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Itsnpretty simple to see/check/test during the day
Yes
Laura, are you saying that all the 1.48 trades during the day were buys?
1.48p was the buy price at the time
Its a contra ,meaning net =zero
Two delayed trades gone through 9.20 am just popped up now each 201k volume
Not showing buy or sell.
Https://www.share-talk.com/traders-cafe-with-zak-mir-bulletin-board-heroes-tuesday-23rd-april-2024/
On the yearly chart....
SP seems to be holding the 200DMA....Good sign.
Thanks msuk
If people can invest rather than trade it will be ideal
Eg someone bought ladt thing on Friday and sold 1st thing Monday for a loss,yet 2 days later it orse 15% more ...silly
1.55 break will signify break of the 200 ema ,significant
https://invst.ly/14ikpb
This almost describes perfectly PYC target market
With the increasing investigation of DNA damage response / PARP inhibitors, alone or in combination with chemotherapy or immunotherapy, there is a need for minimally invasive, robust and repeatable DDR assays. All the development work continues to add to the menu of assays owned by ANGLE that we can offer to other customers."
The DDR therapeutics market was estimated to be valued at US$5.9 billion in 2022 and is projected to reach US$10.4 billion by 2031 with a CAGR of 6.5%1. This is expected to be driven by an increase in the use of combination therapy for the treatment of drug-resistant cancers and the need for novel targeted medicines for cancer treatment. Most cancers rely on the DDR pathway to a greater extent than healthy cells. Treating patients with a DDR inhibitor alongside another cancer drug helps to maximise DNA damage and selectively kill cancer cells. This provides a targeted approach to cancer treatment with the potential to improve patient outcomes across multiple tumour types.
Interesting developments at fellow bio tech AGL
Could well be PYC next to form this type of partnership? (Alongsode our work with merck)
ANGLE plc (AIM:AGL OTCQX:ANPCY), a world-leading liquid biopsy company with innovative circulating tumour cell (CTC) solutions for use in research, drug development and clinical oncology has signed a supplier agreement with the global biopharmaceutical company, AstraZeneca PLC, to develop and validate a methodology leveraging ANGLE's existing DNA damage response ("DDR") assay for the detection of micronuclei in CTCs as a measure of DDR
Thanks Ralph
Link to Biotrinity.
https://twitter.com/hashtag/BioTrinity?src=hashtag_click
Buying has been good this week, finally is this great company going to be recognised in an AIM world where huge indebted comapnies ĺike BMN and Hzm are faltering
DNA damage repair and CRUK seem to suggest perhaps PYC will still help or has bene helping more recently?
From SAR 28th March 2024 interims
Company will now focus its resources on the clinical development of SDC-1801.
SRA737 (cancer)
SRA737 is a clinical-stage oral, selective Checkpoint kinase 1 inhibitor that targets cancer cell replication and DNA damage repair mechanisms.
· After the period end, on 2 January 2024, Sareum announced the Company's co-development partner, the CRT Pioneer Fund ("CPF"), has entered into a development and commercialisation licence agreement for SRA737 with a private biopharma company based in the United States.
· Under the terms of Sareum's co-development agreements with CPF and Cancer Research Technology Ltd, Sareum is entitled to receive 27.5% of any income arising from this licensing of the SRA737 programme.
Thanks to Debull for the below
The candidate was CCT245737, which was renamed PNT737, then licensed out to Sierra by which time it was SRA737 https://www.edisongroup.com/research/sierra-oncology-returns-rights-to-sra737/31442/ Sierra bought out by GSK and then SRA737 rights were returned to SAR after GSK's purchase of Sierra. Or something along those lines!
Broken 2cd trend line ,next to a poss 50ema 1.80- to 1.90 area as first target ,volume determine break the 2.00 to 20 ema 2.40 area
https://invst.ly/14hzqf
In todays APTA RNS
Targeted delivery to specific cell populations is showing increasing use across the pharmaceutical sector, as it holds the potential for increased efficacy and reduced side effects from medications. Exemplar publicised partnerships for specifically targeted precision medicine developments include Ionis Pharmaceuticals Inc. licensing a single delivery vehicle from Bicycle Therapeutics Inc. for $45 million upfront, with additional milestone payments and royalties for each program developed under the collaboration; Partnering of Takeda Pharmaceutical with Peptidream Inc, with Peptidream Inc receiving up to $3.5 billion excluding royalty payments for delivery vehicles targeting the central nervous system. Both these deals demonstrate the urgent requirement and high values associated with developments and assets of this nature in the sector for successful targeting delivery vehicles.
Thanks Hopist
Not even £5 worth!
Anyone else finsing this?
Years ago we used Back Web Technology the ability (only when Licenced ) to communicate and input data direct onto 3rd Party Computers in this case Doctors Registered with The NHS to provide updates on alerts and advice for / services / diagnostic tools etc etc. Should the DOSEME RX app be approved and come to market it would be a route to all Doctors in the UK. This market alone is substantial. However I believe that PYC will probably need to "beef up" its sales team to promote it. That said they are in a partnership for the technology and and sales might well be directed by others. If successful the global market opportunity presents exponential growth.