Appointment of Interim Chief Financial Officer

Itaconix plc ("Itaconix", the "Company" or the "Group")

Appointment of Interim Chief Financial Officer

Itaconix announces today the appointment of Michael Norris as interim Chief Financial Officer with effect from 1 September 2018. Given the previously announced restructuring of the business, Robin Cridland will retire from the Board and leave the Company with effect from 31 August 2018 and will be treated as a good leaver. Michael will commence with the Company with immediate effect to facilitate an appropriate handover period. Michael will not be a director of the Company.

Michael Norris is an experienced private and public company CFO with over 20 years' board level experience. Michael has a strong entrepreneurial background and is a Fellow of the Chartered Institute of Management Accountants. Michael has been appointed on an interim basis while the Board undertakes a process to find a permanent successor.

Robin Cridland has been CFO of the Company since 2008 and co-led the flotation on the AIM Market in July 2012. As well as fulfilling the duties of a public company CFO, he has played a significant role in the commercial development and financing of the Company through his 10-year tenure. He is now looking forward to working on other projects, including expanding his non-executive portfolio.

John Shaw, Chief Executive Officer commented: "The Board thanks Robin for his dedicated service to the Company over many years and wishes him well in his new endeavours. We are pleased to welcome Michael to Itaconix."

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