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Form 8.3 - Shire Plc

21 Dec 2018 10:41

RNS Number : 2768L

Societe Generale SA

21 December 2018

FORM 8.3

PUBLIC OPENING POSITION DISCLOSURE/DEALING DISCLOSURE BY

A PERSON WITH INTERESTS IN RELEVANT SECURITIES REPRESENTING 1% OR MORE

Rule 8.3 of the Takeover Code (the "Code")

1. KEY INFORMATION

(a) Full name of discloser:	Société Générale S.A.
(b) Owner or controller of interests and short positions disclosed, if different from 1(a): The naming of nominee or vehicle companies is insufficient. For a trust, the trustee(s), settlor and beneficiaries must be named.
(c) Name of offeror/offeree in relation to whose relevant securities this form relates: Use a separate form for each offeror/offeree	Shire Plc
(d) If an exempt fund manager connected with an offeror/offeree, state this and specify identity of offeror/offeree:
(e) Date position held/dealing undertaken: For an opening position disclosure, state the latest practicable date prior to the disclosure	20/12/2018
(f) In addition to the company in 1(c) above, is the discloser making disclosures in respect of any other party to the offer? If it is a cash offer or possible cash offer, state "N/A"	YES: Takeda Pharmaceutical Company Limited

2. POSITIONS OF THE PERSON MAKING THE DISCLOSURE

If there are positions or rights to subscribe to disclose in more than one class of relevant securities of the offeror or offeree named in 1(c), copy table 2(a) or (b) (as appropriate) for each additional class of relevant security.

(a) Interests and short positions in the relevant securities of the offeror or offeree to which the disclosure relates following the dealing (if any)

Class of relevant security:	Ordinary shares: 17,938,409 Shares Interests and 13,050,051 short position ADR (referencing the ordinary): 462,045 equivalent Shares interests and 52,485 equivalent Shares as short position Where (1 ADR = 3 ordinary shares)
	Interests		Short positions
	Number	%	Number	%
(1) Relevant securities owned and/or controlled:	18,400,454	2.01	13,102,536	1.43
(2) Cash-settled derivatives:	13,646,886	1.49	17,212,257	1.88
(3) Stock-settled derivatives (including options) and agreements to purchase/sell:	400,100	0.04	364,400	0.04
TOTAL:	32,447,440	3.54	30,679,193	3.35

All interests and all short positions should be disclosed.

Details of any open stock-settled derivative positions (including traded options), or agreements to purchase or sell relevant securities, should be given on a Supplemental Form 8 (Open Positions).

(b) Rights to subscribe for new securities (including directors' and other employee options)

Class of relevant security in relation to which subscription right exists:
Details, including nature of the rights concerned and relevant percentages:

3. DEALINGS (IF ANY) BY THE PERSON MAKING THE DISCLOSURE

Where there have been dealings in more than one class of relevant securities of the offeror or offeree named in 1(c), copy table 3(a), (b), (c) or (d) (as appropriate) for each additional class of relevant security dealt in.

The currency of all prices and other monetary amounts should be stated.

