(Adds Aveo, Zafgen, Alkermes, Sirius; updates Eli Lilly,Pioneer Natural) (For faster updates on individual market-movers, Eikon usersplease use search string "STXBZ US"; for the Day Aheadnewsletter, http://link.reuters.com/mex49s; for the Morning NewsCall newsletter, http://link.reuters.com/nex49s)
U.S. stock index futures rose on Wednesday, putting Wall Streeton track to bounce from a five-day slide, ahead of data on thelabor market and the minutes from the most recent meeting of theU.S. Federal Reserve. Dow Jones industrial average futures were up 0.88 percent at 17,443, S&P 500 futures were up 0.88 percent at 2,012 and Nasdaq 100 futures wereup 0.80 percent at 4,135.
** ZAFGEN INC, Tuesday close $32.17, +8.80 pctpremarket
The company said a mid-stage study showed its experimentaldrug reduced weight in patients obese due to damage to a part ofthe brain. The drug, beloranib, was tested against a placebo in14 adults with obesity resulting from damage to the hypothalamusfollowing surgery to remove a kind of brain tumor.
** ALKERMES PLC, Tuesday close $60.93, +5.01 pctpremarket
Alkermes said its experimental drug to treat schizophreniamet the main goal in a mid-stage trial. The drug, codenamed ALKS3831, combines samidorphan and the antipsychotic drug,olanzapine.
** SIRIUS XM HOLDINGS, Tuesday close $3.35, +1.19pct premarket
The satellite radio service company said it would beat its2014 revenue forecast of $4.15 billion after net subscriberadditions exceeded expectations. The company reported about 1.8million net subscriber additions for the year, above itsincreased forecast of 1.5 million.
** AVEO PHARMACEUTICALS INC, Tuesday close $0.84
The company doing business as Aveo Oncology said it plannedto cut two-thirds of its workforce, or 40 positions, as part ofa restructuring that includes the departure of Chief ScientificOfficer Jeno Gyuris.
** ELI LILLY AND CO, Tuesday close $69.72, -1.03 pctpremarket
The drugmaker, whose earnings have been battered in the pastthree years by competition from generic medicines, forecast 2015revenue shy of Wall Street expectations.
** PIONEER NATURAL RESOURCES, Tuesday close $139.46,+0.89 pct premarket
Topeka Capital cuts its target price to $158 from $200 onthe oil and gas producer's stock after the company said it hasrestructured most of its 2015 hedge position to protect againstfurther falls in oil prices.
** KALOBIOS PHARMACEUTICALS INC, Tuesday close$1.83, -65.03 pct premarket
KaloBios Pharmaceuticals said it would discontinue thedevelopment of its drug for lung infections in cystic fibrosispatients after it failed in a mid-stage study.
** J.C. PENNEY CO INC, Tuesday close $6.56, +22.10pct premarket
The department store operator said same-store sales rose 3.7percent in November and December, boosting its shares andoffering a glimpse of what is expected to be the best holidayseason for retailers since.
** VERIZON COMMUNICATIONS INC, Tuesday close$47.04, -0.40 pct premarket
** AOL INC, Tuesday close $46.25, -1.62 pctpremarket
Verizon Communications CEO Lowell McAdam said the companywas not planning any major acquisitions, following a report thatVerizon had approached AOL for a potential deal.
** FIAT CHRYSLER AUTOMOBILES NV, Tuesday close$11.59, +0.69 pct premarket
Jeep, the SUV brand that is key to Fiat Chrysler's global expansion plans, narrowly met its goal of selling onemillion vehicles in 2014, the Jeep brand chief said on Tuesday.
** KEURIG GREEN MOUNTAIN INC, Tuesday close$127.19, +3.17 pct premarket
** SNAPPLE GROUP INC, Tuesday close $71.48, -100.00pct premarket
The maker of the K-Cup single-serve coffee pod, signed adeal with Dr Pepper Snapple Group to sell capsules that make itssodas in Keurig's planned cold-drink machine, the Wall StreetJournal reported.
** ROYAL DUTCH SHELL, Tuesday close $63.02, +0.94pct premarket
The Anglo-Dutch oil company will pay out 55 million pounds($83.4 million) in compensation for two oil spills in Nigeria in2008 after agreeing a settlement with the affected community.
** INTEL CORP, Tuesday close $35.28, +1.28 pctpremarket
Chief Executive Brian Krzanich showed off a computer builtinto a jacket button and a wristband that transforms into aselfie-snapping flying camera, as the chipmaker extended itspush into smart wearable gadgets.
** APPLE INC, Tuesday close $106.26, +0.76 pctpremarket
Audio equipment maker Monster LLC has sued Beats ElectronicsLLC, owned by Apple, over alleged "fraud and deceit" in the wayBeats acquired control of the rights to the popular "Beats byDr. Dre" headphones.
** MICRON TECHNOLOGY INC, Tuesday close $32.87, -1.73pct premarket
The memory chipmaker gave a quarterly revenue forecast onTuesday that missed Wall Street's expectations, hurt by anoutput drop as it upgrades DRAM production lines, and its sharesfell.
** CONTINENTAL RESOURCES INC, Tuesday close$33.59, +1.82 pct premarket
CEO Harold Hamm, embroiled in a bitter divorce, offered topay his former wife $974.8 million, but she rejected ahand-written check, lawyers for both sides said on Tuesday.
** AMAZON.COM INC, Tuesday close $295.29, +0.65 pctpremarket
Crowdsourced fundraising site Kickstarter has droppedAmazon.com as its global payments processor in favor of Stripe,the fast-growing startup used by Twitter Inc, FacebookInc and Apple Inc.
The switch comes as the Internet retailer begins to moveclients from its customizable checkout service to anAmazon-branded one.
** MONSANTO CO, Tuesday close $116.25
The world's largest seed company and purveyor of geneticallyaltered seeds and Roundup herbicide is expected to issue itsfirst-quarter earnings report before markets open on Tuesday.
** SUPERVALU INC, Tuesday close $9.19
The supermarket chain is expected to report results onWednesday before markets open.
** BOEING CO, Tuesday close $127.53
Airbus Group beat the planemaker in aircraft ordersin 2014, maintaining a lead in new business despite lagging indeliveries, a person familiar with the matter said on Tuesday. (Compiled by Lehar Maan; Editing by Joyjeet Das)
