(Sharecast News) - London's FTSE 250 was down 0.7% at 20,960.34 in afternoon trade on Tuesday.
Investec was knocked lower by a rating downgrade at Goldman Sachs.
Going the other way, Diploma rallied after the specialist seals and controls maker said full-year results were expected to "materially exceed" expectations after a strong contribution from acquisitions.
Plus500 rallied after the online trading platform said full-year revenue was set to be ahead of current market expectations as it posted a 68% jump in first-quarter revenues.
Fund management group Liontrust Asset Management pushed higher after it reported an 8.5% increase in funds under managements to £33.5bn as at the end of March.
FTSE 250 - Risers
Diploma (DPLM) 2,792.00p 11.15%
Ferrexpo (FXPO) 188.90p 8.31%
Plus500 Ltd (DI) (PLUS) 1,571.00p 6.22%
Tullow Oil (TLW) 59.95p 5.45%
Moneysupermarket.com Group (MONY) 179.60p 3.82%
Liontrust Asset Management (LIO) 1,288.00p 3.37%
Darktrace (DARK) 459.40p 2.91%
Trustpilot Group (TRST) 154.30p 2.39%
Savills (SVS) 1,100.00p 2.33%
Trainline (TRN) 283.80p 2.20%
FTSE 250 - Fallers
Investec (INVP) 499.30p -6.99%
Safestore Holdings (SAFE) 1,313.00p -5.88%
Greencore Group (CDI) (GNC) 121.50p -5.08%
TUI AG Reg Shs (DI) (TUI) 228.90p -4.66%
Premier Foods (PFD) 119.60p -4.01%
Capital & Counties Properties (CAPC) 165.50p -3.89%
Hiscox Limited (DI) (HSX) 944.40p -3.85%
Marshalls (MSLH) 643.50p -3.81%
Hammerson (HMSO) 32.40p -3.49%
Auction Technology Group (ATG) 990.00p -3.32%