Appointment of Non-Executive Directors

INTERNATIONAL BIOTECHNOLOGY TRUST PLC (the Company)

Appointment of Non-Executive Directors

The Board of the Company is pleased to announce the appointment of Kate Cornish-Bowden and Patrick Magee as Non-Executive Directors of the Company with effect from Tuesday, 19 May 2020.

Kate worked for Morgan Stanley Investment Management for twelve years where she was a managing director, head of MSIM's global core equity business and head of the pharmaceuticals research team. Prior to joining Morgan Stanley, she worked for M&G Investment Management as a research analyst.

Kate is currently a non-executive director of Finsbury Growth & Income Trust plc, Schroder Oriental Income Fund Ltd, and a non-executive audit committee chair of CC Japan Income & Growth Trust plc and Calculus VCT plc. She has previously held directorships of Scancell Holdings plc and Arcis Biotechnology Limited.

Kate is a member of the Chartered Financial Analyst Institute (formerly AIIMR), holds an MBA and has completed the Financial Times Non-Executive Director Diploma.

Patrick is Chief Commercial Officer at the British Business Bank plc and is an executive director on the Bank's Board.

Before joining the British Business Bank in 2014, Patrick worked at the Shareholder Executive from June 2012 to October 2014, where his responsibilities included working on the establishment of the British Business Bank. Prior to joining the Shareholder Executive, Patrick was a managing director of corporate finance at JP Morgan Cazenove, having worked at the predecessor firms for almost 18 years.

In his career Patrick has advised on a broad range of M&A, Capital Markets and Corporate Broking assignments for a broad range of clients. Patrick also spent two years on secondment to the Panel for Takeovers and Mergers.

Patrick has an MBA from Georgetown University, Washington DC and an LLB from Queen's University Belfast. He is a member of the Investment Committee at Queen's University, Belfast

The following additional information is disclosed in accordance with Chapter 9 of the Financial Conduct Authority Listing Rules:

1. There are no details to be disclosed under Listing Rule 9.6.13R

2. As at today's date Kate Cornish-Bowden holds 8,000 Ordinary shares in the Company and Patrick Magee has no beneficial interest in the Ordinary shares of the Company.

As explained in the Company's Annual Report for the year ended 31 August 2019, John Aston intends to retire from the Board at the conclusion of the AGM to be held in December 2020 and it is expected that Dr Véronique Bouchet will retire shortly thereafter. An announcement as to who will succeed John as Chairman of the Company will be made later in the year.

For further information, please contact:

BNP Paribas Secretarial Services Limited

Company Secretary

020 7410 5971

19 MAY 2020