ValiRx Regulatory News (VAL)

1 May 2014

ValiRx Plc

("ValiRx" or the "Company")

New Japanese Patent Grant for ValiRx's

Cancer Screening Test Biomarker

ValiRx Plc (AIM: VAL), a life science company with a focus on cancer diagnostics and therapeutics for personalised medicine, is pleased to announce that NAV3, a cancer screening test gene biomarker  which is one of the five patent family assets that ValiRx's subsidiary, ValiFinn Oy, acquired in 2012, has recently received patent approval by the Japanese patent office ("JPO"). 

The granting of this latest patent to the Company means that ValiRx now has biomarker granted patent protection in Japan, Europe and Australia and patents pending in the US and other territories, alongside granted and patents pending for its therapeutic technologies across Europe, the US, Canada and Australia.

The use of biomarkers with oncology therapeutics is one of the fastest growing areas of cancer research, as not only can the biomarkers identify patients who are more likely to respond to a particular drug therapy, but they can also indicate tumour progression.

The NAV3 gene biomarker can be used in the following ways to:

· detect pre-malignant cells at the stage where tumour development is only about to start

· form a highly sensitive and specific test for finding cancer cells in tissue or samples

· enable the tracking of only a few malignant cells

· examine various samples and biopsy types

In cancer diagnostics the detection of malignant cells as early as possible is a key challenge. Early detection can often have a significant impact on the future survival of cancer patients. The current diagnostic methods for cancer rely mainly on the microscopic analysis of cells in biopsies. However, at the early stage of cancer and before morphological changes have developed, such malignant cell detection is and remains difficult.

The test is based on the detection of specific changes in the NAV3 gene and the system of tests can be applied to a range of cancers including colon cancer, breast cancer, lung cancer, lymphomas and cancers of neurological origin. The clinical relevance of NAV3 is being further investigated in other solid tumours.

Dr Satu Vainikka, CEO, commented: "The granting of this latest patent by the JPO shortly after our European patent grant, not only further extends our global geographic patent coverage, but continues to endorse the Board's decision to establish ValiFinn and our Finnish biomarkers business, in a increasingly fast growing marketplace".

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Notes for Editors 

ValiRx Plc

ValiRx Plc is a biopharmaceutical company developing novel technologies and products in oncology

therapeutics and diagnostics. The product focus is in the epigenomic analysis and treatment of cancer, but the technologies can be applied to other fields as well, such as neurology and inflammatory diseases.

The Company listed on AIM in October 2006 and is creating a portfolio of innovative products through investment in specific development projects. It actively manages projects within this portfolio as a trading company and is not an investment vehicle. The ValiRx business model spreads the risks of life science technology developments by minimising financial exposure and running a set of projects to defined commercial endpoints. This maximises returns to shareholders by adding value at the earlier stages where value increases per investment unit are the greatest.

The Company operates through the following divisional companies:

1. ValiFinn is the biomarkers and diagnostic development division

2. ValiPharma is the therapeutics division with two embedded technologies primarily directed at

the treatment of cancers.