Exercise of Share Options by a Director

Exercise of Share Options by a Director

Hong Kong, Shanghai & Florham Park, NJ - Monday, August 7, 2023: HUTCHMED (China) Limited ("HUTCHMED" or the "Company") (Nasdaq/AIM: HCM, HKEX: 13) today announces that it has issued a total of 3,000,000 ordinary shares of US$0.10 each ("Ordinary Shares") following the exercise of share options by Dr Weiguo Su, Executive Director, Chief Executive Officer and Chief Scientific Officer, at an exercise price of GBP1.97 per Ordinary Share on August 7, 2023 (the "Exercise of Options").

Following the Exercise of Options, Dr Su is beneficially interested in 5,000,000 Ordinary Shares Note 1 and 632,505 American Depositary Shares ("ADSs") Note 2, representing 0.94% of the current issued share capital of the Company.

Notes:

1. 5,000,000 Ordinary Shares included (i) 3,000,000 Ordinary Shares currently held by Dr Su, and (ii) share options for 2,000,000 Ordinary Shares granted under Share Option Scheme

2. 632,505 ADSs included (i) 143,518 ADSs currently held by Dr Su, (ii) share options for 395,442 ADSs granted under Share Option Scheme and (iii) 93,545 ADSs as beneficiary of a trust under long term incentive plan.

The notification set out below is provided in accordance with the requirements of the EU Market Abuse Regulation.

About HUTCHMED

HUTCHMED (Nasdaq/AIM: HCM; HKEX: 13) is an innovative, commercial-stage, biopharmaceutical company. It is committed to the discovery and global development and commercialization of targeted therapies and immunotherapies for the treatment of cancer and immunological diseases. It has approximately 5,000 personnel across all its companies, at the center of which is a team of about 1,800 in oncology/immunology. Since inception it has focused on bringing cancer drug candidates from in-house discovery to patients around the world, with its first three oncology drugs now approved and marketed in China. For more information, please visit: www.hutch‑med.com or follow us on LinkedIn.

Forward-Looking Statements

This announcement contains forward-looking statements within the meaning of the "safe harbor" provisions of the U.S. Private Securities Litigation Reform Act of 1995. Forward-looking statements involve risks and uncertainties. Existing and prospective investors are cautioned not to place undue reliance on these forward-looking statements, which speak only as of the date hereof. For further discussion of these and other risks, see HUTCHMED's filings with the U.S. Securities and Exchange Commission, on AIM and on HKEX. HUTCHMED undertakes no obligation to update or revise the information contained in this announcement, whether as a result of new information, future events or circumstances or otherwise.

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