(a) Purchases and sales

Class of relevant security	Purchase/sale	Number of securities	Price per unit GBP
Ordinary	Purchase	53	45.275
Ordinary	Purchase	55	45.275
Ordinary	Purchase	153	44.91
Ordinary	Purchase	3,321	44.91
Ordinary	Purchase	9,411	44.91
Ordinary	Purchase	3,352	44.91
Ordinary	Purchase	163	44.91
Ordinary	Purchase	416	44.91
Ordinary	Purchase	12,763	44.91
Ordinary	Purchase	122	45.23
Ordinary	Purchase	104	45.65
Ordinary	Purchase	92	45.215
Ordinary	Purchase	70	45.24
Ordinary	Purchase	37	45.28
Ordinary	Purchase	257	45.285
Ordinary	Purchase	129	45.47
Ordinary	Purchase	122	45.3
Ordinary	Purchase	88	45.68
Ordinary	Purchase	76	45.23
Ordinary	Purchase	53	45.22
Ordinary	Purchase	129	45.205
Ordinary	Purchase	301	45.215
Ordinary	Purchase	55	45.225
Ordinary	Purchase	103	45.215
Ordinary	Purchase	524	45.295
Ordinary	Purchase	124	45.295
Ordinary	Purchase	84	45.295
Ordinary	Purchase	70	45.23
Ordinary	Purchase	71	45.265
Ordinary	Purchase	136	45.3
Ordinary	Purchase	152	45.3
Ordinary	Purchase	93	45.355
Ordinary	Purchase	81	45.355
Ordinary	Purchase	109	45.365
Ordinary	Purchase	73	45.24
Ordinary	Purchase	21	45.51
Ordinary	Purchase	100	45.51
Ordinary	Purchase	50	45.51
Ordinary	Purchase	214	45.51
Ordinary	Purchase	208	45.275
Ordinary	Purchase	290	45.36
Ordinary	Purchase	124	45.24
Ordinary	Purchase	125	45.28
Ordinary	Purchase	44	45.28
Ordinary	Purchase	123	45.715
Ordinary	Purchase	61	45.51
Ordinary	Purchase	20	45.715
Ordinary	Purchase	208	45.345
Ordinary	Purchase	56	45.47
Ordinary	Purchase	176	45.28
Ordinary	Purchase	276	45.47
Ordinary	Purchase	134	45.205
Ordinary	Purchase	45	45.295
Ordinary	Purchase	121	45.49
Ordinary	Purchase	85	45.29
Ordinary	Purchase	101	45.275
Ordinary	Purchase	110	45.295
Ordinary	Purchase	178	45.305
Ordinary	Purchase	72	45.305
Ordinary	Purchase	26	45.305
Ordinary	Purchase	86	45.21
Ordinary	Purchase	335	45.285
Ordinary	Purchase	12	45.21
Ordinary	Purchase	490	45.585
Ordinary	Purchase	43	45.305
Ordinary	Purchase	123	45.305
Ordinary	Purchase	49	45.43
Ordinary	Purchase	289	45.32
Ordinary	Purchase	125	45.515
Ordinary	Purchase	125	45.515
Ordinary	Purchase	50	45.25
Ordinary	Purchase	125	45.25
Ordinary	Purchase	196	45.24
Ordinary	Purchase	103	45.44
Ordinary	Purchase	42	45.315
Ordinary	Purchase	136	45.315
Ordinary	Purchase	263	45.315
Ordinary	Purchase	160	45.315
Ordinary	Purchase	103	45.315
Ordinary	Purchase	63	45.23
Ordinary	Purchase	104	45.31
Ordinary	Purchase	222	45.275
Ordinary	Purchase	124	45.275
Ordinary	Purchase	8	45.275
Ordinary	Purchase	110	45.625
Ordinary	Purchase	250	45.625
Ordinary	Purchase	75	45.4
Ordinary	Purchase	70	45.33
Ordinary	Purchase	252	45.32
Ordinary	Purchase	130	45.33
Ordinary	Purchase	9	45.33
Ordinary	Purchase	41	45.265
Ordinary	Purchase	9	45.265
Ordinary	Purchase	125	45.53
Ordinary	Purchase	160	45.53
Ordinary	Purchase	58	45.315
Ordinary	Purchase	98	45.23
Ordinary	Purchase	51	45.295
Ordinary	Purchase	111	45.295
Ordinary	Purchase	329	45.21
Ordinary	Purchase	87	45.32
Ordinary	Purchase	75	45.135
Ordinary	Purchase	51	45.22
Ordinary	Purchase	76	45.385
Ordinary	Purchase	174	45.215
Ordinary	Purchase	144	45.22
Ordinary	Purchase	169	45.505
Ordinary	Purchase	108	45.22
Ordinary	Purchase	168	45.22
Ordinary	Purchase	202	45.22
Ordinary	Purchase	62	45.315
Ordinary	Purchase	63	45.265
Ordinary	Purchase	47	45.225
Ordinary	Purchase	100	45.225
Ordinary	Purchase	77	45.225
Ordinary	Purchase	122	45.225
Ordinary	Purchase	86	45.265
Ordinary	Purchase	90	45.3
Ordinary	Purchase	34	45.615
Ordinary	Purchase	97	45.415
Ordinary	Purchase	49	45.62
Ordinary	Purchase	75	45.295
Ordinary	Purchase	75	45.295
Ordinary	Purchase	103	45.295
Ordinary	Purchase	54	45.335
Ordinary	Purchase	54	45.265
Ordinary	Purchase	10	45.265
Ordinary	Purchase	438	45.265
Ordinary	Purchase	33	45.25
Ordinary	Purchase	107	45.32
Ordinary	Purchase	410	45.3
Ordinary	Purchase	69	45.685
Ordinary	Purchase	131	45.685
Ordinary	Purchase	37	45.525
Ordinary	Purchase	43	45.515
Ordinary	Purchase	51	45.565
Ordinary	Purchase	7	45.595
Ordinary	Purchase	65	45.595
Ordinary	Purchase	15	45.275
Ordinary	Purchase	607	44.91
Ordinary	Purchase	260	45.585
Ordinary	Purchase	258	45.595
Ordinary	Purchase	143	45.22
Ordinary	Purchase	206	45.51
Ordinary	Purchase	168	45.27
Ordinary	Purchase	138	45.28
Ordinary	Purchase	80	45.575
Ordinary	Purchase	178	45.575
Ordinary	Purchase	250	45.57
Ordinary	Purchase	8	45.57
Ordinary	Purchase	153	45.26
Ordinary	Purchase	150	45.26
Ordinary	Purchase	220	45.26
Ordinary	Purchase	264	45.245
Ordinary	Purchase	260	45.27
Ordinary	Purchase	92	45.27
Ordinary	Purchase	262	45.28
Ordinary	Purchase	323	45.51
Ordinary	Purchase	55	45.51
Ordinary	Purchase	135	45.28
Ordinary	Purchase	260	45.275
Ordinary	Purchase	5	45.28
Ordinary	Purchase	260	45.275
Ordinary	Purchase	190	45.285
Ordinary	Purchase	78	45.245
Ordinary	Purchase	260	45.25
Ordinary	Purchase	70	45.285
Ordinary	Purchase	159	45.295
Ordinary	Purchase	163	45.565
Ordinary	Purchase	44	45.565
Ordinary	Purchase	82	45.645
Ordinary	Purchase	132	45.29
Ordinary	Purchase	296	45.295
Ordinary	Purchase	262	45.24
Ordinary	Purchase	58	45.575
Ordinary	Purchase	200	45.575
Ordinary	Purchase	96	45.58
Ordinary	Purchase	162	45.58
Ordinary	Purchase	212	45.645
Ordinary	Purchase	134	45.525
Ordinary	Purchase	257	45.69
Ordinary	Purchase	257	45.695
Ordinary	Purchase	257	45.725
Ordinary	Purchase	359	45.24
Ordinary	Purchase	512	45.24
Ordinary	Purchase	5,596	44.91
Ordinary	Purchase	90	45.625
Ordinary	Purchase	272	45.625
