Issue of Equity

Polar Capital Holdings Plc (the "Company")

Legal Entity Identifier: 549300OXX7YE1947B825

17 October 2017

Issue of Equity

The Company announces the allotment of 10,204 ordinary shares of 2.5 pence ("Ordinary Shares") each fully paid under its block listing facility (Sharesave Scheme). These shares have been allotted pursuant to the exercise of options by employees of the Company. These shares were issued for cash on 17 October 2017 and will rank pari passu in all respects with the Company's existing shares in issue.

Following the issue of the new shares the total number of Ordinary Shares in the Company with voting rights will be 91,950,702. The Company does not hold any Ordinary Shares in Treasury.

The above figure of 91,950,702 Ordinary Shares may be used by shareholders in the Company as the denominator for the calculations by which they will determine if they are required to notify their interest in, or a change to their interest in, the share capital of the Company under the Financial Conduct Authority's Disclosure and Transparency Rules.

For further information please contact:

Polar Capital

Neil Taylor (Company Secretary)

+44 (0)20 7227 2700

Canaccord Genuity - Nomad and Joint Broker

Simon Bridges (QE)

Andrew Buchanan

+44 (0)20 7523 8350