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Thanks TRA1,
There are a surprising number of papers by Dr Coverley and co authors on this research, in addition to other authors. So i will never even hope to find/read them all. This quote stood out in one of them though.......
"Conclusions. Unexpected and unusual molecular structure of CIZ1b in native plasma has complicated immunoassay design, and delayed translation of this promising biomarker. However, CIZ1b can now be measured using a high-throughput, hospital-friendly sandwich ELISA format, overcoming an important barrier to further clinical development and application of this blood test for early stage lung cancer."
Dr Coverley is clearly a very intelligent person, and this is her life's work.
Your previous comments re shareholding also caught my attention.
You are quite correct in that the big holders are funds etc. In my business, i have had dealings with Finance Yorkshire (now known as Mercia) on a number of occasions, and it is quite telling that they elected to take an equity stake in CIZ, and a fair sized one at that, rather than a purely capital/interest repayment schedule.
Their eligibility criteria requirement for this type of investment means they are expecting a significant return.
Speaking on a purely personal level, I,m not really so interested in what the share price will be on Friday, as it will be influenced by
1.The new listing
2. Day traders buying in and selling immediately
3. Existing holders that just want their money back after such a long time in suspension etc.
I am far more interested in where this is going over a longer term.
Neil
yes the PSL board still exists -:)
It has for every other share I've had that's changed it's ticker - including THIS one - we used to be a different ticker as LTH's know!
just a thought, will a new share discussion chat start automatically when the new ticker comes into play on friday does anyone know?
Excited for Friday morning. Lets hope for a rush of buys to drive the price up nicely. GLA
CIZ
Couldn't locate this anywhere. What's our new three/four letter tag upon admission? Not BOU but .....?
Presentation:
https://www.youtube.com/watch?app=desktop&v=EUfqP-9eaSM
We will get a great one 100% it will mention readmission
We could have a nice surprise waiting for us at 7.00AM 14th, a RNS with some information about the company which they have not wanted to release until then, just to give the sp a nice little boost.
Aspen
80% discount means 500% upside potential, not counting the potential for takeover or JV and other future developments. I do expect the first day of trading will be the lowest price you will get with news flow on many milestones, (Manufacturing partner, currently in discussion, Licencing partner, CE, FDA approval, NHS collaboration). That is short/medium term.
However, if this turns to be the "biomarker of choice" for Lung Ca. similar to PSA for prostate Ca or CEA for bowel Ca; both developed to be THE mainstream tests for screening, follow up after treatment. Then, we will have a breakthrough medical discovery, sky is the limit (no hype, only scientific here), hence the multiple global patents.
p.s. Neil, since you started your journey through the medical journals, here is a little Sund. present, only a 5min read -:),
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5832880/
Just shows the potential, enjoy the rest of W/E
80 % discount to peers ..that says to me get some " have cash ready " for the first day trading !
We will be listed at 80% discount then other biotech companies that’s one of the many reasons I have few bob prepared for next week Friday. Quiet confident we will rise significantly. Only one co in the world has the test for a lung cancer it’s CIZZLE! Potential is no brainer. Apart from this I’m still ****ed that we waited so long in this nightmare and we didn’t make it 10 or 20 bags straight like we all dreamed but we will soon. I could write poems how I’m annoyed but it won’t change anything. Looking forward for a listing day it will be a really positive and exciting day! GL all
Agreed.
I've sat on the AIM darling of 2015 - XTR for 6 years waiting for it to come good - green shoots this year! :-)
As from 8.00AM 14th, we need to look at the bigger picture going forward, why wait all this time and then not give BOU/CIZZ the chance to develop.
Aspen
the shareholders list (page 5,7 of the prospectus) does not give the impression that any of them is selling on admission. Most of them are Universities, charity research funds etc). AG as far as i understand is not selling anytime soon, he is not here for 20% or so, he will prbly exercise his warrants which will add cash to the company. So to a large extent the sp on admission is more or less controlled by us PIs. There are a lot of other investors waiting to buy on admission, so If we do not sell, the sp rises, simple. We waited long time, why not give it 3-6 months frame, remember iqai from 1 to 14 (yes 14x) within 6m 2019 while awaiting for certification and fda?
LeddachJack
Completely agree with you mate, always better to have something rather than nothing.
Aspen
Next Friday will be like a Christmas bonus. Not sure how much you will get but you know it will be more than nothing!
Hi all, I am hoping by next friday 4.30pm we will all be smiling and reaching for the Champagne as the price hits 20p ??? so lets hope I am right and all us long term holders get a reasonable reward for our patience not that we had much choice, so everything crossed ??, Regards DM
Let's hope because we are all pleasantly surprised.
Aspen
next Friday! :-)
the Chinese link will be strong going forward!
I also think "CIZ" could be massive. I doubt that it will be just lung cancer that can be detected early, CIZ could help to early identify a number of be a number of cancers.
They have enough money for now. The earliest time they can do some fund raise it’s in the second half of next year( it’s in prospectus)!!! no one said they will do it of course. We will be in pounds by then! IMO they have something big to announce very shortly. Imagine in the future when they will be approved first time in history for a quick early detection lung cancer tests via blood test!! It’s a no brainer. I have couple ££££ to put on relist day if mm’s will allow me to buy it... I sense many will be surprised of market reaction :-))
re - someone mentioned Grail it was Allan Syms himself ! your description of events is about right even tho you had probs ! thanks
Agree -:
This has the potential to be MASSIVE.
So, i get in tonight and was 5 or so minutes late in joining the webinar, I was sitting here, laptop on my knee, when halfway through, the damn thing overheated (blocked the fan vent with my knee!) and shut down. By the time i registered again to join, i had missed certain parts.
From what i can see on the comments, i think there is a misconception that we are 2 years away from anything. This is not true. What Allan said is that we are fully funded for the program for the next two years - quite a different thing.
As for "not having a product yet", again i think that is incorrect. We already have a test, but we are looking for CE / FDA marking TO COMMERCIALISE it. Also, he did stress the different revenue streams. One being the licensing of our technology. Something that can be done now. In fact i think that this route is already in progress.
Someone mentioned Grail. This is spin out company (sound familiar?) from Illumina.This was one of the companies i was researching last year, as they were due to IPO on the market around the time we were speculating about the possible target, and issued a prospectus for $100millioin. As it turned out, the IPO wAs pulled, and Illumina bought their own company back for the sum of $8 BILLION That' a hell of a re-rate. They clearly saw the value . Now, just think, what if sometime in the future they bought us too, given that we are in the same market.
I said we were going into an exciting target, and i am more than happy with what i see. .
This has the potential to be MASSIVE.
Neil