Ordinary	Purchase	4,668	44.91
Ordinary	Purchase	180	45.275
Ordinary	Purchase	129	45.275
Ordinary	Purchase	140	45.72
Ordinary	Purchase	117	45.72
Ordinary	Purchase	257	45.73
Ordinary	Purchase	138	45.625
Ordinary	Purchase	159	45.625
Ordinary	Purchase	251	45.595
Ordinary	Purchase	585	45.625
Ordinary	Purchase	227	45.625
Ordinary	Purchase	260	45.245
Ordinary	Purchase	113	45.72
Ordinary	Purchase	258	45.65
Ordinary	Purchase	257	45.67
Ordinary	Purchase	128	45.4
Ordinary	Purchase	250	45.655
Ordinary	Purchase	46	45.645
Ordinary	Purchase	137	45.64
Ordinary	Purchase	258	45.495
Ordinary	Purchase	172	45.49
Ordinary	Purchase	88	45.49
Ordinary	Purchase	263	45.48
Ordinary	Purchase	121	45.64
Ordinary	Purchase	257	45.725
Ordinary	Purchase	146	45.72
Ordinary	Purchase	193	45.595
Ordinary	Purchase	222	45.69
Ordinary	Purchase	647	45.7
Ordinary	Purchase	258	45.59
Ordinary	Purchase	257	45.68
Ordinary	Purchase	257	45.675
Ordinary	Purchase	103	45.21
Ordinary	Purchase	258	45.625
Ordinary	Purchase	6	45.21
Ordinary	Purchase	4	45.57
Ordinary	Purchase	254	45.57
Ordinary	Purchase	79	45.57
Ordinary	Purchase	179	45.57
Ordinary	Purchase	28	45.65
Ordinary	Purchase	258	45.565
Ordinary	Purchase	176	45.645
Ordinary	Purchase	236	45.22
Ordinary	Purchase	258	45.55
Ordinary	Purchase	100	45.22
Ordinary	Purchase	272	45.22
Ordinary	Purchase	258	45.59
Ordinary	Purchase	261	45.265
Ordinary	Purchase	205	45.55
Ordinary	Purchase	53	45.55
Ordinary	Purchase	245	45.5
Ordinary	Purchase	13	45.5
Ordinary	Purchase	230	45.295
Ordinary	Purchase	230	45.65
Ordinary	Purchase	260	45.305
Ordinary	Purchase	163	45.295
Ordinary	Purchase	258	45.575
Ordinary	Purchase	166	45.3
Ordinary	Purchase	94	45.3
Ordinary	Purchase	111	45.265
Ordinary	Purchase	137	45.265
Ordinary	Purchase	174	45.265
Ordinary	Purchase	230	45.265
Ordinary	Purchase	129	45.265
Ordinary	Purchase	216	45.545
Ordinary	Purchase	42	45.545
Ordinary	Purchase	260	45.22
Ordinary	Purchase	12	45.27
Ordinary	Purchase	378	45.25
Ordinary	Purchase	360	45.245
Ordinary	Purchase	55	45.24
Ordinary	Purchase	323	45.24
Ordinary	Purchase	3	45.2
Ordinary	Purchase	1	45.2
Ordinary	Purchase	5	45.2
Ordinary	Purchase	91	45.2
Ordinary	Purchase	38	45.285
Ordinary	Purchase	9,711	44.91
Ordinary	Purchase	85	45.33
Ordinary	Purchase	21	45.33
Ordinary	Purchase	134	45.365
Ordinary	Purchase	106	45.225
Ordinary	Purchase	61	45.22
Ordinary	Purchase	150	45.295
Ordinary	Purchase	197	45.305
Ordinary	Purchase	46	45.23
Ordinary	Purchase	104	45.325
Ordinary	Purchase	121	45.315
Ordinary	Purchase	40	45.315
Ordinary	Purchase	161	45.31
Ordinary	Purchase	36	45.31
Ordinary	Purchase	125	45.295
Ordinary	Purchase	46	45.245
Ordinary	Purchase	64	45.23
Ordinary	Purchase	64	45.12
Ordinary	Purchase	62	45.235
Ordinary	Purchase	90	45.27
Ordinary	Purchase	64	45.27
Ordinary	Purchase	53	45.26
Ordinary	Purchase	51	45.23
Ordinary	Purchase	48	45.225
Ordinary	Purchase	58	45.235
Ordinary	Purchase	97	45.295
Ordinary	Purchase	83	45.225
Ordinary	Purchase	67	45.265
Ordinary	Purchase	7	45.655
Ordinary	Purchase	57	45.325
Ordinary	Purchase	51	45.255
Ordinary	Purchase	55	45.235
Ordinary	Purchase	49	45.225
Ordinary	Purchase	55	45.235
Ordinary	Purchase	216	45.24
Ordinary	Purchase	82	45.31
Ordinary	Purchase	29	45.335
Ordinary	Purchase	110	45.335
Ordinary	Purchase	122	45.22
Ordinary	Purchase	38	45.51
Ordinary	Purchase	41	45.24
Ordinary	Purchase	90	45.28
Ordinary	Purchase	89	45.51
Ordinary	Purchase	50	45.345
Ordinary	Purchase	88	45.345
Ordinary	Purchase	59	45.24
Ordinary	Purchase	108	45.29
Ordinary	Purchase	199	45.295
Ordinary	Purchase	20	45.29
Ordinary	Purchase	114	45.29
Ordinary	Purchase	39	45.145
Ordinary	Purchase	34	45.255
Ordinary	Purchase	20	45.255
Ordinary	Purchase	69	45.3
Ordinary	Purchase	239	45.525
Ordinary	Purchase	94	45.21
Ordinary	Purchase	166	45.3
Ordinary	Purchase	173	45.29
Ordinary	Purchase	53	45.41
Ordinary	Purchase	76	45.28
Ordinary	Purchase	13	45.515
Ordinary	Purchase	21	45.325
Ordinary	Purchase	30	45.325
Ordinary	Purchase	41	45.32
Ordinary	Purchase	84	45.32
Ordinary	Purchase	100	45.32
Ordinary	Purchase	124	45.32
Ordinary	Purchase	97	45.33
Ordinary	Purchase	107	45.31
Ordinary	Purchase	122	45.44
Ordinary	Purchase	101	45.21
Ordinary	Purchase	50	45.145
Ordinary	Purchase	120	45.355
Ordinary	Purchase	53	45.355
Ordinary	Purchase	109	45.4
Ordinary	Purchase	252	45.32
Ordinary	Purchase	212	45.33
Ordinary	Purchase	53	45.315
Ordinary	Purchase	86	45.15
Ordinary	Purchase	60	45.31
Ordinary	Purchase	61	45.22
Ordinary	Purchase	13	45.32
Ordinary	Purchase	122	45.49
Ordinary	Purchase	4	45.235
Ordinary	Purchase	81	45.15
Ordinary	Purchase	50	45.28
Ordinary	Purchase	237	45.22
Ordinary	Purchase	98	45.22
Ordinary	Purchase	30	45.22
Ordinary	Purchase	104	45.22
Ordinary	Purchase	64	45.505
Ordinary	Purchase	128	45.22
Ordinary	Purchase	68	45.315
Ordinary	Purchase	51	45.285
Ordinary	Purchase	91	45.27
Ordinary	Purchase	116	45.265
Ordinary	Purchase	86	45.265
Ordinary	Purchase	17	45.615
Ordinary	Purchase	91	45.615
Ordinary	Purchase	60	45.335
Ordinary	Purchase	18	45.225
Ordinary	Purchase	52	45.225
Ordinary	Purchase	100	45.265
Ordinary	Purchase	174	45.265
Ordinary	Purchase	51	45.27
Ordinary	Purchase	98	45.27
Ordinary	Purchase	93	45.32
Ordinary	Purchase	19	45.3
Ordinary	Purchase	97	45.3
Ordinary	Purchase	11	45.295
Ordinary	Purchase	224	45.295
Ordinary	Purchase	111	45.295
Ordinary	Purchase	97	45.135
Ordinary	Purchase	51	45.145
Ordinary	Purchase	59	45.245
Ordinary	Purchase	29	45.365
