Total Voting Rights

International Biotechnology Trust plc (the "Company")

Voting Rights and Capital

In accordance with the FCA's Disclosure and Transparency Rule 5.6.1R the Company would like to notify the market of the following:

At the close of business on the 30 June 2016, the Company had 42,042,663 Ordinary shares in issue, of which 4,130,000 were held in Treasury. Therefore the total number of voting rights in the Company was 37,912,663.

The above figure (37,912,663) may be used by Shareholders as the denominator for the calculations by which they will determine if they are required to notify their interest in, or a change to their interest in, the Company under the FCA's Disclosure and Transparency Rules.

Nariman Ghandhi

For and on behalf of

BNP Paribas Secretarial Services Limited

Company Secretary

Telephone: 020 7410 5971

30 JUNE 2016