Proteome Regulatory News (PRM)

Proteome Sciences plc

("Proteome Sciences" or the "Company")

Director Dealing

1st October, 2014 - The Board of Proteome announces that Geoff Ellis, Finance Director, has today been granted options over 300,000 ordinary shares of 1p each under the Company's 2011 Long Term Incentive Plan ("LTIP"). These options are exercisable at a price of 1p per ordinary share and are subject to a minimum three year vesting period and the achievement of certain performance criteria under the LTIP rules.

These options represent approximately 0.14% of the Company's current issued share capital. Mr. Ellis currently holds no other options or shares in the Company.

- Ends -

For further information please contact:

Proteome Sciences plc

Christopher Pearce, Executive Chairman

Dr. Ian Pike, Chief Operating Officer Tel: +44 (0)1932 865065

Geoff Ellis, Finance Director

Cenkos - Nominated Adviser

Stephen Keys/Mark Connelly /Callum Davidson Tel: +44 (0)20 7397 8900

finnCap - Joint Broker

Geoff Nash (Corporate Finance) Tel: +44 (0)20 7220 0500

Tony Quirke (Broking)

IKON Associates - Public Relations

Adrian Shaw Tel: +44 (0)1483 271291