Ordinary	Purchase	4	45.2
Ordinary	Purchase	200,000	46.02219248
Ordinary	Purchase	600,000	45.605
Ordinary	Purchase	10,000	45.675432
Ordinary	Purchase	100,000	45.49415704
Ordinary	Purchase	100,000	45.49415704
Ordinary	Purchase	400,000	45.84329747
Ordinary	Purchase	59	45.305
Ordinary	Purchase	67	45.265
Ordinary	Purchase	56	45.238212
Ordinary	Purchase	867	45.238212
Class of relevant security	Purchase/sale	Number of securities	Price per unit USD
ADR	Purchase	405	171.21
ADR	Purchase	300	170.48
ADR	Purchase	30	170.994
ADR	Purchase	99	171.81
ADR	Purchase	3,657	171.216341
ADR	Purchase	1,275	171.21
ADR	Purchase	21,759	171.408933
ADR	Purchase	9,900	172.2
ADR	Purchase	20,100	172.2
ADR	Purchase	6,636	171.21
Class of relevant security	Purchase/sale	Number of securities	Price per unit GBP
Ordinary	Sale	368	45.415
Ordinary	Sale	80	45.49
Ordinary	Sale	60	45.49
Ordinary	Sale	49	45.49
Ordinary	Sale	51	45.205
Ordinary	Sale	81	45.205
Ordinary	Sale	73	45.655
Ordinary	Sale	79	45.555
Ordinary	Sale	73	45.665
Ordinary	Sale	138	45.665
Ordinary	Sale	201	45.665
Ordinary	Sale	107	45.665
Ordinary	Sale	69	45.66
Ordinary	Sale	270	45.53
Ordinary	Sale	69	45.645
Ordinary	Sale	72	45.665
Ordinary	Sale	7	45.28
Ordinary	Sale	189	45.28
Ordinary	Sale	125	45.28
Ordinary	Sale	125	45.495
Ordinary	Sale	57	45.495
Ordinary	Sale	110	45.585
Ordinary	Sale	200	45.5
Ordinary	Sale	139	45.595
Ordinary	Sale	200	45.5
Ordinary	Sale	152	45.5
Ordinary	Sale	261	45.5
Ordinary	Sale	56	45.5
Ordinary	Sale	150	45.62
Ordinary	Sale	2	45.62
Ordinary	Sale	351	45.54
Ordinary	Sale	231	45.54
Ordinary	Sale	52	45.64
Ordinary	Sale	158	45.64
Ordinary	Sale	218	45.295
Ordinary	Sale	45	45.295
Ordinary	Sale	246	45.295
Ordinary	Sale	170	45.295
Ordinary	Sale	365	45.665
Ordinary	Sale	101	45.295
Ordinary	Sale	3	45.465
Ordinary	Sale	37	45.255
Ordinary	Sale	86	45.22
Ordinary	Sale	85	45.21
Ordinary	Sale	14	45.205
Ordinary	Sale	93	45.275
Ordinary	Sale	260	45.245
Ordinary	Sale	260	45.27
Ordinary	Sale	81	45.33
Ordinary	Sale	179	45.33
Ordinary	Sale	238	45.65
Ordinary	Sale	203	45.55
Ordinary	Sale	55	45.55
Ordinary	Sale	260	45.295
Ordinary	Sale	260	45.28
Ordinary	Sale	257	45.665
Ordinary	Sale	582	45.65
Ordinary	Sale	258	45.5
Ordinary	Sale	225	45.655
Ordinary	Sale	358	45.525
Ordinary	Sale	354	45.53
Ordinary	Sale	274	45.475
Ordinary	Sale	104	45.475
Ordinary	Sale	277	45.46
Ordinary	Sale	261	45.465
Ordinary	Sale	50	45.655
Ordinary	Sale	181	45.54
Ordinary	Sale	1,168	45.51
Ordinary	Sale	272	45.53
Ordinary	Sale	258	45.535
Ordinary	Sale	375	45.62
Ordinary	Sale	258	45.65
Ordinary	Sale	258	45.515
Ordinary	Sale	264	45.52
Ordinary	Sale	260	45.33
Ordinary	Sale	177	45.54
Ordinary	Sale	900	45.6
Ordinary	Sale	130	45.66
Ordinary	Sale	336	45.475
Ordinary	Sale	258	45.545
Ordinary	Sale	259	45.495
Ordinary	Sale	258	45.59
Ordinary	Sale	257	45.67
Ordinary	Sale	259	45.415
Ordinary	Sale	264	45.49
Ordinary	Sale	200	45.49
Ordinary	Sale	285	45.56
Ordinary	Sale	303	45.565
Ordinary	Sale	296	45.575
Ordinary	Sale	305	45.57
Ordinary	Sale	200	45.5
Ordinary	Sale	367	45.505
Ordinary	Sale	385	45.51
Ordinary	Sale	259	45.405
Ordinary	Sale	261	45.41
Ordinary	Sale	260	45.385
Ordinary	Sale	262	45.39
Ordinary	Sale	260	45.24
Ordinary	Sale	200	45.5
Ordinary	Sale	524	45.54
Ordinary	Sale	258	45.545
Ordinary	Sale	260	45.55
Ordinary	Sale	258	45.545
Ordinary	Sale	258	45.65
Ordinary	Sale	258	45.645
Ordinary	Sale	20	45.65
Ordinary	Sale	17	45.55
Ordinary	Sale	241	45.55
Ordinary	Sale	197	45.35
Ordinary	Sale	37	45.35
Ordinary	Sale	51	45.58
Ordinary	Sale	322	45.58
Ordinary	Sale	66	45.58
Ordinary	Sale	485	45.58
Ordinary	Sale	291	45.545
Ordinary	Sale	260	45.23
Ordinary	Sale	9	45.35
Ordinary	Sale	260	45.335
Ordinary	Sale	260	45.33
Ordinary	Sale	258	45.545
Ordinary	Sale	197	45.2
Ordinary	Sale	306	45.555
Ordinary	Sale	258	45.495
Ordinary	Sale	256	45.465
Ordinary	Sale	322	45.545
Ordinary	Sale	10	45.405
Ordinary	Sale	101	45.275
Ordinary	Sale	24	45.31
Ordinary	Sale	101	45.2
Ordinary	Sale	101	45.26
Ordinary	Sale	101	45.28
Ordinary	Sale	101	45.285
Ordinary	Sale	103	45.29
Ordinary	Sale	101	45.125
Ordinary	Sale	100	45.3
Ordinary	Sale	1	45.285
Ordinary	Sale	100	45.285
Ordinary	Sale	19	45.285
Ordinary	Sale	101	45.13
Ordinary	Sale	4	45.275
Ordinary	Sale	5	45.51
Ordinary	Sale	82	45.285
Ordinary	Sale	101	45.205
Ordinary	Sale	99	45.265
Ordinary	Sale	2	45.265
Ordinary	Sale	103	45.405
Ordinary	Sale	67	45.135
Ordinary	Sale	101	45.29
Ordinary	Sale	101	45.25
Ordinary	Sale	77	45.31
Ordinary	Sale	101	45.215
Ordinary	Sale	188	45.225
Ordinary	Sale	101	45.145
Ordinary	Sale	55	45.205
Ordinary	Sale	101	45.28
Ordinary	Sale	101	45.125
Ordinary	Sale	34	45.135
Ordinary	Sale	101	45.29
Ordinary	Sale	101	45.3
Ordinary	Sale	101	45.325
Ordinary	Sale	100	45.305
Ordinary	Sale	101	45.415
Ordinary	Sale	1	45.305
Ordinary	Sale	100	45.275
Ordinary	Sale	41	45.235
Ordinary	Sale	101	45.21
Ordinary	Sale	49	44.91
Ordinary	Sale	49	44.91
Ordinary	Sale	43	44.91
Ordinary	Sale	45	44.91
Ordinary	Sale	46	44.91
Ordinary	Sale	49	44.91
Ordinary	Sale	49	44.91
Ordinary	Sale	46	44.91
Ordinary	Sale	101	45.285
Ordinary	Sale	103	45.23
Ordinary	Sale	103	45.32
Ordinary	Sale	103	45.365
Ordinary	Sale	11	45.405
Ordinary	Sale	101	45.285
Ordinary	Sale	101	45.14
Ordinary	Sale	101	45.29
Ordinary	Sale	103	45.205
Ordinary	Sale	103	45.285
Ordinary	Sale	103	45.27
Ordinary	Sale	101	45.31
Ordinary	Sale	101	45.285
Ordinary	Sale	103	45.335
Ordinary	Sale	50	45.22
Ordinary	Sale	101	45.275
Ordinary	Sale	101	45.17
