Shire Share News (SHP)

LONDON (Alliance News) - The following stocks are the leading risers and fallers within the main London indices on Thursday.----------FTSE 100 - WINNERS----------Shire, up 2.3%, The Irish drugmaker said that it has secured approval from the US Food & Drug Administration to expand the offering of Cinryze to children aged six years and older with hereditary angioedema, a rare disorder characterized by recurrent episodes of severe swelling. Cinryze has been approved in the US since October 2008 for routine prophylaxis against attacks in adolescents and adults living with hereditary angioedema. The company said Cinryze is the first and only therapy indicated in the US to help prevent angioedema attacks in pediatric patients with hereditary angioedema as young as six years. The approval was based on data from a dedicated Phase 3 multicenter single-blind study that evaluated the use of Cinryze in 12 patients living with hereditary angioedema aged seven to 11. ----------FTSE 100 - LOSERS----------United Utilities, down 4.4%, Land Securities, down 1.7%. The stocks went ex-dividend meaning new buyers no longer qualify for the latest dividend payout.----------FTSE 250 - WINNERS----------Dixons Carphone, up 3.9%. The mobile phone and electronic goods retailer said its business has "so much more to go for" despite posting a drop in annual profit. For the year to April 28, pretax profit fell to GBP289 million from GBP404 million the year before. Adjusted pretax profit was down to GBP382 million from GBP500 million year-on-year, in line with the company's profit warning in late May. At the time of the May warning, Dixons said it expected profit to fall as a result of declining market conditions, reduced profit margins, and expensive network contracts in the UK. Group revenue for the year increased by 3% to GBP10.53 billion from GBP10.25 billion the year before, driven by a good international businesses growth. On a like-for-like basis, group revenue increased 4%. "Dixons Carphone has elegantly demonstrated the art of guidance. Having carefully laid the groundwork last month with a warning, today's news has boosted the share price," said IG's Chris Beauchamp. ----------CYBG, up 2.5%. JPMorgan raised the challenger bank to Neutral from Underweight believing its merger with peer Virgin Money will be "highly accretive". JPMorgan said the CYBG-Virgin Money deal is a "highly accretive merger" for CYBG, with the combined group trading at 9.6 times its 2020 price to earnings ratio, and this falling to 8.2 times when expected synergies are delivered. This is in comparison to CYBG trading at 12.7 times on a standalone basis. The combination of the two FTSE-250 listed banks will see Virgin Money shareholders receive 1.2125 new CYBG shares for each Virgin share, valuing each Virgin share at 371 pence. The offer values Virgin Money as a whole at GBP1.70 billion, and will give the combined entity a value of around GBP4.40 billion. Virgin Money was up 2.0%.----------FTSE 250 - LOSERS----------Big Yellow Group, down 3.0%. The stock went ex-dividend. ----------OTHER MAIN MARKET AND AIM - WINNERS----------Dalradian Resources, up 52% at 81 pence. The Ireland-focused gold miner said that it has agreed to a CAD537 million, or GBP306.7 million, cash acquisition offer by private equity firm Orion Mine Finance. Orion will acquire all of the issued and outstanding common shares of the company by way of a statutory plan of arrangement under Canadian corporate law. Under the terms of the agreement, each Dalradian shareholder will receive CAD1.47 in cash for each Dalradian share. The price tag represents a 62% premium to the closing price of Dalradian in Toronto on Wednesday. Shareholder BlackRock, which owns 10.7% stake in Dalradian has agreed to vote in favour of the Orion deal. Directors and senior officers of Dalradian also have agreed to support the deal.----------Trakm8, up 16%. The telematics & data supplier said it agreed to supply telematics-based services to Intelematics Australia. The company said it will provide automotive diagnostics and a 4G self-fit on-board diagnostic devices to Intelematics over the next three years. The demand over the period is expected to amount to 40,000 connections. At the end of August last year, Trakm8 partnered with the Royal Automobile Club of Victoria, a parent company of Intelematics, with which it still holds a contract. ----------OTHER MAIN MARKET AND AIM - LOSERS----------LPA Group, down 25%. The LED lighting systems maker said profit rose moderately in the first half of its current financial year, but its order book has declined since the start of the second half. The company reported pretax profit of GBP987,000 for the six months to the end of March, up 1.1% from GBP976,000 made in the same period a year earlier. Revenue was 29% higher year-on-year at GBP13.9 million compared to GBP10.8 million. The result was driven by the company's "exceptionally" strong order book at the start of the year, LPA said. However, over the course of the first half, the order book shrank, to GBP16 million on March 31 from GBP21.6 million at the end of September. Looking ahead, the company said it has invested GBP1.0 million in processes and automation to reduce manufacturing costs. In addition, it has invested in new products development and in opening new markets. LPA warned on potential challenges ahead, as its order book is declining. ----------Akers Biosciences, down 10%. The screening and testing technologies company confirmed legal action has been taken against it relating to several matters. Akers noted recent press reports over possible class actions by parties "purporting to seek to recover losses" incurred by shareholders. It also noted other class actions reported in the press, which it said had not yet been received. The class action covers the period from May 2017 to early June this year, and Akers said it will "vigorously" defend itself, as will Chief Executive John Gormally and Vice President for Finance Gary Rauch. Akers said the lawsuit relates to issues filing its quarterly report on the Nasdaq, the departure of Co-Founder Raymond Akers in May, as well as announcements by Akers its results reports for 2017, and that year's second and third quarters could not be relied upon.----------