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Ah Ray, you must read the AG thread in another place to know that I give my grandchildren silver coins - or have I said as much here also and it has slipped my mind? Or perhaps you post under a different handle on the AAZ thread, also in another place. I will say that the least risky investment anyone can make is physical silver and gold in your own possession and definitely not stored in any bank.
I loved everything I read here about the science and I particularly appreciated Ananaco's explanations - he seemed to know as much as the scientists themselves. However (there's always an however, isn't there?) the time frame just kept getting moved further and further out and since I'd already had my fingers burned once in similar situation, I chose to sell.
As for me posting here, well every time I raise my head above the parapet I seem to set the cat amongst the pigeons ha ha. Not everyone liked what I had to say a few years ago, and I do believe my views about big Pharma were seen as very controversial, and it has to be said my views on cancer charities did not go down well. But thank you anyway and I sincerely wish you luck here.
I was in much the same position as yourself with SCLP. I was just in profit and thinking of selling. Instead I decided to learn more about the science. The more I learnt, the more I appreciated that Scancell has a world class scientist as CSO. I suppose you could say I am in awe of the science and the rate it evolves, albeit, I do realise that I am not a scientist in the area of cancer research. This is a risky investment (infinitely more so than the silver coins you give to your grandchildren) but I do believe that the constant evolution of the science mitigates the risk to some extent. We all tend to put a positive spin on our investments ("Confirmation Bias" as Knowelsi would say) but I genuinely believe Scancell have a great chance to make a real difference especially with Moditope.
By the way, I share your attitude towards big pharma. You ought to post more often ATB
Glad you found my post useful, though you will be aware yourself, having been in PRM that the great hopes and dreams sometimes come to nothing, with a loss to boot. Although I got out of SCLP when I was still winning, I was not boasting because I didn't make enough there to boast and I certainly had no intention of 'rubbing people's noses in it', as I think Chelsea suggested.
Mabel, refreshing to read an honest opinion. You are not alone in those thoughts by any means, and particularly I have considered the points you raise, which were fuelled 8 years ago by a Senior Consultant I spoke to 8 years ago accompaning my late mother to a hospital appointment, in relation to Pharmas and small Biotechs.
Interestingly though Scancell have never even suggested having a cure, was it not RG that said our aim is to treat cancer as a chronic condition. I have only read on two occasions the word cure. One was in a recent TV Documentary where James Allison, the Nobel Prize winner said we are not too far away from being able to use the word cure, what he meant by not too far away I have no idea.
The other was on another Biotech BB where many claimed a cure, even after failing to meet primary endpoints in trial, lol.
I feel confident we will find our level in the Cancer chain, and see a very good return (eventually) but yes of course it is very high risk. ATB and Take Care
"Why did Proteome fail?" Well, I have to admit I relied on the explanation of the science by those more knowledgeable than I am. - a bit like here really, but ultimately I think the management of the company is accountable. The conditions that PRM was going to address were innumerable, but it never quite materialised. There was always an explanation forthcoming which sounded reasonable, and I watched like a rabbit in the headlights as the share price dropped and dropped. The rest is history.
I have no doubt that the products both PRM and SCLP have to offer are good products, but there are always obstacles and hurdles thrown in by way of big Pharma to stop a small biotech from taking away a lucrative earner. Profits are made by TREATING cancer, not CURING it.
I am distrustful of the pharmaceutical industry to provide a level playing field for the benefit of those who are ill, if whatever is going to affect their bottom line. Not a scientific explanation Ray, but my own honest one.
Mable, Enjoyed your post, you should do it more often! I too was invested in Proteome, I think I lost money but all memory has been erased. At the time of the Proteome hype peak, I guess people were warning about other Biotechs who had Crashed. I suppose many argued that Proteome would be different. I note the same is happening now. ATB
Interesting post Mabel. PRM's share price chart over the last 5 years looks very familiar to anyone invested in scancell. Diggle is an investor in a very risk sector, you win some and loose some. Let's hope he is due a winner.
In terms of Dr Ney, hard to get too excited at this stage - hope this is a shake up & a kick up the backside for those on the BOD. Would be happy to see other changes, one can hope. It has been too comfortable and cosy for too long. It's all about patient recruitment now, at current pace will take well over a year to recruit 6 patients needed for dose escalation. More centres are needed asap and I hope there is a sense of urgency. PRM's 6m market cap should be warning sign, we need to crack on.
Hard to argue against a fact and it's very depressing to see SCALP at this level. But our "products"are very different and some shares do "win" . It's a gamble with some great science behind the dice. Let's hope for some recovery and forward momentum.
I was invested for many years in Proteome, and Martin Diggle was a regular poster on the ad fvn thread. I soaked up the enthusiasm for that particular biotech, and what the company was going to achieve. It was mind blowing, but it was all jam tomorrow. The share price was about 120p as I remember at its height and is now a little less than 2.5p and I certainly lost money there. Not as much as some however, some of PRM's investors lost everything including their homes.
I experienced similar enthusiasm here at Scancell but fortunately saw the writing on the wall while I was still winning. Now, I would be very reluctant to invest in another biotech no matter what they were promising, and I see the same pattern happening here as happened to PRM with a constant drip, drip, drip down until it is little more than a penny. I would suggest Martin Diggle's involvement might not be as exciting as some think.