Ordinary	Sale	101	45.29
Ordinary	Sale	103	45.3
Ordinary	Sale	101	45.275
Ordinary	Sale	101	45.275
Ordinary	Sale	103	45.22
Ordinary	Sale	103	45.23
Ordinary	Sale	101	45.255
Ordinary	Sale	101	45.32
Ordinary	Sale	101	45.295
Ordinary	Sale	78	45.305
Ordinary	Sale	23	45.31
Ordinary	Sale	103	45.31
Ordinary	Sale	103	45.34
Ordinary	Sale	101	45.3
Ordinary	Sale	101	45.195
Ordinary	Sale	103	45.315
Ordinary	Sale	101	45.16
Ordinary	Sale	103	45.245
Ordinary	Sale	101	45.125
Ordinary	Sale	103	45.225
Ordinary	Sale	103	45.33
Ordinary	Sale	87	45.26
Ordinary	Sale	16	45.26
Ordinary	Sale	103	45.305
Ordinary	Sale	101	45.14
Ordinary	Sale	101	45.315
Ordinary	Sale	24	45.18
Ordinary	Sale	77	45.18
Ordinary	Sale	101	45.3
Ordinary	Sale	101	45.265
Ordinary	Sale	22	45.26
Ordinary	Sale	103	45.21
Ordinary	Sale	103	45.27
Ordinary	Sale	91	45.29
Ordinary	Sale	101	45.185
Ordinary	Sale	101	45.27
Ordinary	Sale	101	45.255
Ordinary	Sale	103	45.515
Ordinary	Sale	103	45.3
Ordinary	Sale	103	45.275
Ordinary	Sale	103	45.245
Ordinary	Sale	103	45.35
Ordinary	Sale	103	45.36
Ordinary	Sale	103	45.45
Ordinary	Sale	2	45.14
Ordinary	Sale	101	45.28
Ordinary	Sale	99	45.135
Ordinary	Sale	103	45.215
Ordinary	Sale	103	45.205
Ordinary	Sale	101	45.135
Ordinary	Sale	103	45.32
Ordinary	Sale	103	45.29
Ordinary	Sale	101	45.295
Ordinary	Sale	101	45.29
Ordinary	Sale	101	45.25
Ordinary	Sale	103	45.185
Ordinary	Sale	103	45.275
Ordinary	Sale	7	45.255
Ordinary	Sale	101	45.27
Ordinary	Sale	96	45.255
Ordinary	Sale	103	45.36
Ordinary	Sale	103	45.28
Ordinary	Sale	103	45.27
Ordinary	Sale	101	45.12
Ordinary	Sale	71	45.145
Ordinary	Sale	103	45.27
Ordinary	Sale	101	45.29
Ordinary	Sale	12	45.29
Ordinary	Sale	101	45.13
Ordinary	Sale	103	45.18
Ordinary	Sale	103	45.42
Ordinary	Sale	101	45.295
Ordinary	Sale	101	45.135
Ordinary	Sale	20	45.155
Ordinary	Sale	101	45.315
Ordinary	Sale	3	45.29
Ordinary	Sale	96	45.29
Ordinary	Sale	2	45.285
Ordinary	Sale	12	45.155
Ordinary	Sale	101	45.16
Ordinary	Sale	103	45.275
Ordinary	Sale	103	45.21
Ordinary	Sale	31	45.5
Ordinary	Sale	72	45.5
Ordinary	Sale	103	45.505
Ordinary	Sale	103	45.29
Ordinary	Sale	103	45.29
Ordinary	Sale	103	45.22
Ordinary	Sale	53	45.22
Ordinary	Sale	101	45.265
Ordinary	Sale	101	45.28
Ordinary	Sale	103	45.205
Ordinary	Sale	103	45.17
Ordinary	Sale	103	45.32
Ordinary	Sale	103	45.41
Ordinary	Sale	103	45.36
Ordinary	Sale	101	45.16
Ordinary	Sale	103	45.305
Ordinary	Sale	101	45.195
Ordinary	Sale	103	45.3
Ordinary	Sale	103	45.285
Ordinary	Sale	101	45.275
Ordinary	Sale	44	45.15
Ordinary	Sale	57	45.15
Ordinary	Sale	103	45.27
Ordinary	Sale	80	45.27
Ordinary	Sale	103	45.205
Ordinary	Sale	112	45.295
Ordinary	Sale	34	45.3
Ordinary	Sale	103	45.235
Ordinary	Sale	85	45.21
Ordinary	Sale	103	45.42
Ordinary	Sale	103	45.3
Ordinary	Sale	101	45.175
Ordinary	Sale	101	45.17
Ordinary	Sale	103	45.28
Ordinary	Sale	101	45.26
Ordinary	Sale	103	45.24
Ordinary	Sale	103	45.44
Ordinary	Sale	103	45.305
Ordinary	Sale	25	45.275
Ordinary	Sale	78	45.275
Ordinary	Sale	5	45.21
Ordinary	Sale	103	45.275
Ordinary	Sale	98	45.21
Ordinary	Sale	103	45.405
Ordinary	Sale	103	45.3
Ordinary	Sale	101	45.13
Ordinary	Sale	5	45.275
Ordinary	Sale	5	45.515
Ordinary	Sale	103	45.22
Ordinary	Sale	101	45.175
Ordinary	Sale	101	45.145
Ordinary	Sale	103	45.2
Ordinary	Sale	103	45.315
Ordinary	Sale	103	45.29
Ordinary	Sale	103	45.255
Ordinary	Sale	103	45.325
Ordinary	Sale	103	45.36
Ordinary	Sale	103	45.205
Ordinary	Sale	103	45.335
Ordinary	Sale	101	45.28
Ordinary	Sale	101	45.215
Ordinary	Sale	101	45.125
Ordinary	Sale	75	45.285
Ordinary	Sale	26	45.285
Ordinary	Sale	103	45.4
Ordinary	Sale	101	45.15
Ordinary	Sale	103	45.435
Ordinary	Sale	103	45.37
Ordinary	Sale	33	45.4
Ordinary	Sale	103	45.205
Ordinary	Sale	103	45.32
Ordinary	Sale	70	45.4
Ordinary	Sale	5	45.255
Ordinary	Sale	103	45.215
Ordinary	Sale	37	45.255
Ordinary	Sale	61	45.255
Ordinary	Sale	101	45.265
Ordinary	Sale	103	45.32
Ordinary	Sale	103	45.305
Ordinary	Sale	101	45.155
Ordinary	Sale	103	45.295
Ordinary	Sale	103	45.315
Ordinary	Sale	103	45.315
Ordinary	Sale	101	45.18
Ordinary	Sale	75	45.155
Ordinary	Sale	26	45.155
Ordinary	Sale	102	45.295
Ordinary	Sale	1	45.295
Ordinary	Sale	103	45.29
Ordinary	Sale	103	45.435
Ordinary	Sale	103	45.495
Ordinary	Sale	101	45.185
Ordinary	Sale	103	45.23
Ordinary	Sale	103	45.315
Ordinary	Sale	103	45.28
Ordinary	Sale	101	45.245
Ordinary	Sale	103	45.255
Ordinary	Sale	101	45.19
Ordinary	Sale	103	45.245
Ordinary	Sale	101	45.135
Ordinary	Sale	103	45.185
Ordinary	Sale	103	45.3
Ordinary	Sale	103	45.285
Ordinary	Sale	101	45.26
Ordinary	Sale	103	45.3
Ordinary	Sale	103	45.305
Ordinary	Sale	103	45.34
Ordinary	Sale	103	45.42
Ordinary	Sale	103	45.495
Ordinary	Sale	103	45.17
Ordinary	Sale	101	45.155
Ordinary	Sale	101	45.275
Ordinary	Sale	103	45.18
Ordinary	Sale	103	45.295
Ordinary	Sale	101	45.27
Ordinary	Sale	101	45.285
Ordinary	Sale	103	45.22
Ordinary	Sale	78	45.305
Ordinary	Sale	70	45.375
Ordinary	Sale	103	45.25
Ordinary	Sale	101	45.3
Ordinary	Sale	25	45.305
Ordinary	Sale	103	45.225
Ordinary	Sale	103	45.42
Ordinary	Sale	103	45.305
Ordinary	Sale	103	45.405
Ordinary	Sale	103	45.255
Ordinary	Sale	101	45.285
Ordinary	Sale	103	45.295
Ordinary	Sale	101	45.255
Ordinary	Sale	101	45.15
Ordinary	Sale	101	45.165
Ordinary	Sale	103	45.21
Ordinary	Sale	101	45.145
Ordinary	Sale	103	45.41
Ordinary	Sale	101	45.19
Ordinary	Sale	112	45.215
Ordinary	Sale	30	45.205
Ordinary	Sale	103	45.21
Ordinary	Sale	101	45.27
