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What is the possible significance of this change, if any? Just for my understanding.
A terrible, cruel disease. Condolences to his family and friends all.
Yes, sad news indeed RIP John.
I remember one AGM when someone asked a question about the SP. He dismissed it with distain saying “the BOD have absolutely zero control over the SP. Next?”
That stuck with me and over the years has stopped me getting too worked up about the SP.
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Sad news indeed R.I.P.
Whereas the conspiracy theorists and bad mouthers who speculated maliciously on the reasons for his departure will.
Life is very unfair. R.I.P. John Chiplin.
It's a shame that he will not be around to witness Scancell's endgame.
Sad news to hear of John Chiplin, than you for sharing.
May he rest in peace and indeed much thanks to his support . He must have been really pleased with results coming through. What an incredible person, all the best to him family at a difficult time x
Thanks for sharing that berm .. very sad indeed .. can see him now chairing an agm .. what a shame .. thanks to him for shouting scancells corner and I guess it’s clearer now why he left ..
Take care ..
What a very sad announcement from Scancell this afternoon. MND is a dreadful disease and I'm sure all Scancell holders would wish to send sincere condolences to John's family and friends.
https://www.scancell.co.uk/it-is-with-great-sadness-that-scancell-announces-the-death-of-former-chairman--john-chiplin
I've listened a number of times to the last 1.5 minutes of the interview.
I've flip-floped a number of times on what she's actually thinking / saying.
Thanks Burble , thought that would be the case
have you Listened to Seth's recent Presentation which I have posted before , mentions this is an excellent presentation
https://www.youtube.com/watch?v=-kF_G22FANE
1.6 mins in
Epitope small cell lung cancer with Scib
2. 8 mins in positive differences and advantages of the Scancell Melanoma vaccine over personalised and off the self offerings . The concern of the NHS hospitals and logistics of treating patients for 2 years ( storage etc)
3. mentions the Glymab Platform .
Posted yesterday :
On Linked in post from Scancells research scientist Bubacarr G Kaira :
Glycans are important and can be considered as the icing on the cake.
And in the context of glycan mediated disease, understanding the function of glycans on proteins is key. Additionally, glycans are aberrantly overexpressed on cancer cells and targeting these glycans as strategy to kill cancer cells is essential and Scancell Ltd is a leader in producing anti-glycan antibodies (#GlyMab) against cancer cells.
Fortunately, some very prominent conferences like ISABS are taking place in Croatia, so I do not have to travel far... Recording of my yesterday's plenary lecture "Glycan biomarkers for personalized preventive healthcare" at the 13th Congress of the International Society for Applied Biological Sciences is available here.
With the following presentation , which listen to understand just how important Glycol are
From professor Gordon Lauc
Prof Gordan Lauc: Glycan biomarkers for personalized preventive healthcare
https://www.youtube.com/watch?v=_LrS9my_ioQ
Burble, yes they are using biopsy samples from patients...
"The main aim of this study is to assess the sugar-lipid distribution pattern on the cancer cells in SCLC cases in order to find which patients with SCLC might benefit from antibody therapy. We need to collect lung biopsy samples from patients being investigated for possible lung cancer so that we can look at any cancer cells in the laboratory and analyse them for the presence and distribution of the sugar-lipid."
Moonparty, looks like they’ve previously applied for ethics approval to access and work with human tissue. I assume leftover pathology slides for IHC.
Found this from last year relating to SC134. I'm sure it's been posted here, but it's the first time I've seen it:
https://www.hra.nhs.uk/planning-and-improving-research/application-summaries/research-summaries/distribution-of-antibody-target-in-small-cell-lung-carcinoma/
Excellent . it really is glymab time ,
Great news. Also narrows down the possibilities of the mab under investigation by the major pharma?
Yes well spotted DeAar - thanks for posting.
Excellent find. Scancell are clearly serious about progressing this.
Ripley at 4.15 we haven't nudged up let alone made 11p, so that was a waste of time. A bit of chat has always been accepted here, it's the mischief that's the pain.
Ciaskin and Violin, yes the Govt seems to be besotted with Moderna but I suggest that's as a result of the perceived success of their covid vaccine rather than being due to favouritism because of past connections to Sunak. Of course a dose of cynicism is helpful but atm cynicism seems to cloud most comment which is unhealthy in itself.
Ciaskin, agree totally. The government has sold the UK future to Moderna and most likely your NHS health data as well . Is there a link between this and Rishi's Moderna investment...surprised if not !!!