* FTSE 100 scores longest winning streak on record
* Pan-European STOXX index ends up 0.2 pct
* Trump comments on drug prices hits healthcare stocks
* Mediaset rallies on report of Vivendi boss offer (Live coverage of European markets now available on cpurl://apps.cp./cms/?pageId=livemarkets. Adds details, closing prices)
By Danilo Masoni and Helen Reid
MILAN/LONDON, Jan 11 (Reuters) - European shares ended offhighs on Wednesday as pharma stocks turned lower on worries overpricing pressure in the U.S. following remarks by Donald Trumpin his first news conference.
Europe's index of healthcare stocks fell 0.7percent, weighing on the region's benchmark STOXX Europe 600index which inched up 0.2 percent at the close.
In spite of the turn into negative territory of drug stocks,Britain's blue-chip FTSE 100 rose 0.2 percent to a newrecord high, closing higher for the twelfth consecutive sessionin its longest winning streak in the index's 33-year history.Cumulative gains however over the period were limited to 3.5percent.
The U.S. President-elect commented on the need forcompetitive drug pricing saying pharmaceutical companies are"getting away with murder" by charging high drug prices.
London-listed drugmakers Shire and Astrazeneca fell 3.2 percent and 1.8 percent, leading losers intheir sector, while Swiss heavyweights Novartis and Roche bothfell more than 1 percent, causing the SMI index to endwith a drop of 0.3 percent.
Elsewhere, retail stocks were back in focus after awell-received update from British grocer Sainsbury.
Sainsbury's shares rose as much as 7.8 percent afterBritain's second-biggest supermarket beat forecasts forunderlying sales in its Christmas quarter. Thestock however ended off highs with a gain of 1 percent.
This followed peer Morrison's strong performance inthe previous session after it too reported robust figures.
"UK supermarkets seem to be in rude health following bullishstatements from both Morrison's and Sainsbury's," said IGanalyst Josh Mahony.
Mediaset rose 5.9 percent, topping gainers on theSTOXX. Traders cited a report that Vivendi chiefVincent Bollore could offer a stake in the French media group tothe Berlusconi family in a bid to end a dispute over control ofthe Italian broadcaster.
Another outstanding gainer was Danish bioscience company ChrHansen following consensus-beating first-quarterearnings. The stock rose 5.1 percent.
But British aero engineering firm Cobham fell 14.9percent, after it missed its profit target and scrapped itsfinal dividend.
Cobham's 2016 trading profit fell short of a target it hadcut just two months before the end of the year because of poortrading. It was headed for its worst day ever, through nearlythree days' trading in mid-morning.
UBS equities analysts said a recent change in management,with a new CEO and CFO, meant further revisions were likely oncenew managers undertake a deep review of the business. (Additional reporting by Kit Rees)