Ordinary	Sale	175	45.215
Ordinary	Sale	101	45.29
Ordinary	Sale	101	45.24
Ordinary	Sale	103	45.285
Ordinary	Sale	101	45.295
Ordinary	Sale	103	45.305
Ordinary	Sale	103	45.205
Ordinary	Sale	103	45.32
Ordinary	Sale	83	45.345
Ordinary	Sale	101	45.17
Ordinary	Sale	101	45.225
Ordinary	Sale	103	45.265
Ordinary	Sale	103	45.3
Ordinary	Sale	101	45.26
Ordinary	Sale	1	45.27
Ordinary	Sale	101	45.175
Ordinary	Sale	101	45.125
Ordinary	Sale	100	45.2
Ordinary	Sale	101	45.17
Ordinary	Sale	103	45.235
Ordinary	Sale	101	45.16
Ordinary	Sale	101	45.295
Ordinary	Sale	103	45.31
Ordinary	Sale	101	45.28
Ordinary	Sale	66	45.37
Ordinary	Sale	37	45.365
Ordinary	Sale	103	45.3
Ordinary	Sale	103	45.31
Ordinary	Sale	103	45.355
Ordinary	Sale	94	45.275
Ordinary	Sale	101	45.23
Ordinary	Sale	103	45.365
Ordinary	Sale	101	45.26
Ordinary	Sale	103	45.225
Ordinary	Sale	101	45.305
Ordinary	Sale	98	45.21
Ordinary	Sale	103	45.3
Ordinary	Sale	103	45.29
Ordinary	Sale	101	45.235
Ordinary	Sale	103	45.325
Ordinary	Sale	103	45.215
Ordinary	Sale	5	45.21
Ordinary	Sale	103	45.28
Ordinary	Sale	103	45.34
Ordinary	Sale	103	45.295
Ordinary	Sale	32	45.28
Ordinary	Sale	101	45.225
Ordinary	Sale	101	45.19
Ordinary	Sale	103	45.245
Ordinary	Sale	103	45.415
Ordinary	Sale	103	45.265
Ordinary	Sale	101	45.25
Ordinary	Sale	101	45.27
Ordinary	Sale	24	45.345
Ordinary	Sale	103	45.31
Ordinary	Sale	100	45.27
Ordinary	Sale	101	45.3
Ordinary	Sale	77	45.345
Ordinary	Sale	50	45.345
Ordinary	Sale	53	45.345
Ordinary	Sale	103	45.29
Ordinary	Sale	101	45.33
Ordinary	Sale	1	45.505
Ordinary	Sale	102	45.505
Ordinary	Sale	103	45.3
Ordinary	Sale	103	45.225
Ordinary	Sale	18	45.345
Ordinary	Sale	101	45.245
Ordinary	Sale	101	45.3
Ordinary	Sale	69	45.28
Ordinary	Sale	101	45.26
Ordinary	Sale	101	45.245
Ordinary	Sale	103	45.3
Ordinary	Sale	101	45.245
Ordinary	Sale	103	45.21
Ordinary	Sale	101	45.285
Ordinary	Sale	101	45.27
Ordinary	Sale	101	45.26
Ordinary	Sale	103	45.295
Ordinary	Sale	101	45.285
Ordinary	Sale	101	45.3
Ordinary	Sale	101	45.285
Ordinary	Sale	101	45.3
Ordinary	Sale	101	45.285
Ordinary	Sale	101	45.19
Ordinary	Sale	103	45.49
Ordinary	Sale	101	45.265
Ordinary	Sale	101	45.235
Ordinary	Sale	103	45.21
Ordinary	Sale	103	45.295
Ordinary	Sale	103	45.415
Ordinary	Sale	101	45.27
Ordinary	Sale	103	45.275
Ordinary	Sale	103	45.305
Ordinary	Sale	103	45.3
Ordinary	Sale	103	45.34
Ordinary	Sale	101	45.25
Ordinary	Sale	101	45.155
Ordinary	Sale	73	45.205
Ordinary	Sale	103	45.29
Ordinary	Sale	19	45.495
Ordinary	Sale	84	45.495
Ordinary	Sale	103	45.22
Ordinary	Sale	84	45.305
Ordinary	Sale	103	45.305
Ordinary	Sale	106	45.26
Ordinary	Sale	18	45.21
Ordinary	Sale	101	45.27
Ordinary	Sale	103	45.29
Ordinary	Sale	103	45.38
Ordinary	Sale	103	45.455
Ordinary	Sale	103	45.27
Ordinary	Sale	103	45.3
Ordinary	Sale	103	45.26
Ordinary	Sale	103	45.245
Ordinary	Sale	103	45.275
Ordinary	Sale	101	45.265
Ordinary	Sale	103	45.245
Ordinary	Sale	17	45.3
Ordinary	Sale	103	45.295
Ordinary	Sale	20	45.28
Ordinary	Sale	83	45.28
Ordinary	Sale	101	45.27
Ordinary	Sale	101	45.295
Ordinary	Sale	101	45.125
Ordinary	Sale	107	45.275
Ordinary	Sale	349	45.3
Ordinary	Sale	194	45.405
Ordinary	Sale	133	45.265
Ordinary	Sale	119	45.27
Ordinary	Sale	88	45.29
Ordinary	Sale	150	45.29
Ordinary	Sale	20	45.28
Ordinary	Sale	100	45.275
Ordinary	Sale	103	45.225
Ordinary	Sale	62	45.215
Ordinary	Sale	30	45.285
Ordinary	Sale	27	45.28
Ordinary	Sale	34	45.28
Ordinary	Sale	70	45.22
Ordinary	Sale	5	45.27
Ordinary	Sale	150	45.305
Ordinary	Sale	68	45.3
Ordinary	Sale	400	44.91
Ordinary	Sale	2,123	44.91
Ordinary	Sale	229	44.91
Ordinary	Sale	5,305	44.91
Ordinary	Sale	1,732	44.91
Ordinary	Sale	693	44.91
Ordinary	Sale	1,732	44.91
Ordinary	Sale	346	45.605
Ordinary	Sale	308	45.555
Ordinary	Sale	150	45.565
Ordinary	Sale	161	45.425
Ordinary	Sale	231	45.425
Ordinary	Sale	150	45.585
Ordinary	Sale	222	45.43
Ordinary	Sale	196	45.41
Ordinary	Sale	150	45.22
Ordinary	Sale	189	45.57
Ordinary	Sale	63	45.42
Ordinary	Sale	121	45.42
Ordinary	Sale	29	45.275
Ordinary	Sale	28,692	45.375
Ordinary	Sale	65	45.27
Ordinary	Sale	116	45.1775
Ordinary	Sale	101	45.3975
Ordinary	Sale	71	45.3
Ordinary	Sale	79	45.3
Ordinary	Sale	69	45.37
Ordinary	Sale	66	45.285
Ordinary	Sale	35	45.555
Ordinary	Sale	45	45.565
Ordinary	Sale	45	45.585
Ordinary	Sale	211	45.64
Ordinary	Sale	304	45.665
Ordinary	Sale	44	45.31
Ordinary	Sale	112	45.31
Ordinary	Sale	200	45.49
Ordinary	Sale	200	45.5
Ordinary	Sale	181	45.43
Ordinary	Sale	162	45.5
Ordinary	Sale	98	45.62
Ordinary	Sale	185	45.665
Ordinary	Sale	91	45.515
Ordinary	Sale	5	45.275
Ordinary	Sale	10	45.405
Ordinary	Sale	4	45.275
Ordinary	Sale	4	45.51
Ordinary	Sale	101	45.31
Ordinary	Sale	108	45.145
Ordinary	Sale	10,000	45.674518
Ordinary	Sale	35,757	45.85449539
Ordinary	Sale	120,000	45.80942438
Ordinary	Sale	13	45.605
Ordinary	Sale	8	45.57
Ordinary	Sale	9	45.575
Ordinary	Sale	66	45.575
Ordinary	Sale	7	45.575
Ordinary	Sale	91	45.495
Ordinary	Sale	91	45.215
Ordinary	Sale	2	45.25
Ordinary	Sale	91	45.225
Ordinary	Sale	91	45.26
Ordinary	Sale	91	45.235
Ordinary	Sale	91	45.195
Ordinary	Sale	91	45.31
Ordinary	Sale	181	44.91
Class of relevant security	Purchase/sale	Number of securities	Price per unit USD
ADR	Sale	600	171.545
ADR	Sale	393	171.062137
ADR	Sale	120	171.117
ADR	Sale	120	170.971
ADR	Sale	99	171.96
ADR	Sale	21	171.98
ADR	Sale	13,887	171.443208
ADR	Sale	162	171.21
ADR	Sale	30	171.21
ADR	Sale	7,212	171.166527
	Total Purchases	1,573,148
	Total Sales	300,717

