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Share Price Information for Sareum (SAR)

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Share Price: 24.25
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Change: -1.00 (-3.96%)
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Open: 25.25
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Sareum cancer drug candidate gets MHRA trial approval

Tue, 05th Apr 2016 12:33

(ShareCast News) - Sareum Holdings was pressing ahead with one of its cancer drug programmes on Tuesday, having received approval from the Medicines and Healthcare products Regulatory Agency (MHRA) for the Clinical Trial Applications submitted for CHK1 inhibitor drug candidate CCT245737.The AIM-traded specialist cancer drug discovery and development company said that, subject to final NHS approval, clinical trials were expected to begin in the second quarter of this year.It planned two Phase I clinical trials in cancer patients in collaboration with co-development partners, the CRT Pioneer Fund.One trial would use the drug candidate in combination with standard-of-care chemotherapy and would ultimately target lung and pancreatic cancer patients, while the other trial would use it as a single anti-cancer agent and would initially target various cancers."This approval for CCT245737 is another significant milestone along its path to being the first from our development pipeline to enter clinical trials," said Sareum CEO Dr Tim Mitchell.Sareum's board also confirmed that it had satisfied a financial commitment of of £797,500 to the funding of the trials in December, and the submission of the Clinical Trial Applications triggered the receipt of a £200,000 success milestone payment from Cancer Research Technology to Sareum.
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7 Dec 2023 14:31

UK shareholder meetings calendar - next 7 days

Friday 8 December 
Amedeo Air Four Plus LtdAGM
Ashoka India Equity Investment Trust PLCAGM
Associated British Engineering PLCAGM
Associated British Foods PLCAGM
Corcel PLCGM re disposal of 41% interest in the Mambare nickel/cobalt project
Hargreaves Lansdown PLCAGM
URA Holdings PLCGM re closing the fundraise
Monday 11 December 
IamFire PLCAGM with vote on name change to WeCap PLC
Pharma C Investments PLCGM re allowing investments in fintech, AI sectors
SigmaRoc PLCGM re reverse takeover
Tribal Group PLCGM re cash offer by Tiger Bidco 1 Ltd
Vela Technologies PLCAGM
Tuesday 12 December 
Atalaya Mining PLCEGM re redomiciliation to Spain from Cyprus
Blackrock Greater Europe Investment Trust PLCAGM
Distil PLCGM re placing and subscription
Gelion PLCAGM
Wednesday 13 December 
Dechra Pharmaceuticals PLCAGM
Limitless Earth PLCAGM
Softcat PLCAGM
Volution Group PLCAGM
Thursday 14 December 
Aeorema Communications PLCAGM
CleanTech Lithium PLCGM re equity raise approval
Driver Group PLCFull Year Results
eEnergy Group PLCAGM
Ethernity Networks LtdGM re authority to allot shares on non-preemptive basis
Fintech Asia LtdAGM
Helium One Global LtdAGM
Marwyn Value Investors LtdAGM
Quarto Group IncGM re cancelling trading on London's Main Market
Sareum Holdings PLCAGM
  
Copyright 2023 Alliance News Ltd. All Rights Reserved. 

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23 Nov 2023 14:28

IN BRIEF: Sareum Holdings draws down on equity prepayment facility

Sareum Holdings PLC - Cambridge, England-based pharmaceutical company, focused on developing kinase inhibitors to treat autoimmune diseases and cancer - Says that it has drawn down on the GBP300,000 second deposit in respect of a previously announced equity prepayment facility.

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9 Nov 2023 13:47

EARNINGS AND TRADING: MetalNRG hails Gold Ridge findings

(Alliance News) - The following is a round-up of earnings and trading updates by London-listed companies, issued on Thursday and not separately reported by Alliance News:

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3 Nov 2023 13:59

Sareum secures Japan patent for kinase inhibitor asset

(Sharecast News) - Biotechnology firm Sareum announced on Friday that it has received a notice of allowance from the Japan Patent Office for a patent associated with SDC-1801, its primary TYK2/JAK1 kinase inhibitor.

