Blocklisting Interim Review

Name of applicant:

ASTRAZENECA PLC

Name of scheme:

ASTRAZENECA SHARE OPTION PLAN; ASTRAZENECA SAVINGS-RELATED SHARE OPTION PLAN; ASTRAZENECA ALL-EMPLOYEE SHARE PLAN; ASTRAZENECA PLC 2012 SAVINGS-RELATED SHARE OPTION SCHEME

Period of return:

From:

1 JUNE 2014

To:

30 NOVEMBER 2014

Balance of unallotted securities under scheme(s) from previous return:

6,135,870

Plus:  The amount by which the block scheme(s) has been increased since the date of the last return (if any increase has been applied for):

0

Less:  Number of securities issued/allotted under scheme(s) during period (see LR3.5.7G):

390,252

Equals:  Balance under scheme(s) not yet issued/allotted at end of period:

5,745,618

Name of contact:

MARTIN BENNETT

Telephone number of contact:

020 7604 8157