(b) Cash-settled derivative transactions

Class of relevant security	Product description e.g. CFD	Nature of dealing e.g. opening/closing a long/short position, increasing/reducing a long/short position	Number of reference securities	Price per unit GBP
Ordinary	CFD	Increasing a short position	200,000	46.02219248
Ordinary	CFD	Increasing a short position	10,000	45.675432
Ordinary	CFD	Increasing a short position	100,000	45.49415704
Ordinary	CFD	Increasing a short position	100,000	45.49415704
Ordinary	CFD	Increasing a short position	400,000	45.84329747
Ordinary	CFD	Reducing a short position	10,000	45.674518
Ordinary	CFD	Reducing a short position	35,757	45.85449539
Ordinary	CFD	Reducing a short position	120,000	45.80942438

(i) Writing, selling, purchasing or varying

Class of relevant security

Product description e.g. call option

Writing, purchasing, selling, varying etc.

Number of securities to which option relates

Exercise price per unit

Type

e.g. American, European etc.

Expiry date

Option money paid/ received per unit USD

ADR

Listed call-option

Selling

25,000

175

American

18/01/2019

3.70

(ii) Exercise

Class of relevant security

Product description

e.g. call option

Exercising/ exercised against

Number of securities

Exercise price per unit GBP

(d) Other dealings (including subscribing for new securities)

Class of relevant security

Nature of dealing

e.g. subscription, conversion

Details

Price per unit (if applicable) GBP

4. OTHER INFORMATION

(a) Indemnity and other dealing arrangements

Details of any indemnity or option arrangement, or any agreement or understanding, formal or informal, relating to relevant securities which may be an inducement to deal or refrain from dealing entered into by the person making the disclosure and any party to the offer or any person acting in concert with a party to the offer:

Irrevocable commitments and letters of intent should not be included. If there are no such agreements, arrangements or understandings, state "none"

(b) Agreements, arrangements or understandings relating to options or derivatives

Details of any agreement, arrangement or understanding, formal or informal, between the person making the disclosure and any other person relating to:

(i) the voting rights of any relevant securities under any option; or

(ii) the voting rights or future acquisition or disposal of any relevant securities to which any derivative is referenced:

If there are no such agreements, arrangements or understandings, state "none"

Is a Supplemental Form 8 (Open Positions) attached?

Yes

Date of disclosure:	21/12/2018
Contact name:	Olivier Vero
Telephone number:	+44 20 7676 6969

Public disclosures under Rule 8 of the Code must be made to a Regulatory Information Service.

The Panel's Market Surveillance Unit is available for consultation in relation to the Code's disclosure requirements on +44 (0)20 7638 0129.The Code can be viewed on the Panel's website at www.thetakeoverpanel.org.uk

SUPPLEMENTAL FORM 8 (OPEN POSITIONS)

DETAILS OF OPEN STOCK-SETTLED DERIVATIVE (INCLUDING OPTION) POSITIONS, AGREEMENTS TO PURCHASE OR SELL ETC.

