) | Australian Clinical Trials. https://www.australianclinicaltrials.gov.au/clinical_trial_sites/628.
(5) Has anyone done a medical study with Nucleus Network? : r/brisbane - Reddit. https://www.reddit.com/r/brisbane/comments/qfwreo/has_anyone_done_a_medical_study_with_nucleus/.
(6) Melbourne Clinical Trials | Nucleus Network. https://www.nucleusnetwork.com/participate-in-a-trial/melbourne-clinical-trials/.
Bluenose
Sareum have been waiting for nearly 2 years to get trials progressing now
to do this they need funding ( if trials are successful) the share price will rocket
The last thing they need is to run out of money so they had to accept whatever was put forward
Although they would have prefered a better solution it was not available
Now if they sail through the early trials it is odds on they will be taken out so the short downturn in share price will be a thing of the past
In regards to SRA737 it keeps being stated that it is a dead duck well Professor Harrington has been testing 737 with GEM. up till a couple of months ago and states it is worth carrying on with trials.
He is the head man at cancer research so lets see where it takes us
We have been here before so just keep calm and stop reacting to Laurel and Hardy
Straight forward RNS everything good going forward I expect a big Pharma will either take us out or come to an agreement to takeover trials in the next year
So all looking good just taking time to come to fruition
Now that the noise has calmed down the facts are.
We needed to raise monies from somewhere otherwise we would have been bought out at a very low price in my oppinon this is the best way forward.
Now we can sit back with the certainty that we have the funds to advance to the next phase and when this happens perhaps a suitable price will be offered for our portfolio.
Have no doubt when we start dosing the big boys will not want to allow their contempories to get in first.
So our next step hopefully will be news of 737 if this does not happen we will not be sitting waiting for funds we can keep dosing till news arrives on 801
So keep the faith do not let the TROLLS rile you just ignore them
To put this into perspective we sit on this share for months with no more than a few dozen trades all of a sudden there is many more trades.
My take is this firstly I believe it is Thoth2 family getting rid of the holding
Secondly if not Thoth there is another forced seller out there
The good thing is that there are buyers so we are at least holding at around 90 to 100p
We are waiting on news regarding 801 so until we ( please god) get this good news stop fighting among yourselves and chill out
We have been low before and the first sign of a good rns we will rise
Sadoldgit yesturday I put forward the theory that it was Thoths family that were selling his holding ,otherwise I believe the price would have risen quite sharply
The problem is that Thoth allegedly held over 2% of shares they will take a lot of shifting.
Anyway lets get a bit of news and see where it takes us.