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3 Nov 2023 09:01

Sareum says patent notice in Japan boosts confidence in SDC-1801

(Alliance News) - Sareum Holdings PLC on Friday said it received a notice of allowance from Japan's Patent Office for a patent relating to its lead TYK2/JAK1 kinase inhibitor, SDC-1801.

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9 Oct 2023 15:06

Sareum losses widen as clinical trials continue

(Sharecast News) - Biotechnology company Sareum Holdings reported a loss of £3.2m after tax in its final results on Monday, widening from last year's £2.2m due to heightened expenses from initiating clinical studies with SDC-1801, despite aligning with market anticipations.

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9 Oct 2023 10:58

Sareum says earnings down but product development going well

(Alliance News) - Sareum Holdings PLC on Monday said its annual loss widened and its cash reserves are substantially reduced, but that development and testing of its medicinal products is progressing well.

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6 Sep 2023 14:35

Director dealings: Blackbird, Sareum insiders pick up shares

(Sharecast News) - Blackbird found itself with a number of entries on the list of director buys on Wednesday, after a number of insiders and associates bought shares.

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4 Sep 2023 09:18

Sareum begins dosing participants in phase 1a trial for SDC-1801

(Alliance News) - Sareum Holdings PLC on Monday said it has successfully started the multiple ascending dose part of its phase 1a clinical trial for its SDC-1801 drug, following approval from the safety review committee.

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16 Aug 2023 13:13

Sareum flagship drug trial progressing well ahead of annual results

(Alliance News) - Sareum Holdings PLC on Wednesday said a clinical trial for its main therapeutic is continuing as planned, and it hopes to use a new prepayment facility to further enhance development.

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3 Aug 2023 14:16

IN BRIEF: Sareum secures GBP5 million of funding from RiverFort Global

Sareum Holdings PLC - Cambridge-based biotechnology company developing kinase inhibitors for autoimmune diseases and cancers - Agrees terms on equity prepayment facility of up to GBP5 million with RiverFort Global Opportunities PCC Ltd, as arranged by RiverFort Global Capital Ltd, with an initial deposit of GBP2 million. This is expected on August 4, net of associated costs.

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26 Jun 2023 17:33

TRADING UPDATES: New patents for Sareum; Guanajuato hails assessment

(Alliance News) - The following is a round-up of updates by London-listed companies, issued Monday and not separately reported by Alliance News:

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26 Jun 2023 10:54

Sareum granted new patents in China, US

(Sharecast News) - Clinical-stage biotechnology developer Sareum announced the granting of patents for its lead kinase inhibitors in China and the United States on Monday.

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6 Jun 2023 13:36

IN BRIEF: Sareum doses first subjects in psoriasis drug trial

Sareum Holdings PLC - Cambridge-based biotechnology company developing kinase inhibitors for autoimmune diseases and cancers - Announces successful dosing of first test subjects in a randomised, placebo-controlled phase 1a clinical trial for lead programme SDC-1801. SDC-1801 is a dual TYK2/JAK1 kinase inhibitor and potential new therapeutic for various autoimmune diseases with an initial focus on psoriasis. The phase 1a trial will investigate the safety, tolerability, pharmacokinetics and pharmacodynamics of SDC-1801 in healthy subjects, in single and multiple ascending oral dose studies. Dosing has started in a specialist clinical unit in Melbourne, Australia. Sareum expects full safety data to become available during the first half of 2024, after which a phase 1b clinical study will commence post-haste if the Phase 1a trial obtains satisfactory results.

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18 May 2023 14:31

TRADING UPDATES: Nuformix says NXP002 shows anti-inflammatory effect

(Alliance News) - The following is a round-up of updates by London-listed companies, issued on Thursday and not separately reported by Alliance News:

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