Note 5(i) on Rule 8 of the Takeover Code (the "Code")

1. KEY INFORMATION

Full name of person making disclosure:	SOCIETE GENERALE SA
Name of offeror/offeree in relation to whose relevant securities the disclosure relates:	Shire Plc

2. STOCK-SETTLED DERIVATIVES (INCLUDING OPTIONS)

Class of relevant security	Product description e.g. call option	Written or purchased	Number of securities to which option or derivative relates	Exercise price per unit GBP	Type	Expiry date
Class of relevant security	Product description e.g. call option	Written or purchased	Number of securities to which option or derivative relates		e.g. American, European etc.	Expiry date
Ordinary	Listed call-option	Sale	150,000	32	American options	21/12/2018
Ordinary	Listed put-option	Sale	150,000	32	American options	21/12/2018
Class of relevant security	Product description e.g. call option	Written or purchased	Number of securities to which option or derivative relates	Exercise price per unit USD	Type	Expiry date
ADR	Listed call-option	Purchase	75,000	170	American option	18/01/19
ADR	Listed call-option	Sale	75,000	165	American option	18/01/19
ADR	Listed call-option	Purchase	55,600	180	American option	18/01/19
ADR	Listed call-option	Purchase	3,800	175	American option	21/12/2018
ADR	Listed call-option	Sale	104,400	175	American option	18/01/2019
ADR	Listed call-option	Purchase	41,800	200	American options	18/01/2019
ADR	Listed call-option	Sale	15,000	185	American options	18/01/2019
ADR	Listed call-option	Purchase	33,900	190	American options	18/01/2019
ADR	Listed put-option	Purchase	20,000	170	American options	18/01/2019
ADR	Listed put-option	Sale	20,000	140	American options	18/01/2019
ADR	Listed put-option	Sale	20,000	155	American options	18/01/2019

3. AGREEMENTS TO PURCHASE OR SELL ETC.

Full details should be given so that the nature of the interest or position can be fully understood:

It is not necessary to provide details on a Supplemental Form (Open Positions) with regard to cash-settled derivatives.

The currency of all prices and other monetary amounts should be stated.

The Panel's Market Surveillance Unit is available for consultation in relation to the Code's disclosure requirements on +44 (0)20 7638 0129.

The Code can be viewed on the Panel's website at www.thetakeoverpanel.org.uk.

This information is provided by RNS, the news service of the London Stock Exchange. RNS is approved by the Financial Conduct Authority to act as a Primary Information Provider in the United Kingdom. Terms and conditions relating to the use and distribution of this information may apply. For further information, please contact rns@lseg.com or visit www.rns.com.

END

RETEAEAFADNPFFF

Date		Source	Headline
8th Jan 2019	5:30 pm	GNW	Director/PDMR Shareholding
8th Jan 2019	3:20 pm	RNS	Form 8.3 - Shire plc
8th Jan 2019	3:19 pm	RNS	Form 8.3 - Takeda Pharmaceutical Company Limited
8th Jan 2019	3:13 pm	RNS	Form 8.3 - Shire plc
8th Jan 2019	3:07 pm	RNS	Form 8.5 (EPT/NON-RI)
8th Jan 2019	2:28 pm	RNS	Form 8.5 (EPT/RI) - Replacement of Shire
8th Jan 2019	2:23 pm	RNS	Form 8.5 (EPT/RI) - Replacement of Shire
8th Jan 2019	2:21 pm	RNS	Form 8.5 (EPT/RI) - Replacement of Shire
8th Jan 2019	1:57 pm	RNS	Form 8.3 - Takeda Pharmaceutical Company Limited
8th Jan 2019	1:27 pm	RNS	Form 8.3 - Shire plc
8th Jan 2019	12:31 pm	RNS	Form 8.3 - Takeda Pharmaceutical Company Limited
8th Jan 2019	12:29 pm	RNS	Form 8.3 - Takeda Pharmaceutical
8th Jan 2019	12:27 pm	RNS	Form 8.3 - Shire plc
8th Jan 2019	11:42 am	RNS	Form 8.5 (EPT/NON-RI)
8th Jan 2019	11:33 am	RNS	Form 8.5 (EPT/NON-RI)- Shire Plc
8th Jan 2019	10:49 am	RNS	Form 8.5 (EPT/RI)
8th Jan 2019	10:41 am	RNS	Form 8.3 - Takeda Pharmaceutical Company Limited
8th Jan 2019	10:26 am	RNS	Form 8.5 (EPT/RI)- Shire plc
8th Jan 2019	9:51 am	RNS	Form 8.3 - Shire Plc
8th Jan 2019	8:44 am	RNS	Form 8.5 (EPT/RI) - SHIRE PLC
8th Jan 2019	7:00 am	RNS	Form 8.3 - Takeda Pharmaceutical Company Limited
8th Jan 2019	7:00 am	GNW	Scheme becomes effective
7th Jan 2019	5:00 pm	GNW	Holding(s) in Company
7th Jan 2019	3:42 pm	RNS	Form 8.5 (EPT/RI) - Amendment
7th Jan 2019	3:20 pm	RNS	Form 8.3 - Shire plc
7th Jan 2019	3:02 pm	RNS	Form 8.3 - Shire plc
7th Jan 2019	3:00 pm	RNS	Form 8.5 (EPT/NON-RI)
7th Jan 2019	3:00 pm	RNS	Form 8.3 - Shire plc
7th Jan 2019	2:59 pm	RNS	Form 8.3 - Takeda Pharmaceutical
7th Jan 2019	2:50 pm	PRN	Form 8.3 - Shire Plc
7th Jan 2019	2:49 pm	RNS	Form 8.3 - Shire plc
7th Jan 2019	2:47 pm	RNS	Form 8.3 - Takeda Pharmaceutical Company Limited
7th Jan 2019	2:45 pm	BUS	Form 8.3 - Shire plc
7th Jan 2019	1:55 pm	RNS	Form 8.3 - Takeda Pharmaceutical Company Limited
7th Jan 2019	1:54 pm	RNS	Form 8.3 - Shire plc
7th Jan 2019	1:39 pm	RNS	Form 8.3 - [Shire Plc]
7th Jan 2019	1:32 pm	RNS	Form 8.5 (EPT/RI) - Replacement of Shire
7th Jan 2019	1:29 pm	RNS	Form 8.5 (EPT/RI) - Replacement of Shire
7th Jan 2019	12:57 pm	RNS	Form 8.3 - Takeda Pharmaceutical Company Limited
7th Jan 2019	12:56 pm	RNS	Form 8.3 - Shire plc
7th Jan 2019	12:42 pm	RNS	Form 8.5 (EPT/NON-RI)
7th Jan 2019	11:52 am	RNS	Form 8.3 - Takeda Pharmaceutical Company Limited
7th Jan 2019	11:43 am	BUS	Form 8.3 - SHIRE PLC
7th Jan 2019	11:30 am	RNS	Form 8.3 - Takeda Pharmaceutical Company Limited
7th Jan 2019	11:27 am	RNS	Form 8.3 - Shire plc
7th Jan 2019	11:01 am	RNS	Form 8.5 (EPT/RI)- Shire plc
7th Jan 2019	10:59 am	RNS	Form 8.5 (EPT/NON-RI)- Shire Plc
7th Jan 2019	10:35 am	RNS	Form 8.5 - Shire plc
7th Jan 2019	10:16 am	RNS	Form 8.5 (EPT/RI) - SHIRE PLC
7th Jan 2019	10:13 am	RNS	Form 8.5 (EPT/RI) - Amendment

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