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Pin to quick picksGlaxosmithkline Share News (GSK)

Share Price Information for Glaxosmithkline (GSK)

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Share Price: 1,744.50
Bid: 1,744.50
Ask: 1,745.00
Change: 11.00 (0.63%)
Spread: 0.50 (0.029%)
Open: 1,736.00
High: 1,750.00
Low: 1,736.00
Prev. Close: 1,733.50
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More work needed for mepolizumab application, says GlaxoSmithKline

Mon, 10th Sep 2018 07:22

(Sharecast News) - GlaxoSmithKline has received a 'complete response letter' from the United States Food and Drug Administration regarding its application for mepolizumab, it announced on Monday.The FTSE 100 firm said it had submitted for mepolizumab to be used as an add-on treatment to inhaled corticosteroid-based maintenance treatment, for the reduction of exacerbations in patients with chronic obstructive pulmonary disease, guided by blood eosinophil counts."The [response letter] states that more clinical data are required to support an approval," GlaxoSmithKline said in its statement."GSK will work closely with the FDA to determine the appropriate next steps for the supplementary biologics licence application."The pharmaceuticals giant said mepolizumab was approved in 2015 for severe eosinophilic asthma, and was also licenced for EGPA in the US.It described it as "the first-in-class" monoclonal antibody that targeted IL-5."It is believed to work by preventing IL-5 from binding to its receptor on the surface of eosinophils," GSK explained."Inhibiting IL-5 binding in this way reduces blood eosinophils."Mepolizumab had been studied in more than 3000 patients in 16 clinical trials across a number of eosinophilic indications, and was currently being investigated for severe hypereosinophilic syndrome and nasal polyposis, in addition to the supplementary biologics licence application filed for the treatment of patients with chronic obstructive pulmonary disorder.
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1 May 2024 17:31

UK's FTSE 100 slips ahead of Fed outcome, energy stocks weigh

FTSE 100 down 0.3%, FTSE 250 off 0.2%

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1 May 2024 16:56

LONDON MARKET CLOSE: FTSE 100 down ahead of US interest rate decision

(Alliance News) - Stock prices in London closed mostly in the red on Wednesday, as investors eye the latest interest rate decision from the US Federal Reserve this evening.

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1 May 2024 16:42

London close: Stocks fall ahead of US Fed decision

(Sharecast News) - London markets closed lower on Wednesday, as investors digested the latest UK manufacturing data and anticipated an impending policy announcement from the US Federal Reserve.

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1 May 2024 11:55

LONDON MARKET MIDDAY: FTSE 100 treads water as Fed takes centre-stage

(Alliance News) - London's FTSE 100 traded off session highs heading into Wednesday afternoon, as some pre-Federal Reserve decision nerves kicked in.

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1 May 2024 10:54

GSK raises profit outlook on strong vaccine, HIV drug sales

FY profit forecast raised to 8-10%

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1 May 2024 08:57

LONDON MARKET OPEN: FTSE 100 shakes off New York slump before Fed

(Alliance News) - Stock prices in London opened mixed on Wednesday, with the FTSE 100 brushing off some pre-Federal Reserve decision trepidation to record an early rise, while the dollar climbed on the expectation that Jerome Powell will sound hawkish in his press conference later.

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TOP NEWS: GSK expects momentum to continue after strong first quarter

(Alliance News) - GSK PLC on Wednesday raised its annual earnings forecast, and said it expects sales growth at the top-end of guidance, after a "strong" start to the year.

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LONDON BRIEFING: GSK ups outlook; Next first-quarter beats forecast

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First trial over Zantac cancer claims set to begin in Chicago

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First trial over Zantac cancer claims set to begin in Chicago

April 30 (Reuters) - The first trial over claims that blockbuster heartburn drug Zantac, once sold by GSK and other companies, causes cancer is set to begin this week in Chicago.

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